Eliquis: Stomach Pain, Abdominal Swelling, Bloating, Gas (Page 3)

Updated

Have been taking Eliquis 5 mg 2x day for almost 3 months. Seem to be having Stomach Pain, Abdominal Swelling, Bloating, Gas, Facial Swelling and lots of weight gain and water retention. Also brain fog and memory problems. (It's hard to tell how much of this is from Eliquis and how much from CHF associated with A-Fib. Also taking Beta Blocker and Digoxin.)

Eliquis has been out long enough for the pharmaceutical company (BMS) to put out a REVISED list of side-effects, to reflect real-life patients' experiences. Wonder if they have done so, or when they'll do so?

Am probably going to switch to Xarelto and stop the Eliquis, in hopes that the Xarelto will cause fewer problems.

82 Replies (5 Pages)

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41

I hated Zorelto and i do hate eliquis. The same. Eliquis is more of astomach issue than zorelto. On the eliquis legs feel heavy . Tingly sensation something running up the foot feeling is slightly less, has anyone switched from zorelto to. Eliquis and will insurance cover if you go back to zorelto. Eliquis i am waiting for somekind of approval!

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42

I am on Eliquis twice a day. And just recently I have had unbelievable stomach pain thought I was having an appendicitis. The pain has now settled on my right side hurts when I lay down and try to stand up.i have general abdominal discomfort and hope to get off med soon !

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43

Exactly the same symptoms for me.excessive gas and stomach discomfort. Slight diarrohea.

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44

I have had 1 major a fib episode and was put on sotalol. Later, after a Doppler showed soft plaque on my left side was put on xarelto. The xarelto caused my liver enzymes to jump 4x so switched to eliquis. I have had a lot of lower abdominal pain, bloating, weight gain, gas, and constipation. I am ready to chuck the lot in and take my chances. Feel like a guinea pig for drug companies.

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45

I've been on Eliquis for about two months, and all day long, I don't know if I'm going to fart or crap my pants. It could also be the Metoprolol, or I'm getting a double wammy.
Can you take any over-the-counter anti-gas medications with these drugs?

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46

I am taking 5 mg tablets of eliquis twice daily. Can these tablets be cut in half to take the 2.5 dosage? I've read where the can be crushed,so I'm assuming they can be halved.

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47

I have been on apixaban for just over a month now and my IBS does seem to have got worse also get tired don't seem to have any energy but not sure if that is due to lungs not working properly

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48

I've been on Eliquis for about 4 months, I have lower hemrorid bleeding.The hospital gave me a Colonoscopy which came out ok, but now my hemoroids are bleeding again. I'm taking prescription Annusol again. I know the bleeding is caused by the blood thinner I'm on. Any suggestions

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49

I have been on Eliquis 5mg two episodes a day and sotalol 40mg twice a day for a week. I have blown up like a balloon. My gut is bloated and tight as a drum. Definitely farting more. Seem to be retaining fluid all over. Face swollen, legs, belly, can't get rings on. Total disaster. Feeling miserable...I am 50 and have had a couple of episodes of AF. Other meds also disagreeable.

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50

I've been on Eliquis for 3 weeks now and I'm very very sick. I get gas but a lot of burning and bloating. The doctor prescribed Pepcid. Originally I was on Xarelto and broke out in a rash and also had stomach upset. So I was switched because they were afraid of allergies. One step forward two steps back. I don't even know how they approve these medicines from the FDA with so many side effects, but we're between a rock and a hard place and we need to avoid clots, so this is what goes on.

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51

Re: Afibber (# 2) Expand Referenced Message

I was on Xarelto for few days, and started bruising a lot and also spit up blood. My friend warned me about Xarelto and said she had a lot of bleeding and issues on it. So they switched me to Eliquis and although I have a stomach ache not sure if it's from Eliquis or not. Hope it works for you.

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52

Re: Harley (# 15) Expand Referenced Message

I tried the Zantac one twice a day, and it worked for me. I was so nauseated with bloating and dizziness. My oncologist had me try Pepcid. It didn't work. I saw your post, and I am so glad I did. I hope this helps someone else.

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53

I've had occasional arrhythmia since I turned 40. Occasional A-fib. Basic meds for that = once daily Micardis and bispropanol. Active, male, age 75. Fall '16, I started with what the GP said was asthma. In December '17: it was bronchitis. April '17 hard to function, severe shortness of breath and hours long bouts of irregular heartbeat. Finally, figuring I'm at death's door I pushed for more tests. MRI w/ intravenous indicated Multiple PEs. Started Eliquis 2 X 5mg per day. Took about 1 1/2 months before breathing properly returned. Arrhythmia stopped (except if I eat anything with soy flour.) I was 179lbs (5'10) in April '17. Three weeks after starting Eliquis the lower abdominal cramps started along with the flatulence...terrible. And finally The Taste, a metallic sour taste which nothing gets rid of. The taste is steady to the point where it overcomes or distorts the tastes of everything. Between the gas, cramps, and taste I have lost interest in eating. Even plain water "tastes" terrible; and my sense of smell has become heightened especially of anything burning... Being male I can only imagine morning sickness but I sure seem to have all the symptoms (LOL). The gas I can cope with, but The Taste, well I really find eating so unenjoyable that I eat only when necessary and only food as bland as possible. Five months on Eliquis and I am now 165lbs. From what I've been told by three MD's Eliquis is currently the best solution. Pity, for I used to really enjoy food. I guess The Taste is proof that I'm still here, breathing properly, and as long as I avoid soy, no more irregular heart beat. Mds say in Oct 17 I will be able to reduce to 2.5 tabs twice a day. Perhaps The Taste will stop or at least not be so overpowering...oh oh (pfffft... burp) there I go again. Question: Why doesn't Eliquis mention this in the blurb which accompanies the meds?

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54

Re: David (# 3) Expand Referenced Message

Have been on Eliquis for 3 months now and have developed ulcers.. My Dr. said this is not what caused the ulcers but I know it was.... Had to have a procedure and went off the Eliquis for 5 days and my stomach felt better.. But after the procedure went back on this med and severe stomach pains started again... Now on Meds for ulcers... Taking the Eliquis for Afib. Don't know what to do.

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55

I have been on Rivaroxaban for a month and I have a dry cough it drives me nuts.
Bloating is the other side effects .i was diagnosed with clots on my lungs .im now on 20 mg once a day from yesterday which I was on 15mg twice a day.
I'm seeing my GP on Tuesday as I can't go on with this cough and feeling down.
Does anyone else on this medication get this cough.
I saw a Haematologist last week and she said the clots doesn't cause the cough .
All my ultrasounds in hospital came Back OK.

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56

Yes, eliquis does upset the stomach. Can an anti acid be taken with the eliquis

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57

Eliquis is making me sick with an upset stomach, nausea and a general yucky feeling. How long after I stop will I feel better? I've been taking it for nine months and plan on stopping for a colonoscopy and endoscope. I will not go back on. What alternatives to Eliquis are out there?

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58

Re: Carolyn (# 49) Expand Referenced Message

Update: I am off the Eliquis and all meds for arrhythmias. I am finding that controlling reflux prevents the arrhythmias generally speaking. No more fluid retention once off the Eliquis. I feel like I need further investigation for abdominal issues like ulcer, hernia etc., but the docs aren't listening to me!

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59

Re: rodger (# 48) Expand Referenced Message

update, after almost 8 months on Eliquis, first 5mg twice per day, Second 2.5mg. twice per day. I still have some Hemmoroid bleeding and stomach discomfort. My blood doctor tested me again for the clot in my leg. the test showed it was still some clot remaining in my right leg. He said even though the risk of occurrance remains, and is only 5%, The risk out ways the benefit of discontinuing the drug. He recommend staying on the 2.5 mg. 2 x day. until further notice, or if I have heavy bleeding. The bottom line is do I want a stroke or heart attack if I stop the Drug.

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60

Eliquis gave me extreme gas and bloating. Second time trying it. Gave up. Also, the expense was way out of my reach...sorry didn’t work. Back on Coumadin

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