Citalopram Manufacturer Change (Top voted first)

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Mail order changed my citalopram manufacturer from Amneal to Aurobindo. Have noticed side effect after the change. Should this be happening? Anyone els have this issue with manufacturer change?

124 Replies (7 Pages)

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2

I have to specifically request Auribindo, as whenever I take Amneal, it is like I'm not taking ANY citalopram at all. Does anyone else have this problem?

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10

I found Aurobindo the best. I was given another manufacturer and felt anxious and depressed. One doc said there should be no difference, while my first doctor admitted there could be a different effect neurologically because of quantities of binding agents and standards within the factories.
ITS NOT IN OUR IMAGINATIONS, THIS NEEDS TO BE ADDRESSED, THERE ARE SOME SHODDY MANUFACTURERS OUT THERE - avoid the circular tablets, the oval ones seem to be better - !!!

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8

OMG -- it's so great to hear others have the same troubles.. I *JUST* figured the problem out. I have had THREE weeks of acute anxiety, panic attacks, night terrors and wild mood swings all because someone gave me a different manufacturers pill! I honestly thought I was going totally bonkers. I can’t sleep. I had NO idea this sort of thing could happen.

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9

Yes, I too need the generic celexa by Aurobindo! I have taken it for many years but when they gave me a different generic it was like I was taking nothing! They said that ALL were the same, but I can assure you they are not. They may have the same "active" ingredient or whatever their argument is, but until I got the one made by Aurobindo again, I was very depressed and was going back to the doctor to find out what was wrong with me. As soon as I found the Aurobindo again, I was fine.

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5

Hi just left my doctors feeling foolish when I tried to explain how a change in brand had given me a severe light head and left me feeling exhausted and flat . The change in brand was from generics (uk) limited to aurobindo ... I was frustrated and upset and felt that I was being patronised with his explanation that the ingredients were the same, therefore a change in brand couldn't possibly be the cause of how i am feeling. But he couldn't explain why I had the symptoms but gave me a new prescription, which I have just collected . I would be interested to hear from anyone with similar experiences ?

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1

JC - I haven't been taking this med, but i wanted to share with you that it IS in fact possible to experience different effects between generic manufacturers. Even though ratios of active ingredients are supposed to be the same, the inert (inactive) ingredients are allowed to differ by a certain margin. Not to mention different manufacturing standards / facilities / etc. Sometimes if you mention this to your doctor or pharmacist, they can try to obtain the product from the other manufacturer, but this does not always work - it's all about supply chain and sometimes a specific manufacturer has a temporary shortage, or another manufacturer offers better prices to the distributors. I hope this info is helpful. Please feel free to share any other details about your experiences. I'd also be interested to know if anybody else is having issues with the Aurobindo product??

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6

I thought this was my imagination: I have been taking citlopram 10mg since beginning of Dec 2011 and the course ran out mid Feb; I got a new perscription which was in a different coloured box and I literally noticed the difference overnight; I felt like I was right back where i was before I went on the Citlopram. I am going to see the Doctor this week and ask if I can get more of the original ones - unfortunately I dont have the packaging for the manufacturers name of the original ones but I have for these new ones. A few weeks on and I dont feel any benefit from the new dose and I'm reluctant to up the dose as the 10mg were working fine untill the very day I changed brands. Would be interested to here more from others who noticed this.

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28

I was jittery for about a week after changing from Teva to Mylan. However, the Mylan is working great! Maybe even better then the Teva brand.

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4

I too have been taking Citalopram for several years. One manufacture worked just fine and I was having no issues or relaps of depression, but when they changed the manufacture I could obtain, my depression came back. The pharmacist told me that "they are the same" and made me feel that I was just imagining it...I talked to my doctor and he believe that manufactures CAN make a difference in the way it affect you. Try to see if you can get your pharmacy to get the previous manufacturer, but if not, your doctor may have to increase the dose to make it "work again". Best of luck.

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7

the aurobindo citalopram are complete crap. i feel lethargic all the time regardless of the amount of sleep i get. switching back to amneal asap

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12

I had the SAME thing happen to me, only the "opposite" manufacturer. I have ALWAYS had the ones made by Aurobindo. When the pharmacy changed mine to a different manufacturer, it was if I was taking NOTHING at all!! I even made an appt with my doctor thinking the medicine had stopped working for me and I couldn't figure out WHY? I made a few calls to various pharmacy's and once I got my Citalipram/Celexa by AUROBINDO again, I was fine. I have seen many posts that said the same thing, however, I have also seen the opposite, such as your message stating that you were on a different manufacturers Citalipram and when switched to Aurobindo, you suffered the same effects as I, because they changed the manufacturer. It is NOT in your mind. Doctors and pharmacists will ALL tell you they have the same "active" ingredient as if we are CRAZY or something, but we are not. It DOES make a difference. My brother is experiencing the same thing with his PAIN meds. If they give him a different manufacturer brand than what he has always taken, they give him no relief from his pain. My advice is to call around to various pharmacy's and find one that carries the brand that you always have taken. IF they don't have it, ask that they order if for you. Some will and some won't. Don't know what I am gonna do when "NO" pharmacy will ORDER me the brand I am used to taking for all these years. Will have to switch to another medication if that happens, because the ones made by AUROBINDO are the ONLY ones that work for me.

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26

The difference isn't in the medication for treating the symptoms (or rather it shouldn't be) However, I have found that the issue is with the inactive ingredients. Each manufacturer uses different inert ingredients. I have been on Dr. Reddys and now I have to switch.

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114

Re: Roy (# 1) Expand Referenced Message

Actually there is some difference in the active ingredient. I have read that the FDA allows concentrations from 80 - 125 % and still considers them “standard”. They say statistically there is no difference. The official scientific studies may draw that conclusion, but real-life usage does not bear that out.

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3

You are not imagining it -- I have had to switch generic manufacterers several times with my tramadol prescription for fibromyalgia. This last week the "good" brand (Mylan) which has worked very well for me, this time gave me a scary reaction. I am asking my dr to allow me to try compounding in order to avoid the ingredients that cause this reaction (which I have experienced with other generic prescriptions that I had been taking successfully) -- if I can figure out what it is!

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11

I thought I was losing my mind! I've only been taking the meds for about 2 months and my first batch was tiny oval pills (20 mg that I cut in half). The new ones are round and twice the size and I have felt awful! I assumed I was needing a higher dose, which I didn't want to do because I am slated to titrate off the meds in January.

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17

Aurobindo's citalopram also seems to the only one that has worked for me, but my pharmacy now tells me that it is no longer available (not being manufactured any more). Does anyone know if this is true? Or know any sources where it still is available? Or has anyone who previously found aurobindo brand to work found another brand that works for them?

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18

I had been told by Walgreens and just about every other pharmacy around that they no longer could get the Aurobindo brand, however I do have ONE pharmacy in our area, that still orders it for me. I don't think it has anything to do with "availability". I think it is the pharmacy chains that perhaps decide to go with another company for a "cheaper" generic, and say they can't order it for you. The pharmacy I get it at now, is a family owned and operated pharmacy, so they do what they want. Aurobindo brand of Celexa is the "only" one that has worked for me. Will have no choice but to switch to another drug when I can no longer get this particular brand.

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22

I am sure you will see there are others that have had this same problem. Personally, I PREFER the Aurobindo brand, as other generic brands I have tried do not work for me. But I have seen others that took another generic brand, that have said when they are prescribed the Aurobindo brand, it doesn't seem to help them. I don't know if it is because we have become accustomed to the brand we were always prescribed, and notice a difference when prescribed another generic, BUT it is not just in our minds. So, my advice would be to ask your pharmacy to order the BRAND of generic you have always taking. Maybe they will order it for you, or you may have to change to a pharmacy that will.

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30

There doesn't seem to be any one brand that works best for everyone. Aurobindo is the only brand that works for me, but other people find that it doesn't work for them at all and a differen tbrand does. So I guess the thing to remember is that if one brand doesn't work well, a different brand might work better and try a different brand before giving up on citalopram overall.

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31

The Amneal to me was like taking nothing, but everybody's system is different. I have been on Amneal, Teva and now Mylan.

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