How Long Does Linzess Stay In Your System
(Newest replies first)

How long does it take for Linzess to be completely out of your system?

REPLY

REPORT

Re: Tootsie (# 47)

It gave horrible non stop diarrhea and dizziness. Took about 3 days for it to end. I have chronic constipation from opiate pain pills & neuropathy.
I do much better now just on 2 Dulcolax every 3 days, plus probiotic yogurt and bran. 1 tsp. Metamusil in OJ every night.

REPLY

Was this helpful? 0

Re: B (# 16)

This is my first day off and I feel really bad. I had a problem with IBS C now I am feeling terrible.

REPLY

Was this helpful? 0

Re: Diane (# 9)

I agree I took it two days. I quit because of the terrible side effects. Now I am nauseated and terrible headache. This drug may have its place for some people. It is poison for me.

REPLY

Was this helpful? 1

Lots of different reactions to this here, in my own experience is that it's caused headaches, general sadness and even hyponetramia but once armed with the knowledge of how my body reacts to it I manage to negotiate these things by taking 100mg magnesium at night and then I take 290mcg of Linzess around 7 am next morning with around 250ml of water then drink a couple of cups of sweet (using honey) milky decaffeinated tea which Seems to activate it (I'm not a breakfast person) and put 1 teaspoon of salt in hot water and take sips alongside my tea to replce the sodium I know I'm losing and it usually starts working around 1 hour ir so later lasts around an hour and a half or so then I can get on with my day though I do have to drink more fluids and salt water for an hour or so after. I also eat green veggies every day opting for frozen as its hard to stay sticked up on fresh veg daily due to logistics. Despite this rigmarole I'm usually ready to face the day by lunchtime and then eat and have some normality which I've never had with other meds. It's a strong med I won't deny it but it does work though from the replies in this thread I can see its not for everyone.
One tip for everyone here is for bloating and soreness I take a teaspoon of manuka honey after the effects have worn off and despite the cost its far better and kinder on the gut than any medication I've ever had. I hope this info is useful to at least 1 person, it's a pretty harsh med but can give some normality back once gauged for subjective experience and effects but it does take its toll if you're not cautious while taking it, just drinking lots of fluids isn't enough and dangerous as it will make your sodium, magnesium and potassium drop drastically in a short space of time.

REPLY

Was this helpful? 0

Re: Kimberly (# 17)

How long does it stay n my system
I feel I've been poisoned

REPLY

Was this helpful? 1

Re: Diane (# 9)

I agree with you. It's poisoning my body. Severe dehydration and nauseated for days, heart burn, etc. Quit taking it 2 days ago. I was prescribed 12/06/2023. I called CVS and reported Linzess. It has damage people's intestines. Bad reviews. I will call MedWatch and report Linzess.

REPLY

Was this helpful? 0

Re: Barbara (# 7)

I have been sick 5 days. Server dehydration and nauseated and smells. I quit taking linzess it poison my body. Explorted with my fluids watery came out. I have nothing left. I can bear lying sip water. Need help

REPLY

Was this helpful? 1

Re: Diane (# 9)

You say this without staying why? Please share what you know and nobody else does?

REPLY

Was this helpful? 0

Re: Farley (# 36)

I just started Linzess. I learned that depression could be a side effect or diarrhea. I am taking 290mgs, I am clinically depressed. So, search Linzess, you may want to change meds. I've had IBS pain all my life, I took muscle relaxers when the pain was unbearable, not everyday. Your heart is a muscle too, so I did not take it often. As I grew older they didn't work, so now I started Linzess. I think 290mgs is pretty strong. I will probably take it in the AM on an empty stomach and eat within a half hour.

REPLY

Was this helpful? 0

Re: Barbara (# 15)

Please tell me all this stopped finally. I’m having all these issues now and I’m very sick. Thank you!

REPLY

Was this helpful? 0

Re: AMTaylor (# 34)

I feel like my actual stomach hurts. I think this medicine makes everything in your digestive system off.

REPLY

Was this helpful? 1

Re: Farley (# 36)

Yes, I’ve been taking it for a month and I’ve had weird sadness. This drug has made me very ill, and I have had COVID, swine flu and the bird flu and this drug feels worse!

REPLY

Was this helpful? 0

Re: Kitkat (# 28)

I have been taking 290 mg a day for a month with no bad side effects, but it just isn't working for me. Does help with bowel movement and still have to strain to go.

REPLY

Was this helpful? 0

Re: Kitkat (# 28)

Linzess really worked for me after trying everything for over 20 years. Take exactly as directed and yes- lots of water. My only question is- as soon as I started taking it I've been having feelings of sadness/depression. I don't know for sure if it's linked to Linzess. I'm going to stop taking it for about a month and see if there is a correlation. It doesn't seem like there should be for that type of medication. I'm bummed because it has been a life-changing medication for my constipation issue otherwise.

REPLY

Was this helpful? 0

Re: B (# 16)

You lose so much water from loose stools you need to hydrate to stop headaches and dizziness.

REPLY

Was this helpful? 1

Re: Susan (# 32)

Was your stomach ache in your actual stomach or abdomen? I have been taking it for a week and my actual stomach hurts.

REPLY

Was this helpful? 1

Re: Healthy til Linzess (# 14)

The side effects do not occur in 100% of women. I have never had those side effects. It sometimes doesn’t work but I never had cold symptoms or dizziness.

REPLY

Was this helpful? 0

I’ve been on it for 4 months n now I have horrible stomach aches n look 4 months pregnant! I’m stopping.

REPLY

Was this helpful? 2

Re: NinaBaker (# 11)

I like Dulcolax much better. I take 2 at 3:30 AM, and I go at 9 AM. It is more predictable, and not as harsh as Linzess. I thought I was going to die when on the Linzess. It made me dizzy, and had explosive diarrhea and bad cramps. Never again.

REPLY

Was this helpful? 2

Can I consume fresh milk five hours after taking Linzess 145 MCG? Also, is it safe to have milk after taking Tamsulosin 4 MG?

REPLY

Was this helpful? 0

How long does this drug stay in your system? I was given 2 10mg pills in the e.r. They didn't work for pain, so I wa...

5 REPLIES

Just wanted to know how long before this drug is completely out of my husband's system? ## Revlimid contains the act...

14 REPLIES

My allergist had me take a puff of Symbicort in his office. However, when I came home and looked online - it is a direct...

3 REPLIES

I will be taking Levofloxcin 500mg for 10 days. How long will it remain in my system after finishing the medicine? ## Se...

115 REPLIES

I have been on pills before for like 8 months and my periods were normal and then I switched to Nur-isterate for 8 weeks...

1 REPLY

My sister is getting married on Saturday. I took a spoonful of Hydrocodone / Chlorpheniramine ER and was wondering if I ...

3 REPLIES

I'm currently nursing my 2 week old baby and woke up with a cold. I was wanting to take Theraflu and continue feedin...

4 REPLIES

My sister is in the hospital due to an overdose of Amitriptlyne. She had been taking 300mg for more than 25 years. She i...

2 REPLIES

I'm on day 5 of a Medrol 4mg 21 pack on day 4 I started having pain in my chest and left arm,days 1-3 I had pain in ...

4 REPLIES

I was wondering how long clindaycim remains in your system after taking it for about two days ## Hello, Laurel! How are ...

5 REPLIES