Generic Buprenorphine 54 411 Vs M 924 (Page 4)
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I've been going to a clinic for almost a year now and each time I get prescribed 8mg Subutex. When I would fill my prescription I would receive 54 411 white tablets. Today when I picked it up I got M 924 white tablets. The only difference I've found is the manufacturer. The manufacturer for the 54 411 is ROXANE and for the M 924 is MYLAN. Are they pretty much the same pill just different imprint/manufacturer?

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161

I agree that I need to be off the Xanax but my OBGYN says don't try to cut down more than a half a milligram every few weeks and not to push it because I already went from 6 mg's of Xanax a day and 20 mg's of Valium to no Valium and now I'm down to 2 mg's of Xanax a day. It's the hardest thing I've ever done. I have major withdrawals super bad cramps and very moody and can't remember anything. It's horrible. The Subutex doctor said don't try to ween down while you're pregnant so I take about 1-1 1/2 a day.

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160

That is possible that they just didn't have it. I doubt they will do away with Subutex because they prescribe it for pain and they make to much money off of it.

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159

Thank you for your post. I live in South Florida. Just south of Sarasota, and for the last 2 months I have not been able to find any where I live. I have had to drive over an hour to Sarasota to fill the prescription. One pharmacist told me that they are trying to get away with Subutex all together and that is what the problem is. I was beginning to question whether these pharmacists were giving me the runaround because they just didn't want to fill the prescription, but because of your post I think maybe they honestly just didn't have it.

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158

I was on suboxone for the first half of pregnancy before switching to subutext. I was on less then 8 mg a day. My son is now 3, and never had any issues. My advice is cut down, and get off Xanax ASAP.

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157

I have been very upset at this so called back order because I have only tried two kinds of subutex, the little ones with the arrow that are complete garbage and the one from the roxane company! I was told the roxane ones are on back order and I was wondering if anyone has any news or can tell me if they are back! I live in west palm beach fl

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156

They merged with a company called West-Ward. The Walmart in my town has them again but the pharmacist told me yesterday that per the DEA when my doc faxes my script he needed to include a care plan stating when I started seeing him, if we're working on tapering, do I attend all apts & pass my UA's etc. Also they said they are not excepting ANY new Subutex patients. Idk if this is some new DEA policy for any pharmacy with the Roxane/West-Ward(54's) kind or if it's a Walmart policy. Either way I'm just glad there back cuz the Mylan(M924's) are HORRIBLE!!!

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155

Hi, my doctor did actually change me from suboxone to subutex, due to the cost in paying out of pocket/insurance

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154

The mylan ones are terrible and I have my Dr write Roxanne on the Rx from now on. They are different. I hope Roxanne is not discontinuing their version

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153

You're the only person I heard that prefers the small ones. I like to break my 8 mg pill into 4 pieces and it's nearly impossible with the Hi-Tech brand. The only few people I know that didn't have a problem with Hi-Tech are people that inject it. I'm really surprised that it works for you sublingually because I don't feel there is enough pill there to attach correctly to my opiate receptors. They just dissolve so fast and I think it takes double the amount to feel the same way. Just my opinion anyways.

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152

I have personally never tried the Actavis brand but have done the Hi Tech, Roxanne/West Ward Labs, and the Mylan's. The Mylan and Roxanne are the only good ones. I would also rather wait 3 miserable days than get the Hi Tech ones. They are truly horrible. I break mine into small doses throughout the day and with those you can't. Two of those don't equal one of the Mylan. It's horrible and you're right, I also wonder how this will affect people early in recovery. I have been off of opiates for 12 years and have been on Suboxone/Subutex ever since; and truly believe if I try to stop I will surely relapse. Especially since so many people in my town are currently dying still. You should be able to order any brand you want as long as you have a prescription and are willing to pay the price. It's crap! Something needs to change! The only people I heard say this medication doesn't bother them is the people abusing it. They shouldn't want people to have to feel like they should inj. their medication because that is one of the biggest reasons for getting and staying clean.

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151

Hello,

Thanks for update on the information from Roxane. I too just discovered that news about the merger /acquisition. It's really unfortunate that the ball was dropped on their end since all pharmacists I visited this past week had no information other than there being a delay, or some said they don't think Roxane would be back. (Partly correct)

Sadly, the Walmart I visited only had the 8mg tablets of the Westward brand (roxane) and their systems did not allow them to even order the Westward 2mg - nor anything else other than the Hi-Tech.

I really wish I had been asking the pharmacists to look into "Westward" this past week, but I only learned of it the other day. Too late for me.

Sadly, it came down to Activas or Hi-Tech for me for this month.

I can put it this way:

If I was out of medication and my options were to either refill with Activas right away, or go 2-3 days in withdrawal until another brand was available, I'd choose going 3 hellish, sick, horrible days to avoid another month of Activas.

Yes, I know people will say how idiotic that statement is and that if that was reality then there is no way I'd opt for 2-3 days without medication.

But having gone 30 days feeling so depressed, so empty, 24/7 headaches, irritated, tired beyond belief (a very different tired), hot/cold hot/cold, and tuly have ZERO desire to do much of anything -- including being around family, then I'd do what I could to avoid that.

I am truly, still amazed even after a month's time of how different that medication was for me. (My own experience)

It even led me to filing with the MedWatch program because I was so taken back by the mental effects of the medication, as well as physical. I really did worry for anyone else who might be early in recovery and was given Activas instead of another generic.

First time I had cravings in years was this past month....still scares me to think about that.

I thought for sure I was going to adjust to the change, but instead I felt like I was on an entirely different medication. Crazy too since I used to never, ever, ever think there could be such a difference between one generic and another.

If my experience with Activas is not unique, then I can see some real serious changes happening down the road with how "easy" it is for pharma to be approved for a generic for this medication.

I read much of their trials/studies since I became so curious about it. Without a doubt, the design of the studies to prove it's efficacy was so incomplete. I'm still amazed that Pharma continues to push the idea that 16mgs is a good starting dose.

It's unfortunate because it's so easy to place trust in our doctors and to also believe that such high doses are exactly what we need. It's only when others drop down to a few mgs that they realize how much better they truly feel -- and that they wish they had known how much better they would have felt long ago on a far lower dose than was recommended.

($$$$$$ why would a sales team for a company -- any company -- ever, ever try to push less product to vendors or distributors..... they don't, ever.)

So unfortunately the same has happened to Pharma and certain medications.

Which medications? Only those where the research into long term effects, efficacy of dosage, reactions to other possible concurrent medications, etc. is still in its infancy....

Just like any other new market, new product, or new change that presents new business opportunities in something where there is little data or not enough, the first ones to the plate with the most resources and influence are the first ones to shape the narrative.

That narrative sets the foundation for good or bad. Then it can takes years, even decades before the data, advancements in tech, and official standards begin to show how the early narrative was flawed...... but it will always be okay because the excuse will always be that there was a lack of quantifiable data to have been able to form better decisions about x,y,z at the time....

Always true, but also rarely the full story since data rarely incorporates greed and desire for power and control into the full picture.

Looks like the makers of Suboxone are right now in the middle of their early narratives being reshaped.

Unfortunately, without the Patients / People / consumers having the ability to play a bigger role in the narrative early on, this cycle will continue and people trying to gain control of their own lives will still struggle.

Sorry for ramble. I just wish there was more equity in all areas of our society. All areas....

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150

Ok boys and girls here's the answer. I just spoke with Roxanne labs. They went through a merger recently with West Ward pharma. This is what the customer service representative told me verbatim: "We can't make the pharmacies buy from us. For some reason they are telling people that the product is no longer available but it is 100% a free flowing product and still available". That's what she said and I told her that NO pharmacies anywhere in the 50 mile radius, which covers parts of two states, has them. She said she has no idea why and that it is definitely available and being shipped. She said there was a 2 day delay because of the merger but that it is 100% still available.

My hope is that she maybe is exaggerating the delay and that it was probably longer than that so the pharmacies had to go with another option for now. If that's true they should be available again by next month or so. That's my hope at least anyway because all the other generics I have tried do nothing for me and I have to take 2-3 times the amount I usually do. I read on another thread that someone found the 54 411 at their local hospital pharmacy but none of the hospitals in my area have an outpatient pharmacy.

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149

I don't like the small ones because I don't think they dissolve sublingually as well and I also don't like them because I like to break mine into pieces. I don't take the whole thing at once, I do it in quarters and the little ones are impossible to break into pieces. No one I know likes the small ones around here and we have an opiate epidemic where I live so everyone is either taking opiates or on Subutex or Suboxone. The only people I've ever heard that like the small ones are people that abuse them.

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148

I live in Tampa, FL. I'm sure you have heard all over the news about the opiate problem we have down here. I have been off of opiates for 5 years. I get Subutex sublingual 8 mg tablets made by Hi-Tech Pharmaceuticals; they are real small pills with a arrow on one side and 8 on the other. I used to get really big subutex and I couldn't stand sticking those in my mouth, it felt like I was eating a piece of chalk. So my pharmacist one day showed me these and I have been on them ever since and I love them. You barely feel like you have anything in your mouth and it only lasts in your mouth for maybe the most 5 minutes. Plus they are easy and convenient to take with you if you have to go somewhere. So I was just letting you know because you said you were looking for the bigger ones and that the smaller ones you didn't want to get messed up with. I've never been high off this brand. I just believe in the smaller the pill the quicker it takes effect, because it has less to get through your system. So maybe that's the problem and why she got sick? Maybe she should try taking half at a time. Hope that helps.

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147

I get the Mylans in West Virginia but they are very hard to find! They are very comparable to the ones from West Ward Labs. Those ones are also almost impossible to find. I also live on the PA border and they also don't have them anywhere.

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146

I've been searching everywhere for the Roxanne in my area which is south of Boston ma apparently a company called west ward baught them out and now everywhere is back ordered. I've taken the hi-techs which were awful now cvs has switched to a new brand called sun which I heard burns your mouth and also causes upset stomach, after the last time I switched to a new brand I wouldn't accept so I've been getting partial refills where I can find them but have only received half a month in a the pst month. I had to get a new script and now again am only getting a 2 day supply or
The 54-411's I've read about the mylan but no one in my area seems to distribute these. The activas don't work well either. Does anyone know inactive ingredients in the Mylan and Roxanne brands? Also what area are u getting the mylans?

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145

Yes they are the same thing I've been taking them now for about eight years I used to get the Suboxone strips when they're too expensive I lost my insurance now I get buprenorphine which is subutex and they are small pills with an arrow on one side and 8 on the other and they do the job just as well so don't worry you have what you're supposed to hope you feel better

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144

I got totally cut off of 4 mg's a day of Xanax and I'm 6 months pregnant. I didn't know I was pregnant my periods are irregular. Now I did the right thing and told my doctor and he cut me right off. I could have seizures or the baby could. I'm also on 16 mg's of subutex a day. I just pray this baby is gonna be ok. I've cut down to 2 mg's a day already but they say that's even to fast.

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143

It is very hard to find a pharmacy and I live by Pittsburgh and I called everywhere and the person getting them filled has a PA ID it's crazy! The only ones they have is them small ones they suck!

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142

Yeah the Mylan are good but I think the 54-411's the best made by Roxanne Labs.

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