Extreme Fatique, Joint Pain, Muscle Weakness With Eliquis For Afib (Page 5) (Top voted first)

I was having extreme fatigue, joint pain, muscle weakness after starting Eliquis and started to having black stool with nausea and abdominal pain. I gradually reduced the dose until no longer taking Eliquis nor ever will. It really put a fear in me. Asprin works for me via my AFIB. I can tell if my blood is too thick when my heart is working hard to pump the blood out of my heart. I feel much better when my heart is pumping normally when the blood is thinner. You sometimes have to insist to your doctor the side effects you are feeling, this is a fairly new medication. Anyone else have these side effects?

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Re: jazzy (# 48)

My dad is on Eliquis and Metoprolol. He has only been on it for two months now but has complained of leg weakness from day one. The doctors reduced his Lipitor down to 40 MG from 80 MG this didn't help. They refuse to take him off Eliquis and let him go back to an Aspirin a day which he was fine on for his A Fib the past 9 years. I will be calling them again tomorrow after reading all these posts.

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Re: RC (# 8)

I had many side effects such as dry mouth, sore muscles and joint pain throughout my body. I had been on it for only 4 months. I just quit because I could no longer deal with the side effects. I had a blood clot in my right lower leg. I am seeing a blood specialist. I would assume that he would put me back on another blood thinner. I prefer not. I will not take any of the newer drugs.

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Yes, major muscle weakness with fatigue can’t wait till I can stop talking this drug. Doctor does not acknowledge that it could be from the meds.

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Hi I haven't been on it long but I am tired, muscle pain and stomach pain. Am going to my doctor tomorrow so am going to tell him how I feel. Am going to ask him if I can take Cartia tablets instead of this tablet. Hate feeling so yuck.

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Re: David (# 73)

Unfortunately, most doctors have a tendency to discount patient complaints about side effects of drugs. Just keep after him or her, and let your doctor know you are not making this stuff up.

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Re: James (# 17)

Hey James, is there a natural herb to replace Eliquis?

{edited for privacy}. Thanks

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Re: Archie (# 51)

Since taking Eliquis,I have been gaining weight,dizzy,trouble sleeping and severe breathing problems. My doctor gave it to me to prevent strokes,but I need to stop. So glad I read these comments,I just wanted to make sure I wasn't just imagining all these changes in my health.

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I have been on eliquis for 5 weeks and have started experiencing pain in my right leg. I am worried about stopping it as I have clots in my lung. I have health anxiety so I'm really out of my mind.

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I hav noticed that my breathing as been much better can now go for long walks with my dog just wish the aches and pains would go away.

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Re: Pat (# 80)

I was told it's the clots that cause a lot of the pains I don't no if this is right or is it eliquis.pain in neck and top of shoulder and upper back anyone else hav this.

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I have a strong suspicion that Eliquis is the cause of my weakness and inability to no longer being capable of climbing steps. It really got worse when the dose was increased from 2.5 to 5mg. When you add to this the fact that I have been going to the gym 4-6 times a week for at least an hour each time for ten years. I still go but I can't even step normally off the curb in they gym without stepping side ways. I just finished 14 sessions therapy which the instructor had his doctor's degree. I still can't climb the steps. Doctor's poo-poo that it could be Eliquis that has caused the problem. They would rather tell me it's arthritis and my age and it is what it is rather tha explore other alternatives too Eliquis. As long as they don't spend more than 15 minutes they are happy. By process of limitations Eliquis is the place that changes should be looked at.

Solution...Don't get old!

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Yes I have had joint pain since starting elquis, but I have tried other blood thinners and this works the best for me since my problem is a clotting problem and not afib. Warfarin isn't for me as they have trouble getting my INR's stable. I have other symptoms from other blood thinners so I have to deal with this unless someone knows of an alternative.

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Re: JCH (# 5)

I had a defibulator implanted in 1999 and formed a blood clot. I was on warfarin for about 6 years, of course you have to get your INR's checked to keep you at a certain level. I had no side effects accept getting blood drawn. After 6 years no more clots they just put me on 1mg and I was fine. In 2016 I had surgery and developed 3 blood clots and needless to say they first put me on xarelto and it did not agree with me at all. My doctor changed me to Eliquis and since I have been on it I have had joint and muscle pain, tired all the time, and gained 20 pounds, without changing my eating habits. I found out that other people are also experiencing the weight problem. I don't know if I want to try any other blood thinner because I believe there will be side effect to any of them. I will have to be on this for the rest of my life and it really disrupts the quality of life. Has anyone tried any other blood thinner out there and had no problem?

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Re: Rob (# 82)

That is what the docs, unfortunately.........IT IS IN YOUR HEAD AND YOU ARE GETTING OLD. It seems that older folks that exercise a lot are more prone to the muscle issues. That is what I found.

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Re: Rob (# 82)

Eliqus I believe is the problem. I have no choice, since I am prone to blood clots, but just if I have surgery, so I am told I have to take 2 a day 5mg for the rest of my life. I have joint pain, tired all the time, I use to ride my bike 6 miles a day, or go to the gym, not anymore. I don't eat much, and eat healthy no fried or fast food for me, hardly any carbs, no surgar, and I have gained 25 libs since on this. The doctor says not a side effect, but gave a shout out and many replies with same problem. One runner gained 40 lbs. Do you have to be on this and nor Warfarin? I had no side effects when I was on Warfarin. It is a pain until they get your INR's straight, sometimes only a couple of weeks, and then get your INR's once a month. I would go back on that in a heartbeat.

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We Eliquis users need another pain killer besides Tylenol which is next to useless.

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I was taking aspirin & metroporlo for 7 years but I had a stroke on vacation. I was on vacation when it happened so went on pradaxa for 3 weeks, but the had severe heart burn. I am taking Eliquis now & I felt weird at first but I stayed on it & am doing fine now. I am 67 & so far si good.

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I was on Eliquis from July of 2016 to July of 2021.
I had many problems. March 4 I had aWatchman filter put in snd had to take Eliquis till end of June. I feel so much better. I am in permanent AFIB and take diltiazem 30m every 6 hrs. Had problems with constipation. Dr gave me 400m of magnesium. I also take one baby aspirin a day. I take iron and folic acid every day that helps me with the fatigue also B12.

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Re: Lexie (# 84)

Look into Natural remedies...Tumeric comes up as Number one...there are many more

Developed small clot lung after 2 week stay in hospital via Covid & Bacterial Pneumonia...
Increased my Eliquis to 5mg 2x day and have Extreme pain shoulder...arms neck...starting in back...
I need to resume to Aspirin and Natural remedies...
I too have gained 20+ pounds...Some due to Steroids but have been off for awhile...Think it’s the Eliquis...Dietary not helping...Can’t loose this weight.

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Re: Lexie (# 89)

Lexie What is INR???

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