Hysingla Experience (Page 3)
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This is day 3 of me taking Hysingla 20mg after taking Norco 10/325mg three to four times a day. So far I've noticed some wacky side effects. The pill seems to kick in at around 8hrs, and I can't keep my eyes open, I get a rush of anxiety and nausea. I've taken EVERY other ER opiate in the world and none of them did this to me. I do notice that it has lessened my extreme pain already and I have taken a few norcos on top of it thru out the day, but the 8hr mark seems to be like a different world kicking in. Has anyone been on this for awhile, went thru these side effects and then came out the other end actually liking this med? I can find NOTHING on the internet regarding much experience or reviews out there on people who are taking this med. I've woken up in the middle of the night with abdominal pains, anxiety and an overall feeling of weird. Then it passes and I fall back to sleep, and I just feel so hungover. Also it's like every three hours or so it will ''kick in'' again with the can't keep my eye open thing, the nausea, etc. I started out the first two days not eating much (took away my will to eat) so today I made sure I ate a large meal before the 8 hr mark kicked in, but still feel so freaking weird! Please, can anyone out there give me some feedback?

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Hi I'm on my third day of hysingla er and I too get that neauscious feeling a few times a day. 30 MLG. I have severevRa and it does help the pain. I have to admit I do miss the euphoric feeling of regular vicoprofin but I was taking too many. So this is definitely better for me. I plan on sticking with it.

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I have just started taking this medicine. I was taking norco 10/325 4/day with tramadol in between. That worked great but my liver ALT started to inflate so they moved to morphine(which was horrible) then to the hysingla. For me, maybe my metabolism runs at a really high rate but it works really well when it first kicks in. Started taking it about 10pm so it works when I first wake up. It was the best I have felt when waking up in a long time. but it seems like in the afternoon it wears off for me (60mg er). So the evenings and going to sleep aren't as easy as they were with the previous regimen. Up to lnch it takes away most of the pain. It is really hard to get and more expensive than most medications. I have had pharmacists say they would not order due to the risk of addiction and abuse. I have had pharmacists say they would not order due to the obnoxious price it costs to get it (over $1000 for a bottle of 60 for the pharmacy to buy). I will be speaking with my DR on Friday to see maybe other options. Does anyone have any experience with vicoprofen and know if that may be an option?

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Yes I was on for 4 months with2 Percs for breakthrough pain hysingla is the worst drug I've ever taken for pain lost 13lbs ,malnourished depressed didn't come out of room didn't take pain away,mostly bone no muscle stayed in pajamas everyday !!! I will never take again try Percocet and maybe soma.i gained 5lbs in 7days since i stopped am happy already in one week .drink ensure or boost little walks food @ drink a lot of fluids.also couldn't sleep and couldn't go to bathroom.,and I was paying 35.00 a pill . Make sure you have some other pain pill on hand GOOD LUCK hurry get off soon. I went from 20 mg to 30 mg then when off 3 Percocets a day 2 norco hope you get we'll .

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I decided to stick with it, and it's been about a week. I still get very tired, but overall my pain level is so much better. I've stopped the nausea, I do get dizzy (orthostatic) when I get up fast or something like that, but all in all things are getting better.
I still have pain and need breakthrough, and I'd be very scared to up the dose of this stuff and go through that whole intro period again.

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I'm very sorry about the way you're feeling.

Hyslinga also contains Hydrocodone, just without the Acetaminophen and in a time released formulation. The FDA classifies this as a narcotic analgesic, so it has the potential to be habit forming and may cause side effects, such as nausea, dizziness, drowsiness, dry mouth and constipation.

There may be a change in the amount being released at about 8 hours in, which may be causing more side effects.

However, things should improve after 4 weeks, or so, as your body gets used to it. If your symptoms don't improve, or if they get worse, you should speak to your doctor as you may need to try a different medication.

Is anyone else on this medication that can chime in?

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