Extreme Fatique, Joint Pain, Muscle Weakness With Eliquis For Afib (Page 5)
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I was having extreme fatigue, joint pain, muscle weakness after starting Eliquis and started to having black stool with nausea and abdominal pain. I gradually reduced the dose until no longer taking Eliquis nor ever will. It really put a fear in me. Asprin works for me via my AFIB. I can tell if my blood is too thick when my heart is working hard to pump the blood out of my heart. I feel much better when my heart is pumping normally when the blood is thinner. You sometimes have to insist to your doctor the side effects you are feeling, this is a fairly new medication. Anyone else have these side effects?

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29

I red your problems with ELIQUIS and I can tell you this is not in your head.
This drug was given to me just about 2 years ago for Atrial Fibrillation despite a cardiologist telling me my Carotid Arterial scan,Echo Cardiogram and 24 hour tapesx2 all fine.
G.P. thought it a good idea to prevent a stroke BUT I really wish I had never started on it especially since I suffer from Osteoarthritis with Spinal Stenosis Now Ive severe palpitations which I never ever had.!
Recently travelled abroad and I think there was an adverse reaction with this drug and the heat temperatures of 34-36 which have never bothered me before now back in this country[u.k.] it has settled down.
Always remember your time difference if you travel take it the same times you take it at home or you will mess it up.
I have severe joint pain hands knees and spine is worse on it.I also urinate much more and it seems to act as a diuretic for some reason.
Doctor who started it WILL NOT take me off it as she doesn't want me to have a stroke.
PLEASE never stop this medication by yourself and do Not take any n.a.i.s d like brufen. You must come off it gradually its a very dangerous drug and there is NO antidote unlike Warfrin .

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28

Yes my husband is experiencing fatigue and sleepiness

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27

I have been on elequis for two months and have had chronic muscle and joint pain. My whole body felt stiff. I am an avid golfer and after 9 holes I can hardley lift my legs to walk. I have experimented and gone off the drug for a couple of days and feel normal. I am now getting pains in my neck and pain in my jaw joints to the degree of difficulties in opening my mouth. Feel like flu symptoms. I stopped taking flecanide thinking this was the problem - this may have only increased the problem with the elequis. My doctor was not in favour of going back to aspirin . Still searching for a solution. I am 64 relative fit and did play 18 holes golf 4 days per week now struggle to play 9 holes once per week

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26

I tried Eliquis for two weeks and it was awful for me. I normally have no side effects with drugs, but this one gave me nausea, tiredness and joint pain. I went off of it four days ago and I feel much better today. It made my tongue feel weird and I had kind of a metallic taste, little appetite, in general felt strange. After my double knee surgery three years ago I had to inject a blood thinner every day for 60 days. There was no problem with stopping it cold. I am going to fight my doctor on having to take a blood thinner. If God has planned that I will die of a stroke, then nothing I can do in myself is going to change it. I take my other mess no problem but I am a point now that enough is enough!

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25

I had an Ablation done last month, they tried me on Xarelto and i could not tolerate it so i was put on Eliquis, been on it over a month. Side effects are muscle sorness,, muscles weak. Insomnia, going to the bathroom a lot. But i hope i will be took off of it this week. Don't never want to take another blood thinner

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24

I have been on Eliquis for about 3 weeks, after not being able to take, Xarelto, pradaxa or warfarin. I have Afib, have had 2 Ablation surgeries done. The Eliquis is causing me severe fatigue, Nausea, and diarrhea. Muscle pain, but unfortunately I still have to take it. However i do believe that an Aspirin every day would work just as well

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23

NO INR FOR ELIQUIS IT IS NOT REQUIRED HOWEVER ONCE A YEAR A BLOOD SAMPLE FOR YOUR RENAL FUNCTION IS TAKEN

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22

I was on Eliquis for almost 3 months. Think I slept at least 2/3 of the day because it kept me awake most of the night. Very bad bone pain especially from hips down both legs. Gained weight also, seemed to crave food even when not hungry. Headaches. All I wanted to do was curl up in a ball. No energy. Would begin to feel a little better as morning dose would start to wear off but then I would take second dose and curl up again. Also caused my stomach to hurt and I had trouble with BP and pulse increase. Dr took me off about a week now, beginning to feel human again. Not sleeping all day, have more energy. BP and pulse still elevating but feel so much better as the days pass. Hated that medication and the way it made me feel. It did what it was supposed to do I guess but so glad I'm not taking it anymore.

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21

I just posted in another thread about this very issue, and yes.. I'm bedridden now. Can't drive, can't cook, can't walk, can't stand to take a shower, nausea, severe pain in neck, upper body, arms, shoulders, so weak I need help walking or doing anything. And I've only just scratched the surface here. Going to call my cardiologist about getting the Watchman device so I can come off Eliquis and stay off. I was put on due to AFib, Atrial Flutter, and SVT (the last I'd had my entire life) and a TIA in 2013. My life is basically ruined and with NO quality of life whatsoever.

Eliquis is a scary drug. Be sure to contact the manufacturer and report your symptoms because that's the ONLY way they will take notice and let doctors know what the risks actually are. They also have to report the complaints to the FDA which may help in the long run as the FDA will be forced to report these issues to the public eventually.

Oh, I've been on Eliquis for about 2 years now and was, prior to taking it, a very active person who was still able to work, take care of myself, drive, walk, etc. I can no longer work.

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20

I have been fighting doctor for day's, all I get is dizzy, she tells me that is not a side effect, frankly, she's FOS, it's a rare 1 and I'm drug sensitive, call my GP, he said cut to 1 and take, at bedtime. I have a mitral valve leak due to be fixed on 6/1 and I can't life like this, any longer, stick a fork, in me.

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19

This is the most horrible drug that I've ever been on, all it does is make me dizzy and I never know when it's going to hit and then from there I turn into a wreck and go into a panic attack. I am begging to get off this drug and they won't but I called GP today and he said take 1, at bedtime. I have a mitral valve repair coming up on 6/1 and my life has been ruined with this drug, they tell me, go out, enjoy your life, kiss my grits, what's to enjoy when you have no idea when the merry go round is going to start.

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18

Get off it. Quit taking the doctor's word as f***ing gospel. They don't give a f*** about your health. They are in this business to make money. Take natural medications. I don't believe only a prescribed drugs made in a factory can treat, prevent & cure blood clots, that is BULL!! Tell you doctor you want to go natural and watch what he says, he will be against it because he can't profit from it like he does with them poisons like warfarin, xarelto and the like. I'm going against my doctor and going natural so I know how you feel. Trust!!

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17

Here is a solution go natural. Quit listening to them doctors, they really don't care about your health. They along with big Pharma are in the medical business to make money. No way in hell only a prescription drug made in a factory can prevent, treat, or cure blood clots. Cayenne pepper, garlic, ginger, water, fasting, nattokinase are among the natural alternatives.

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16

There are sevetal things to consider with ANY anticoagulant I had a massive saddle pulmonary embolism at the beginning of February. It recurred barely two weeks out of tbe hospital while I was on warfarin. I was taken off warfarin a month later because my INR was so unstable I had to have the tests done twice a week and it still yoyo'd between 1.5 and 4.5 (my goal level was 2.5-3.5 due to apparent unspecified clotting issues). I was miserable on warfarin, and I had the rare side effects, change of taste, numbness and tingling in hands and feet, and GI distress every time I took it. Warfarin has the advantage of an antidote with Vitamin K. It also has the disadvantage of taking up to 48 hours to INCREASE anticoagulant effect if your INR drops too low. It is slow-acting.

I've been on Eliquis for a little over a week now. I'm experiencing some of the fatigue and joint pain, though for me it is very hard to tell if it's a flare of my rheumatoid artnritis or the Eliquis. I've been off my Humira and methotrexate disease-modifying drugs since the pulmlnary embolism, so it could be that. Assuming it's the Eliquis, though, there are three things to consider. I'm at a very high dose, 5 mg. That can be adjusted to 2.5, which is the standard dose for most. Anyone taking 5 mg and experiencing side effects should ask if they can try the 2.5. A poster stated they were taking 1.5 mg, but I could find no information on that dose; in the US, at least, it is not offered. But if you are on a 5 mg dose, there is definite room to reduce.

The second thing to consider is that, yes, Eliquis has no antidote. But it has an effective duration of about 12 hours. That means if you do experience excessive bleeding, you have a short time before it wears off. To me, this is no more dangerous than warfarin, where a bleeding event would mean time to travel to the ER, be diagnosed, and receive Vitamin K. The 12 hr duration of Eliquis is also why you take 2 a day. If you take one a day, you are essentially bouncing between a coagulated and anticoagulated state every 12 hours, which for most of us would be very bad. Don't reduce to one a day...if you feel you must go off Eliquis without a doctor's assistance, then cut the pills and take lower doses, reducing gradually. I don't usually advocate coated pill-cutting, but the dosing info states it can be crushed (though crushed was given through a naso-gastric tube, not swallowed). At any rate, if it was administered crushed, cut should be acceptable.

Which brings me to the third point. Don't just stop taking Eliquis. Going off it cold turkey is associated with increased chance of DVT and PE above the usual risk when you stop taking an anticoagulant. With its short duration, you can transition to any other anticoagulant within a couple of days or go off it and not risk the increased clotting chance.

I have taken many, many medications over the yeats, many of them with severe side effects. All you can do is a cost/benefit analysis for you, personally. In my case, I am disabled and can't work. At this time, with pulmonary hypertension, RA, and risk of another PE, the side effects from Eliquis are acceptable, though I'll see if I can try a reduced dose. Everyone reacts differently to drugs...my dad has been on warfarin for ten years,and couldn't understand why I had so many problems with it. I love Eliquis in comparison. He threw a blood clot while on Xarelto. He loves his warfarin. Mileage varies. Your most-hated drug can be someone else's miracle.

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15

My husband has been on Eliquis for 6 months and had his pacemaker replaced in Nov. at 70 he has been very active until he was put on this drug, thought it might be new pm but now thinking its Eliquis. He has no energy and his legs have gotten so weak and are tired& heavy. Will call to get it changed, if possible.

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14

I had been taking Eliquis for a week and then I had severe nausea and severe weakness. I have blood clotting problem. I was taking just 2.5 a day. My doctor had me to take 2 a day. Glad I didn't take the second pill. I am still feeling weak and have joint pain.

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13

Yes. And my energy level is zero with eliquis. Will see dr again very unhappy

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12

Hi RC , think you may need further advice from cardiol as I was taking cartia daily to stop risk of stroke as suffer from a/fib. I have had a dual lead pacemaker put in back in 2014 which helped and continued with cartia until last Sept when I had a mini stroke, after this I was started on Elequis as told cartia not strong enough to thin blood anymore, this was advised and reason being if had mini stroke on cartia the risk is now to high for more serious stroke hence the elequis now which is 1 5mg dose twice daily. Luckily the mini stroke had no effect except a bit of loss of vision in right eye for about 15 mins. I have been as said on the elequis now for nearly two years and exercise reg, no pain anywhere, sometimes a bit of fatique but nothing I feel is out of the ordinary for my age of 66.. hopefully you will get some positive advice from a good talk with a good cardiologist, I hope you can enjoy your life kind regards, Johnb

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11

I have been on eliquis for over a year. I have had 2 heart ablations and on blood pressure meds also. I have severe pain on the left side of my back and down my leg. What can I take for pain besides Tylenol? It does not help much. I purchased nonrefundable trip tickets. Need some help.

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10

What to do for muscle weakness when taking eliquis

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