Hysingla Experience (Page 2) (Top voted first)

This is day 3 of me taking Hysingla 20mg after taking Norco 10/325mg three to four times a day. So far I've noticed some wacky side effects. The pill seems to kick in at around 8hrs, and I can't keep my eyes open, I get a rush of anxiety and nausea. I've taken EVERY other ER opiate in the world and none of them did this to me. I do notice that it has lessened my extreme pain already and I have taken a few norcos on top of it thru out the day, but the 8hr mark seems to be like a different world kicking in. Has anyone been on this for awhile, went thru these side effects and then came out the other end actually liking this med? I can find NOTHING on the internet regarding much experience or reviews out there on people who are taking this med. I've woken up in the middle of the night with abdominal pains, anxiety and an overall feeling of weird. Then it passes and I fall back to sleep, and I just feel so hungover. Also it's like every three hours or so it will ''kick in'' again with the can't keep my eye open thing, the nausea, etc. I started out the first two days not eating much (took away my will to eat) so today I made sure I ate a large meal before the 8 hr mark kicked in, but still feel so freaking weird! Please, can anyone out there give me some feedback?

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Was on hysingla ER for 6 months.. Would only cover my pain moderately from hour 8 to hour 15 when blood levels were highest and provided almost no relief for the remainder of the 24 hours. Went back to norco IR and notice that ny tolerance is much higher! Before he started me on hysingla I could take a norco 7.5 and I would cover my pain for 4 hours ... Now it takes 1 1/2 to cover with added ibuprofen ...

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Hi all, I was on oxycotin twice a day, with Percocet 10 mg for breakthrough pain. I was on this combination for a few years. After receiving a letter from my insurance company stating they are no longer covering oxycontin for anyone anymore, and they recommend Hysingla. I took the letter to my Dr. He had not heard of it, my pharmacy had not heard of it, etc. That was a little scary to me that no one has heard of it. The last time I saw my Dr he prescribed Hysingla 60 mg, with Norco for breakthrough pain. This is by far the best drug that has ever worked for me. It lasts the full 24 hours for me. I take it in the morning with my coffee. It doesn't make me feel tired at all, in fact the oxycontin did make me feel tired. I am able to do more now, go places with hubby, I feel like I have a good quality of life back. I have no side effects from it at all. Getting that letter was the best thing that could have happened to me, because I never would have heard of Hysingla if I hadn't. My Dr. did some research, if you're on a high dose of your previous medication then you'll need a higher dose of Hysingla. To find out just call your insurance. I was on 30 mg of oxycontin before, so 60 mg of Hysingla is workable. I may ask to go up to 80 mg. I've been on the Hysingla for 2 weeks now, I'm willing to give it a chance. I find if I take it in the morning, then a Norco when I go to bed it carries me through the night. The other bonus is I have slept better in the last 2 weeks than ever before. For those of you getting on it give it a shot, it works for me, and I have a friend who was recently put on it, he has no complaints either. It works better then any medication out there that's long term.

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I have been on narco 10/325 for about 15 years now in combination with whatever was out there to help reduce my pain. I am now 72 with osteoporosis, degenerative joint disease, complications from an auto accident, and more. Fentanal patches almost killed me. Over the past five years I was on OxyContin, with hydrocodone which worked well but began to slowly fade out. My Pain Specialist changed me to hysingla about six months ago and it is now working great for me. It took a little time to adjust my medications so they would work best for me. I now take hydro 10/325 3X a day at 8am, 2pm, and 10pm and hysingla ER 30mg two times a day at 8am,and 10pm which seems to balance effectiveness of each. My pain level holds around 6 to 7 with spikes as high as 9 at times but not that often. I can take another hydro if needed to reduce the pain but try not to. My life is better now with a tolerable pain level. I very seldom go to a 6 even with bed rest and know this is for the rest of my life. I hope this might help someone with similar problems.

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Re: Christine (# 3)

SAME, I have never been SO miserable in my life. I felt like I was in withdraw too. I had been taking methadone for long lasting pain w/ 10 mg. Hydrocodone 3 times a day. Mind you I have severe pain having Spondolothesis, stenosis, scoliosis, arthritis and a fracture in my back. My legs and back ached SO bad all month long on this. I have been off the methadone for 3 mos so no withdraw from that anymore. I felt severely depressed and anxious, almost like I felt doomed in a way, dreadful. Like I was absolutely miserable on this crap. It seems like it takes around 10 to 14 hours to kick in and the only way I can tell, as the pain doesn't ease up, it's that I start feeling weird. My head feels full like I'm on speed or something, can't sleep well, have a rash on upper arms and my urine barely comes out. I read somewhere that these kind of meds are full of glue. I decided I'd dissolve one in some water, to see how long it took to dissolve. Never dissolved, it swelled to the size of a huge nickel and to about 3/4" thick! I took a fork to see what the consistency was and OMG, it was the stickiest, stringiest crap ever- like glue, went back and checked it after it dried and it was like that tacky glue they use in retail packaging or to hang pictures, it wadded up just like that stuff and the ball was about 2" around in size!!! Unbelievable this crap is on the market. WAY overpriced too. DO NOT waste your time and money trying this for severe pain. Absolutely did not touch my pain and made me feel depressed, doomed, and anxious. It was the 10 mg. I'd rather suffer in pain than feel like this again, can't wait til it's completely out of my system. Still feel weird and haven't taken one in 36 hours.

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is 20miligrams of hysingla the same as4 7.5 hydrocodones.and will it help with chronic pain?

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yes I was on vicoprofin off and for about 4 years, the problem is I got very addicted to it and was taking more to relieve the pain. I feel it does work better than vicodin and or Hysingla. I currently take hysingla er 40 mg. 1x day with 4 vicodin as breakthrough medication. Seems like a lot but the vicodin is a very low dose. I did feel that the vicoprofin worked better on emergent pain. Hope this helps.

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First time on Hysingla ER and it is the worst med I have ever taken. I only stayed on for three days, but that was enough...hot flashes, nausea, drowsiness, out of it in general. After only three days, I experienced withdrawal symptoms when I stopped the medication. Terrible drug.

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I just started on 30mg. How long should I wait until it starts working?

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Hi donna. I hope your finding relief. When you went back to doctor, what did they do? I'm still experiencing the headaches, cramping and just really tired all the time? Do the side effects get any better? Thank you

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Took hysingla for 3 MO.
Quit working after about 8hr. Took 5mg hydrocodone to get by. Now wants me to take lyrica and opana.. Really scares me cause I have bad reaction to morphine.. Also added claritin D.. Any ideas to help?

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I'AM ON 30MG OF HYSINGULAR AND I FEEL LIKE MY LEGS ARE VERY HEAVY DO ANY OF YOU HAVE THAT SIDE EFFECT?

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So sorry Susie. I had a terrible time with that med. Tired, nausea, not eating. My body felt like cement. They did not help. It was absolutely the worst med I have ever taken.

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I have been on hysingla 30mg for about 6months. It has helped me to start taking it at around 10pm, that way when I get up in the morning I feel pretty good so I can go to work. my doctor will not give me any breakthrough pain medicine which would help some. I have to say this medicine has really worked well for me.Hang in there maybe it will do the same for you. Remember take before bed time

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I have been on hysingla w Norco 10's twice a day for break thru pain. I haven't had any extreme side effects or pain relief either. It is a time release hydrocodone, which is the same ingredient as in Norco. Hysingla has no added tylenol. Lortab was hydrocodone w 500mg of tylenol, Norco is lortab only w less tylenol, 325mg. Hysingla works vert subtly on me. I have to supplement it w ibuprofen. The break through medicine isn't enough either. I exercise, and ice my back. I practice meditation. I know Alabama is suffering from an opioid epidemic as dr. Are prescribing the highest per pt. In the country. I feel I can't ask for an increase in hysingla 30 mg. As in your situation I might get ALL my medicine discontinued. I hope u can find a better long acting med for ur pain.

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Hi. My name is Cynthia. I just took my first 30mg dose yesterday. I felt ok at first but last night I started itching and I couldnt.. at about 6 am I felt real bad I started w anxiety and pain in my left arm and chest. And nausea also couldn't keep my eyes open.. I am discontinuing this med..i hope I'm ok after it wears off.. good luck to u

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I've been taking Hysingla for about 8 months now. I have very few problems with it and it seems to help my back pain. I do take Norco 5/325 twice daily for breakthrough pain. The one that I do notice is that it takes maybe 5 or 6 hours before the Hysingla starts to work. I pleased with it, taking it only once in 24 hours is a plus. I have no complaints. I wish you the best with this medication.

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Re: Tonya (# 37)

Where are you located? If you are around Fort Wayne Indiana area try United interventional pain center. Dr Kara he's amazing! He will get you on the right track.

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Was on hysingla ER 20 mg , Horizont ER 300 mg and tramadol for breakthrough for 6 months. The hysingla ER would get a fair blood level at the 8th hour and would cover my pain fair until the 18th hour. So I was having to go to the tramdol several times a day and running out way to early. Upped my Horizont , but was having cognitive problems and returned to the 300 mg dose. Just went back to immediate release norco instead of hysingla since it failed to cover my pain for the 24 hours.

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It was absolutely the worst med I have ever taken. Side effects were awful.

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My Doctor recently took me off 20 mg twice a day of OxyContin and put me on Zohydro 10 mg twice a day. The Oxy was no longer taking my chronic pain away even with taking 3 Norco 10s a day. Even though the Zo is 12 hrs and twice daily, even with the Norcos still having lots of breakthrough. Have an appointment with her this Tuesday and going to see if she will bump the Zo up to 15 or 20 mg. It is my understanding anyway that OxyContin is stronger than hydrocodone.

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