Inactive Ingredients Of Qualitest Or Leading Pharma Lorazepam (Page 5) (Top voted first)

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What are the inactive ingredients of Qualitest lorazepam or Leading Pharma lorazepam? Does anybody know?

It seems that its formula might have been changed because I feel 1mg is less effect than before or does not work. I used to take Ativan 1mg before abroad and one month from Kaiser in the U.S. but they gave me refill as generic lorazepam (Qualitest). I felt 50-60% effectiveness compared to Ativan(brand lorazepam). I can't take Watson lorazepam as it does not work for me causing side effects (rapid heart beats, sweating, anxiety, dehydration). Qualitest has less side effect (less dehydrated than Ativan) I did not have physical dependence on Ativan for long time and quit too. But this generic lorazepam is getting less effective over a few months.

Also my pharmacy had changed Qualitest to Leading Pharma without notice so I had to get new transcript for new pharmacy for qualitest (I transferred once).

I did not take it for mental problem (anxiety or panic attach) but for side effect of levothyroxine (I should take it as I got my thyroid gland removed). Ativan has calming effect and reduces heart beats, sweating, and stiffness and helps sleeping a little as I suffer from some pains. It does not fix my problem but reduces temporarily. Zanax does not work. Cymbalta does not work. All depression medicine does not work. With Cymbalta, I became unconscious and was hospitalized. I almost died taking Prozac due to side effects and worsened my symptoms. Ativan only helps a little.

I called most pharmacies in LA but many of them sell Leading Pharma lorazepam and some sell Watson. Most pharmacies do not receive return once it is opened (only one pill is taken) while Rite Aid does and during the period of medication, patients can't buy another lorazepam even with new prescription so if the medicine cause side effects or does not work, customer have to wait until refill period comes.

I found only one pharmacy selling Qualitest lorazepam but most others sell Leading Pharma, I don't know why but maybe because of their marketing. So I may change to Leading Pharma but am worried that it does not work like Watson.

I wonder if anybody tried Leading lorazepam and if it works, though effects are different according to each individual. Ativan in the U.S. is very expensive ($2600 for 1mg 30 tablet) and most doctors do not prescribe it and insurance is mostly not covered or do not want to pay for it. That's why Kaiser gave me brand Ativan only once and changed it to generic.

114 Replies (6 Pages)

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73

Re: Judi (# 64) Expand Referenced Message

Judi I was in your shoes many times thinking maybe I should just come off from this stuff. I won't give you the long version but I went.against my pdoc and internal medicine doctor and checked myself into detox. One of the worst life events I've ever been through. The sad thing is that I failed to be able to cope with extreme panic disorder without being on something. My doc met me at the front desk and said here's a script for Ativan you'll need to be on this most likely for life. Only good thing that came of that we found a benzo that actually worked and I was able to live a somewhat normal life. There's a English lady that has devoted her life to the study of benzodiazepines. She feels that there's nothing wrong with being on them. And to rush trying to come off from them is not the right approach. I'll try and find her name and posted it later. If you aren't being forced to come down my advice would be take your time. :)

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75

Richard (# 70) --

Yup that's the lady. Showed some of her YouTube videos to one of my docs years ago ---She was anti benzo freak. Thought all the new SSRI's & SNRI's were the next best thing to Murphy's Oil. Ended up with a permanent ring finger twitch from Effexor. I'd already been through the old skool antidepressants that made a basket case out if me back in the early 80's. You have no idea how important it is to keep your medical jacket. (Well at least some don't)

As for Valium you couldn't get me to take that stuff even if it was free. The half life and a short time effects of its usage is worst then Ativan. I only took Valium when I was on a dusty island with a 40 mile perimeter, water on one side and mountains on the other. Ativan was just making the scene about that time. Was loaded up on Tofranil and Amitriptyline. The 3 bar shoulder board thought that was a great combination for panic disorders. That gave me a racing heart of 134 and hallucinations. ;) Oh yeah he put me back out on the line turning multi-million dollar equipment.

But back to Valium I only took it as needed thankfully. Yes I realize that Valium was the happening drug at one time. Actually Miltown was a lot more popular in the timeframe you spoke of. My aunt was on that junk. Turned her into something horrible.

Yes the folks that make these pills we're on knew just how addictive they were before they hit the open market. But the question is what else would they have given folks that were debilitated from panic disorder. I suppose there might be a magic bullet we don't know about that works? Dunno...

Lorazepam works just great as long as they stop changing the formulas. Then they do what they should do for many. As we've all said out here one might not work for one while another may work for someone else. So far I've only had two work efficiently.

As for many we are shunned for being on what were on only because the new drugs are the real McCoy according to many pdoc's. The sad thing is that isn't all true for everyone. You see if those drugs worked trust me when I say this I'd be on them. All my trials and errors were performed under close monitoring. Ok enough of the past. I'm in hopes this Sandoz will balance out for me long enough to start back to my beginning. But as of now it's got me a bit unhinged. This too shall pass.

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78

Re: Richard (# 77) Expand Referenced Message

Please contact the FDA: https:/­/­www.fda.gov/­ForConsumers/­ConsumerUpdates/­ucm095859.htm

I did over my meds not working. Same manufacturers. People need to get the word out!

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79

Penso que os benzodiazepínicos,incluindo o Lorazepam,são realmente bastante eficazes,no tratamento da ansiedade,mas não há como negar o seu grande potencial de dependência psicológica,ao menos psicológica.O problema desta classe de medicamento 'benzos',que também promovem um relaxamento neuromuscular,que facilitam a indução do sono,mesmo os que não pertencem à classe dos indutores do sono,que são de curtíssima duração,é ,a meu ver,que após alguns anos de uso contínuo,mesmo em baixas dosagens,podem,além de desenvolver a tolerância 'aumento da dose',para o mesmo efeito,acontece com certa frequência,a necessidade de se adequar as dosagens;nem sempre para um aumento de dosagem,mas também aos horários;quanto menor a dosagem eficaz,melhor;se tomamos 1 mg de alprazolam ou lorazepam,por exemplo,e sentimos o alívio dos sintomas,melhor é procurar manter ao máximo,com esta dosagem;uma simples miligrama a mais,podem nos deixar muito desatentos,letárgicos,e 'sem emoções',principalmente à longo prazo,o que não é nada saudável;as vezes é preciso combinar com algum antidepressivo,que possua efeitos ansiolíticos,como a sertralina,fluoxetina,dentre outros,assim como em certas situações,inserir o uso de algum psicoestimulante leve,como a ritalina,modafinila,pemolina magnésica,dentre outros não deve serem completamente descartados ou desconsiderados;ao menos podem eventualmente diminuírem as sequelas cognitivas reversíveis,assim como serem úteis,no 'desmame' diminuição gradativa do fármaco benzodiazepínico..

Google Translate (may not be 100% accurate):

I think benzodiazepines, including Lorazepam, are actually quite effective in treating anxiety, but there is no denying their great potential for psychological, at least psychological, dependence. The problem with this class of 'benzos' drug, which also neuromuscular relaxation, which facilitate the induction of sleep, even those that do not belong to the class of sleep inducers, which are of very short duration, is, in my view, that after some years of continuous use, even at low dosages, they can, in addition, to increase dose tolerance, for the same effect, the need to adjust the dosages, not always for an increase in dosage, but also for the times, the lower the effective dosage, the better; we take 1 mg of alprazolam or lorazepam, for example, and we feel the relief of the symptoms, it is better to try to keep to the maximum, with this dosage, a simple milligram more, can make us very inattentive, lethargic, and without emotion s, mainly in the long term, which is not at all healthy, sometimes it is necessary to combine with some antidepressant, which has anxiolytic effects, such as sertraline, fluoxetine, among others, as well as in certain situations, insert the use of some psychostimulant such as ritalin, modafinil, magnesium pemoline, among others should not be completely discarded or disregarded, at least may eventually reduce the reversible cognitive sequelae, as well as being useful in 'weaning' gradual decrease of the benzodiazepine drug ..

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80

Re: Richard (# 14) Expand Referenced Message

Yes the leading brand lorazepam 2mg works it's sad seeing all these reviews where people believe this pill is garbage this company was awarded 40 million dollars to continue manufacturing they are definitely in it for quality and business and this pill does not taste like sugar it tastes sweet but all other brands of generic lorazepam have tasted sweeter it of course your body knows what is needed to feel well and with generic pills they are made differently and people either got the feeling of relief or aren't satisfied and go elsewhere but the saddest thing here is all these bad reviews I believe people are just agreeing to get their liking and their making of the generic pill there bodies are used to and that's not right

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82

Re: Hnnypooh (# 81) Expand Referenced Message

I totally agree I mean ive been on lorazepam 26 years and yes I'll be the first to agree some makers are better than others but these lorazepam made by LEADING PHARMA are not the best but they do work is what I'm getting at here

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83

Re: Charlii77 (# 82) Expand Referenced Message

When I first joined this discussion I disagreed with everything negative said against Leading and Actavis....well..after being on them for a year.....I have no problems admitting I was wrong...several months ago I started having tachycardia during the day with any slight exertions..up to 171 bpm...and at night waking me up 3-4 times a night with lower high heart rates until recently they went over 150.....not good. Literally just came back from docs .....I barely got the words Actavis’ “Watson” is not like the old Watson...it’s not as effective and neither is Leading..out of my mouth ...when he interrupted me to say he has heard this from many many patients in the last 3 months.....so he wrote me a script of a light dose of a benzo w/ a longer half life to take at night...along with the Actavis Lorazepam. .05 mg of Klonopin. It’s a shame American manufacturers have sold out their patients so they can make higher profits.... ALL Lorazepam is now made in India ... Thus they do not, by law, have to adhere to the "no less than 5% variation" in the active ingredient FDA law... As an import they can vary 5-20%.

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84

Re: Richard (# 83) Expand Referenced Message

I have svt and I'm also on heart medication and the 2mg lorazepam from LEADING PHARMA been on them for over a month no problems I personally think Watson brand is the best also keep in mind I've noticed these comments are from last year has any one gotten an up date who knows maybe they are being made better as of now I hear so much about how these pills taste like sugar they do not taste like sugar they taste exactly like the inactive ingredient prcillin potassium

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86

Re: Charlii77 (# 80) Expand Referenced Message

I think that every pill should work the same. We should not be put through tests. They should all be required to use the same amount of active ingredients. It’s not fair that people such as myself should have to be sick and going through withdrawal symptoms because we are treated like guinea pigs. If you needed a heart pill and one didn’t work properly would you continue to take it?? People can have seizures etc not having the proper dose. I was able to be put on the brand name Ativan and have my insurance cover it. Thank God! Guess what? I actually take less than I did on generics.

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89

Yes I'm on leading lorazepam it taste like sugar because of the potassium it has an inactive ingredient these comments and side effects of this brand of pill causing all these death side effects are just ridiculous give them a try all the generic lorazepam are the same to me good luck

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90

Re: Hnnypooh (# 88) Expand Referenced Message

How long were you taking the LEADING PHARMA LORAZEPAM and what were your symptoms

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92

Re: David (# 2) Expand Referenced Message

Yes the potassium in the leading brand lorazepam is a tablet disintegrate meaning you will get the most out of the pill if taken sublingually instead of oral I put one under my tongue in about 20 seconds it's dissolved and I don't swallow for about 3 minutes and I feel immediate relief I'm starting to wonder if this tablet is only supposed to be used sublingually hope this helps

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93

Re: Hnnypooh (# 91) Expand Referenced Message

I went through the same. Ended up in ER with severe panic attack with very high heart rate..

Go back to thread maybe 6 months ago. Leading Pharma does not work for me..their pills are a little large for sublingual???

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94

Leading works great. It’s not like Mylan but better than the other placebos. Yet to try Teva. Would like to hear if someone can compare the two

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95

Re: Dee (# 1) Expand Referenced Message

Clonazepam should have a sweet taste ! The more - the more active ingredients

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96

Re: Abomb (# 94) Expand Referenced Message

I think it all depends on the individual.....and what we believe is working for us...if Leading works for you, then stick with it.......when my old (the original-non-India) Watson was first changed to Leading I found it to be just fine..but after a few months my anxiety levels had risen....and others here also noted Leading to be rather ineffective.....my pharmacy then switched to Teva (still says "Watson" but its Actavis using the old molds)....then Leading was actually more desirable...and no longer available to my pharmacy (probably Actavis was cheaper)...yet...life goes on..... I tried an experiment...if you've lost faith in your generic (I've been on benzos for over 50 years (lorazepam 35+-same dose as I began with (2mg 3x day).......try skipping a dose....lorazepam washes out rather fast compared to valium/klonopin.....by the time you haven't taken your next dose..evaluate how you feel.....try skipping the next (that's as far as I got)......now take your "weak" generic......suddenly in 1/2 hour it seems so much more powerful than I thought it was.....(I got this idea from years ago when I tried fasting..... I always had utterly hated chestnuts........but into day three of the fast I gave in..grabbed the first thing I could find (I was out shopping)...a bag of pre-peeled roasted chestnuts... I've been loving them ever since.

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97

Re: Judy (# 6) Expand Referenced Message

Agree. A disgrace and a rip off.

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98

Re: Charlii77 (# 80) Expand Referenced Message

Nothing works like the Mylan brand which was discontinued because...ohh because it works the best! Great reason. Leading is now the best. The others are trash. I never tried teva brand though.

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99

Leading makes junk. Is the FDA aware?

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100

I was on Lorazepam by Watson for a while, no problems, got a refill 1-9-2020 , new manufacturer,leadingPharma , kinda afraid to take it. seems to have a cinnimon like taste when hitting the mouth. Do not know what to do next. called CVS Pharmacy. Change manufacturer without notice of which I'm getting sick and tired of.

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