Clorfeniramina Maleato Side Effects

How long does the medicine last in your system? What are the side effects of this medication?
Can it be mixed with any other medicine such as tylenol, advil or excedrin?

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Hi Carlos,

Chlorpheniramine is reported to be the active ingredient in Clorfeniramina Maleato.

Chlorpheniramine has a half life of 21-27 hours; meaning that it can take roughly a full day before the last dosage you took is cut in half. Most pharmacists consider 5 half lives (5 days in this case) to be the average time frame it takes to leave your system. Keep in mind though that higher half life values ranging up to 43 hours have been reported. In cases like this, the drug can take as long as a 10 days to leave your system.

As far as side effects go, the most common ones are listed below:

• drowsiness
• dry mouth, nose, and throat
• nausea
• vomiting
• loss of appetite
• constipation
• headache
• increased chest congestion

More serious adverse effects can include:

• vision problems
• difficulty urinating

And to answer your last question, there are no interactions found between Chlorpheniramine and any of the drugs you mentioned (tylenol, advil, or excedrin). I've actually seen different brand names that have a combination of Chlorpheniramine + tylenol; etc.

Does this help to answer your questions?

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