Can I Take Methadone With Adderall?

Can you take Methadone while being prescribed Adderall?

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Hi Danny,

Based on my research there are no drug interactions found between Methadone and Adderall. This does not necessarily mean no interactions exist, but my sources state that every effort has been made to ensure that the information provided is accurate.

On a side note, there are interactions found between certain foods or drinks and both of your medications:

Regarding Methadone, it states that co-administration with grapefruit juice may increase the plasma concentrations of the drug. (So you'll want to try and avoid drinking this when your taking methadone).

Regarding Adderall, it states to generally avoid alcohol, as it may potentiate the cardiovascular effects of amphetamines (although the exact mechanism of interaction is unknown).

I hope this helps!

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I suppose I am the Guru of 'sorts'. That being said, I have survived the gamut of all extremes of opiates and amphet's. I'm currently on 120 mgs of Methadone (a blessing from the Lord!) and at the same time also on 30 mgs of Adderal which I usually taken up to 120 mg daily for a full blown 'battery charge'. That being said as soon as hr 22 > are upon me I am getting very irritable so I take 40 to 60 mg Methadone. To my horror, absolutely no effect is gained from this which is leading me to believe that Methadone and Adderall are competing for the same receptor sights. I have to end up either taking close to 100 mgs Methadone at once to try and relax or some Xanax if I can get my hands on some. If nothing relieves my hype, I get to bounce of the walls and go nutz! There has to be a connection between Adderal / Methadone receptors

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I am currently detoxing from methadone, and I find that adderall takes away the pain and depression and other various side effects from the methadone withdraw. I know adderall is addictive, but could not possibly be as addictive as opioids. I'm currently on 25 mg of methadone. I take it at about 9 AM, and around 5 or 6 I start to get hot flashes and feel depressed and have pain everywhere. At this point I take anywhere from 15 to 30 mg of adderall and about 30 min later I feel like myself again, and actually have motivation to clean and work. So I too believe that adderall effects the same receptors as opioids, just not quite so much. Hope this info helps someone.

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PPl, I think taking a CNS with your narcotics is a viable option for some. I take 200mg of done which I split, usually. 30-70mg vyvance and 60-10mg dextroamphetamine in a thirty day period. Along with that I use about 1gm of methamphetamine a week. This would be too much for most, but I'm 60 yr old. Been a poly drug user for fifty of those. I was seriously injured in the BOP. Was misdiagnosed for 8yrs. My right side(upper)is wasting away. C1 thru C7 plus T1 & 2 all shot. Our med. system is a joke. Sorry...the bottom line is CNS's & Narcotics do work well together and allow me to function. Lots of info about the combo around going back to the 50's. I believe you need sups. to help your body produce...Don't count on anyone but yourself. Learn. The WEB is a wonder. Use it./luck/don
ps. always keep some benzo's around in case...use as little as possible. Think Val's and Clonies are the most ap. because of muscle relaxing prop.'s. BP med goes along in sup. cat.\Clonidine .

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Thats exactly how i feel except im on 40 mgs of methadone and and 80 mgs of adderall a day and adderall helps me detox off the methadone if needed but if I take them at the same time I feel higher than a kite..

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Does Anyone Know what can take away the HOT FLAASHES from not having
Methadone in your system.I am trying to stop taking it ,aand it is very uncomfortable.

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Be careful with methadone on any mg. Even if you have a high tolerance for short-acting, long acting opiates and stimulants(remember also, certain stims differ, Ritalin is a NE and Dop reuptake and transport blocker, Focalin seems to be a "duel mechanism" reuptaking both dopamine, norepinephrine, but unlike Adderall doesn't touch even slightly serotonin. Adderall is more of a releaser. However, methadone, is extremely potent if never taken and one never knows(even though chances are, low dosage of methadone won't hurt, kill,etc.. mixed with Adderall) please..be careful.

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I,take 60mg of methadone also 60mg of adderal a day.I absolutely have no problem with neither of them.the only part I don't like from the amphetamine is when they make you feel like you took about 15 mini thins you feel like you are on edge.so that's why I take a klonopin to make that feeling go away.these two drugs help me stay focused through the day they make the anxiety go away also the depression,my social skills 100 percent better.Now on the other hand if I didn't have my amphetamine there is no way I can focus.its time to go night night.So basically I see nothing wrong with taking amphetamine with methadone.Don't let it control you make sure you control it.Also one other thing make sure you take some type of Benzo with it it will help take the edge off.

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You can't just stop taking methadone

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Dan,
Regarding methadone, if someone has been on it for relatively on a few weeks(3-4) than a one week taper can be effectively done, depending ofcourse of many factors such as the dosage(whether started on and remained with the 20mg range for chronic pain, or using higher dosages to titrate because of opiate detoxification reasons. Also, biological and socioeconomic stress factors play a role psychologically too) If you went for three day intervals, for example tapering off 20mgs using the following method: taking 10mg in the morning, 10mg at night, than went to 5mg am, 10mg for three days, following 5mg am 5mg at night, and finally 5mg for last three days down to nothing(again, based on factors mentioned above along with ones system and whether their CNS along with peripheral has been through withdrawals for example of other strong binding opioids in past. That could compromise someone to have to taper off a bit longer. Also, clonidine, hydroxyzine along with gabapentin or even lyrica short term use all in conjunction may be very beneficial in a faster taper.

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Dan,
Regarding methadone, if someone has been on it for relatively on a few weeks(3-4) than a one week taper can be effectively done, depending ofcourse of many factors such as the dosage(whether started on and remained with the 20mg range for chronic pain, or using higher dosages to titrate because of opiate detoxification reasons. Also, biological and socioeconomic stress factors play a role psychologically too) If you went for three day intervals, for example tapering off 20mgs using the following method: taking 10mg in the morning, 10mg at night, than went to 5mg am, 10mg for three days, following 5mg am 5mg at night, and finally 5mg for last three days down to nothing(again, based on factors mentioned above along with ones system and whether their CNS along with peripheral has been through withdrawals for example of other strong binding opioids in past. That could compromise someone to have to taper off a bit longer. Also, clonidine, hydroxyzine along with gabapentin or even lyrica short term use all in conjunction may be very beneficial in a faster taper.
@Lollipop-Regarding Adderall with methadone, one is a CNS stimulant, the other a CNS depressant. They don't have cross tolerance, but again, every individual differs. Have to take into various things such as tolerance, if someone has psychological related issues, psychosis, and many other possibly not fully consciously aware of which(although very low probability that someone wouldn't already realize they were suffering from a specific type of disorder) triggers mania, anxiety,etc.. However, I do disagree with the use two CNS depressants like clonazepam with methadone. That is dangerous(again not for all, but those who are not tolerant, have never taken both or one, along with the fact you now are dealing with various different neurotransmitters being potentially compromised, leading to minor side effects, to severe, to none many times. Always use precaution, know theyself:)

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Dont take so much adderall and youll be fine.The key to methadone is stability
Do everything the same every day.Any little changes to dose of any drug your taking
will bring on some withdraw symptoms..

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You can just stop taking methadone. I was on 80 mgs a day for three years and decided I didn't want to depend on something anymore! I did it cold Turkey! It was very hard! I couldn't sleep, had withdrawals pretty bad. But you will not die! You just need the will power!!!

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Im on 60 mg of methadone a day and its been a blessing for me as well. I noticed that you said you take zanax with methadone. I have had a few friends die from that combination. The two drugs mixed together will shut your respiratory system down especially taking over a 100 mg of methadone. If I were you I would decide which is more important not withdrawing from opiates or anxiety atacks. If you keep taking both you wont have to worry much longer about either. Good luck. Ask your doctor about the combo.

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that is definitely not true it is dangerous to take both IF you are not taking these medications the right way or under a doctors care some people such as myself really need that medication

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I taken 160 mg of liquid methadone everyday for 10 years I can hardly feel it after 10 years at the same dose. When I wake up in the mourning I feel very sick till I dose to give me some energy about 4 months ago I started taking 15 mg of Adderall instant release .At first the combo worked great but now I feel great for about 4 hours then I feel scared nervous weak very sad how do I get out of this mess if I don't take the Adderall I just want to sleep have no energy talk very little feel sad not sure if it this bottle of genric Adderall or my brain chemistry or what but i can't go on like this I don't know what to do.

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will Adderall decrease my steady methadone dose:?

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Ive been on Methadone for three years and I have tried the detoxing at once and that's not a bright decision. However a lot of people that have been on it as long as I have know that they usually gradually go from a powers dose to a higher dose over a period of time. So the best knowledge to give to someone trying to detox off of methadone would be to taper down every four days one mg that way you get off of it the same way you got on it and it's more likely goin to be a successful detox without the Sweats, Pain, nausea, possible vomitting, etc. however to me if you have just been on a low dose and no higher than 25-30 mg then more than likely your goin to take a lot less time and effort to detox but using the same route. Get a scale that weighs your mg and put ur meds on there weigh it take 30 like your normal dose next week weigh it to 20mg taking 1mg off your dose maybe 2mg depending on yourself N your drive/motivation and just go from week to week and when u get down to 10-12 mg start weighing every 9 days that way your body can get used to tht dose like it did when you got on that dose when you started taking the methadone. And if that works for u do it until you completely off. Could even try the opposite on the days and instead of taking ur days frm 7 to 9 taking it 7 to 5 or something. It wil work and probably work better than anything. I've also had a friend that was addicted to Xanax and methadone two very lethal drugs when it's mixed!!!!! *I ADVISE EVERyONE TO STAY AWAY FROM THAT COMBINATION it's KILLED MANY MANY people I know in their sleep. *. But this friend went to a suboxen clinic and they made her detox off of methadone before they started her on the subs well they made her start detox nor completely just couldn't take it for like three days I believe. They didn't know her reasons for doing what she was doing bc of course a doctor isn't goin to try and get you off of methadone to turn around and tell you that you don't have to keep taking sub oxen long after your on it. Well she switched to subs and before she let her body get used to it and grab it she allowed the medicine to get her through her methadone withdrawals and out of the clear with that it took her body seven days to soak in the meds good. She took it for three weeks daily and not as much as prescribed either or she may not have been successful possibly. But after taking it for three weeks she quit taking it and because her body wasn't used to the drug like it was the methadone she don't withdrawal and she didn't have any symptoms she was free frm all pills at that point. It was a life saver for sure!!!! I def recommend either of these solutions to anyone that's addicted to methadone. It's an awful drug to shake I know all about it. I'm still battling it today. I know what to do to quit I just haven't made it that far with the decision indefinite. I pray everyday GOD prepares me sooner than later so that I'm not an old lady dependent on anything. I'm 29 and have only been addicted to pills for 4 years which happened in the hospital when I had my first child. Which that happens to a lot of mothers with my type of personality. GOOD LUCK to anyone wanting off of it!!! Anyone can do it with the help of others. There's so many ways to do it too. U learn something new all the time. ;). Hopes this helps and changes a life of an older person that's been addicted their whole lives or a young person that's headed that way. And even for us mothers that love our babies more than life and would love nothing more than to get clean before our babies are old enough to see us self destruct and know the truth. Thank god I still have that chance n hope y'all do too.

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Hello i am on 160 of methadone. I am also 30xr of adderol. I had major hot flashes from the merhadone itself. I finally found a natural cure that works!!!! Bee pollin!!!! U can find bee pollin at a natural foods store. I also take vitadone. My hot flashes have gone away completely as well as severe sweating. Bee pollin helps with many other things including allergies. U just take a tspn of bee pollin. Put under your tongue and chase ghe taste with an orange. :-) hope this helps. It costs about 8 bucks for small bag.

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Wow I'm right there with you I got addicted the same way and I have the same exact concerns about my baby ever being old enough to know what I'm doing to myself. .. Not to mention my husband wants more kids, I won't do that to a baby again next baby I will be clean! No matter what I have to go through its better then the baby having to do it. .. Thank you for all you said it gives me hope and makes me feel a little better to know I'm not the only one going through this that feels horrible about what they are putting their baby's through... Thanks again and I'm sure I'll see you at the clinic...

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Re: Mike (# 84)

You have to know someone's situation before you tell them just to forget the methadone. just for someone to take what you said the wrong way it would be bad and trust me ppl do...it saved me and my sons life and made us stable. i get it though. i been on it for 17yrs.

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Re: Eric Rhoades (# 2)

I'm kind of replying to all. I take 140...Adderall doctor says I can't do that. She said she was scared for my safety of how it would affect me. Kind of like a mixture of a stimulant and a depressant is the way we talked about but not exact. She says she needs to ask my counselor. A lot of people take this. I don't understand why she's taking so long to fix me. Because my dad didn't believe in meds I'm paying for it. My job is also on the line because I keep making the same mistakes. It takes me so long to learn things...its been immortal hell. I took some of my cousins Adderall and it actually had me remember everything the teacher said and understand what was going on? So why would she do this????? Tons of ppl are on a high dose and Adderall.

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Re: lostone (# 16)

You need to come down from the methadone ASAP!! I currently go to a methadone clinic and brought myself up to 126mg every morning, I did more harm than good, I was always tired, drained, I had really bad morning sickness, I would throw up the methadone as soon as I got home and after I threw up I was fine. I was simply overdosing myself. You have to be careful when you increase your dosage at a clinic bc most the ppl there are not qualified and will keep increasing your dose upone your request, know your limits bc they will not. I am currently down from 126mg to 25mg and I tell you what, no more drowsiness or fatigue. The best thing for you to do is to taper Down 5mg a week until you notice withdrawal symptoms then go down to 1mg a week. You are over toxicated and that’s why you feel the way you do. Good luck and hope you gain control of your life.

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Re: Eye (# 40)

Legally theyre not allowed to just cut u off. Thats crazy. A dr is supposed to taper his/her patients off methadone bc it can be Very dangerous to get off cold turkey.

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Re: curtislow (# 14)

Yes This is a DEADLY Combination. Please stop the xanax now. Ive watched/heard of countless friends dying from this concoction. Its not worth it. I have anxiety attacks baaaad.. But I dont EVER take benzos anymore now that Im on methadone. Please dont become a statistic.

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Re: Lollipop (# 8)


I take methadone also. Only 40mgs at the moment. But my advice to you and anyone that's on methadone. Please limit your benzo intake. I've seen and heard of too many of my close friends dying bc of that mixture. Just be careful. Everything in moderation. That's the rule of thumb I like to use and stick by.

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Re: HOT BOSS (# 6)

Clonidine will help with withdraw symptoms. If you are being monitored by a clinic or pcp, they will prescribe the clonidine for withdraw. The medicine helped me in full blown withdraw. So mild withdraw like hot flashes should be helped.

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Re: HOT BOSS (# 6)

I was on 197mg of methadone and I dropped down 2 mg a week for a few months and ended up on 156 mg. As soon as I hit 156 sweat stopped and everything, all that b******* just stopped, it was amazing and I'm almost a licensed massage therapist so I'm consistently working. Massage is a very hard job to do. It's very active and a lot of energy performing the different modalities that people need and the amount of pressure you have to use and so forth and so on. It's the only thing that I can suggest that works for me cuz I had them sweats and nasty nasty sweats up until I started lowering my dosage. The only reason I made it is I was in a bad car accident and I got addicted to prescription pain pills. The truck driver hit black ice and jackknifed the truck and then another one behind him which I was in between the both of them, he hits the same black ice, jackknives and they told me I came through the window from a sign and went through my face right in the center. So my palate which is the roof of your mouth, my teeth and my septum, everything that was in the middle of my face from my nose went down my throat. They fix it. I died three times. I'm lucky to be alive. We tried my to detox and wean myself down from the vicodin because I was just sick of having to buy more because I was so addicted at that point after 3 years I needed more than they could ever give me.

I needed almost double, come to find out my ex-husband was also stealing them but that's another story, but I got to go down really slow. So when they try to detox me I started having seizures really bad so that's why I went on methadone because I didn't want to go on suboxone. I figured god gave me a new life and I was going to take advantage of the new one and not touch any of that bull s*** anymore. So I am still detoxing down. I'm still going and I don't care if it takes me to the next 10 years. I'm going down to 2mg a week unless I start having seizures or seizure-like feelings then I'll stop and we'll know that I'm just going to be a life around methadone that's going to suck cuz it's not anything that anybody would want for themselves but sometimes it doesn't always work out that way. I had a lot of frontal head injuries so it's a ridiculous miracle that they saved my life. I enjoy every minute of life today. Peace and love to all my brothers and sisters who are fighting the drug battle. Keep fighting. It is what it is. We are who we are. I got two degrees now and I own my own business. It can be done, even on methadone. God bless.

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Re: HOT BOSS (# 6)

I have bought vitadone and nutridone last week due to all my hot flashes and sweating because of methadone. I'm on 120 mg of methadone and 40 mg of Adderall. Although I'm not active very much after 6 hours of my methadone. I feel like sleeping all day. So when I told the doctors that, they decrease my methadone and then at about 2 in the morning I started getting restless I couldn't sleep I had chills I was cold I was Restless. Does any of that sound familiar? But anyways I bought the vitadone a nutridone it says it takes like 10 days to help the sweating it's not helping yet but fingers crossed.

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I have been having many problems taking my methadone an adderal. I've had to increase my methadone do to the Adderall burning the methadone up. And now I'm getting tired and the day again because of methadone. I need the Adderall and I need the methadone but this is no life.

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