Harvoni And Confusion, Depression, Acid Reflux Side Effects

Curious, I've started my 5th week of treatment and am wondering if anyone has experienced similar side effects as me: Confusion, depression, crazy acid reflux, and mood swings...3 weeks left to go.

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Hello, Joe! How are you?

Yes, those can be typical side effects of this medication, along with headache, nausea and dry mouth, as reported by the U.S. FDA.

However, such side effects are usually transient and should go away, within a week or two of finishing our course of treatment.

Is there anything else I can help with?

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Hi Joe
I would finish your treatment! Your in the home stretch. I know the sides are bad...and I live with them still but I am virus free and that is important to hang on to in your battle to get well. I also did the 8 week plan and it worked.

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Joe you are doing really well, hang in there and if the going gets tough,,,remember you will be cured

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Yes fellow sufferers, I am in my last two weeks of a six month course of Harvoni and am finally free of side effects, I too suffered headaches, swelling lower back pain and waves of nausea...having asked my croaker about all this, she said "this soon will pass" small consolation when its you in distress...however, a few months of discomfort is better than full blown liver cancer if you don't pursue the drug...a as I'm sure we've possibly all known friends or family who've succumbed to the fatal cancer...I'm now hepc clear, but the next ultrasound and blood work in 3 months will be the disclosure of total freedom from hep c....here's hoping...just persevere and you hopefully will have a great outcome...a choice between the better of two evils....good luck and godspeed with your recovery.....

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My son had to stop taking at 6 weeks. He got severe depression an suicidal thoughts. It has been about 3 month's he has been taking wellbuturin for 2 months it is getting a little better but still has bad outburst that last the rest of the day about every 2 to 3 days. Wish you luck with yours.

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I just began taking Harvoni and I'm also on Adderall and I was wondering if anybody else has taken Adderall while on Harvoni? Also I'd like to know what side effects I may experience from taking the Adderall while on the Harvoni treatment.

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Hi. I take Vyvanse. I have 2 weeks of pills left, of 12 weeks. Missed a few cause of falling asleep and missed taking the pill.
I feel by taking Vyvanse I might have not had as severe fatigue, as if I weren't. More dry mouth, some days it seems Vyvanse doesn't work, other days, too strong.
Too many what ifs really to pinpoint. I have has alot of side effects.

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Anyone taking Harvoni experienced high heart rate of 88 to 98? I am on day 2 with Harvoni and everything else so far other than being tired is okay. I'm just concerned with Heart palpitations and high heart rate. Have some anxiety also. Any suggestions on how to bring heart rate down? I have hyponatremia and on limited fluid intake also. Thank you!

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My husband was on Harvoni for the full period. At times he felt tired, headache etc. He was glad that he was at home while taking it. I think with any particular Drug such as this one you will incur side effects. However, on the brighter side Harvoni has definetly cured my husband. The side effects disappeared after about 2 months. As he said, he is so very thankful of being HepC free!! I do believe that with a prescription such as this there is a risk however, if you checked every medication that your Dr. has given you, most likely you would not want to take it either. Give Harvoni a chance!! You will feel so much better knowing that you are not a HepC carrier anymore. After your cure, you go back in a year and have blood work done again, just to make sure that you haven't relapsed! I wish you much success, and much happiness when it is all gone. Good luck!!

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Will start Harvoni (90 day) treatment - What are the more serious side effects for the first week of taking this treatment?

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I just felt tired the second day with headache. I take mine in evening. The first week is a little brain fog, headache, some sleep problems. Nothing unbearable. Honestly now on day 13 I was crying just moody. Prayed and slept really good. Up and downs. Some days really good. I'm on day 19 and have more energy than I did before harvoni even though I had a sleepless night. The Dr. told me I could take B-12, C, D3 and baking soda 12hrs. before you take harvoni. She said I could take melatonin if can't sleep also. Most nights though I sleep well. Bless You! It's easier than you think. I've seen friends die of this horrible disease in such agonizing pain, this treatment is a TRUE BLESSING!!! If your tired rest. Have faith and don't dwell on it. It will only be a space in time before you are cured and give your body some time to get back to normal! (BIG HUGS)

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I'll be just taking Harvoni starting this Monday, all I can say is have enough to get you through *VALIUMS * Don't know what kind of side effects I'll have~(90)days of treatment!!!

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To your question about taking 'Adderal while taking *Harvoni *I would be thinking about your nerve system, especially having mood swings and problems sleeping ~Have your DR. Adjust.

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Everything is ok with my 'Post, hit wrong key which got Incorrect Text verification -Thanks for your concern *

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YES I Have and at 5 weeks. Got 6 weeks to go! Also breathing problems been in hospital twice! Almost admitted to ICU with trachea!! On oxygen and breathing meds.

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I'm(1)month and(8)days taking Harvoni Treatment, My side effects are waking up every morning @ 4:A.M. with a burning sensations in my stomach, I'll drink sum 've 8 juice then lie down to go back to sleep, but actually, I have to empty my bowls out before I start all over again at 12p.

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Side effects since being on,'Harvoni, (2)months out of 90 day treatment, has anyone experienced a burning sensations in their stomachs early in the morning hours, and had to drink something so you could go back to sleep?

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Shorty, I'm now going through 8WKS on Harvoni, my Side Effects has to do with highblood pressure, DR. put me on *Norvasc 5mgs once a-day to slow my heart rate, my last heart pressure was~'173/96- So I understand what your going through, I'm now Hepatitis free, have 5weeks to go, Was told even though I'm 'Hepatitis free, DR. Said that I have to finish the complete '90weeks to make sure I don't have a relapse. So far, my biggest problem is at night I wake-up around the same hour '5a.m. with slightly discomfort pain in my stomach, usually it goes away as the day goes on. I guess this is also a side effect taking *'Harvoni - just hang in there and finish your treatment, I'm sure you'll be satisfied with the results of this Medication ~ good luck with your treatment!

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Harvoni, It has been almost(2)months now, First month bloodwork showed that Hep-C virus was not detected, got (1)month to go,my sSide affects are burning in my stomach in the mornings until I relieve myself on the toilet!

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Harvoni Treatment, I'm now on my last 12week Harvoni Treatment, Having trouble with this last month of treatment with side effects of feeling burning sensations in my stomach, is this normal?

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I want to join a class action law suit against Gilliad. I have so many issues it's impossible for me to get them down. I twitch and cringe so much because of the pain I'm in I can't sit long enough to send out my side effects. I would love to talk to an attorney.

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Re: bill (# 44)

Had my final bloodwork done several weeks ago, 6-months post-treatment. The HCV is gone, undetectable. Have suffered stomach issues since beginning treatment which has worsened somewhat since then. Have been advised by my Gastro to undergo a Colonoscopy which will be done next-week. Initially, he wanted to perform the Colonoscopy before I began the Harvoni. When I returned to see him regarding the continued bowel-issues 2-weeks after my final bloodwork, he told me that he suspect's possible colon-cancer. He added that the Harvoni worsens bowel cancer which is why he recommended the Colonoscopy first. Unfortunately, he never mentioned that to me when originally suggesting the Colonoscopy. My wife believes that it's his attempt to 'rattle-my-cage' for not taking his advice initially. I know one way or the other by the end of next-week...

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Re: Scared Mom (# 5)

Hate to say, but I know people (post treatment with Harvoni) who have had suicidal thoughts, and others who have succeeded. Take it seriously. Sorry.

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Joe P
Yes, many of us have experienced those very-same side effects from Harvoni. Try to increase your water intake as it will help to alleviate them. Maintaining hydration is extremely important during treatment, which I found out late in my treatment. I was also losing handfull's of hair, which almost caused me to quit prematurely. Best of luck in your effort to regain your liver health and stay positive.

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I did go through confusion ( has continued) and problems with stomach. I did start getting headaches which has continued as well. The one that has been the most bothersome is being tired. That has continued as well. I feel fortunate that I was cleared of HCV, I have found the continued side effects to be an issue.

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Re: shorty (# 8)

Yes. I did expirience heart palpitations, high pulse rate-92 bits and BP up to 171! But my sideeffects started on day 1 of week 9. Please, be very careful with Harvoni.

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Re: Jeff (# 40)

you may have the resistant strain,,,epclusa will probably be the next drug, I hope you did not have the severe side effects some of us have had

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Re: John (# 20)

I took meds fasting at 7am along with my reflux meds. After 30 minutes I have coffee and about 20 minutes later I’m in the bathroom completely cleared out, lol. Lost about 8 lbs but now on my 8th week with 4 more to go. Some minor headaches and hair loss but feel good.

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I completed my 12 week therapy of Harvoni in late September but rather than scheduling my final Bloodwork in three-months as is recommended, my Physician scheduled mine to be done six-months later. So I won't know if the treatment has been successful for me or not. I'll post again once the final Bloodwork results are in, to share my success or failure to clear it once and for-all. I will not be treating again in the future, so hopefully it's done what it's been marketed to do...

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Re: Jeff (# 40)

Hi Jeff. I failed the Olysio/Sovaldi 12-wk tx. It came out just before Harvoni. They put me on Harvoni, right after FDA approval, but for 24 wks. I've been clear for coming up on 3 yrs. My liver was in 4th stage and my doc said that's probably why I failed the first tx. Don't give up hope. I'd suggest, try again, only for longer. Good luck.

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