Bupropion Xl By Cipla Pharmaceuticals (Page 3)

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My pharmacy has been giving me refills of the generic bupropion for my last two refills that are manufactured by CIPLA. The pill is oblong and has the number 13 on one side and what appears to be a capital I on the other side. I do not feel that this generic is doing much for me. I have researched this manufacture they are located in India. Approximately 45% of the medications that are sold in the United States are manufactured in foreign countries. I am going to call my pharmacy to see if they can get one of the generics that were previously dispensed to me. The buyers for drugs at pharmacies look to find lower priced drugs, which I understand.

I have been taking Wellbutrin XL 150 mg three tablets daily for about eight years including the generic form. This medication helped my severe depression. I have tried many other families of antidepressant medications that did not work or caused side effects. The cost for the brand Wellbutrin XL continued to increase because of big Pharma greed (a discussion for another time). Eventually I had to go to the generic Wellbutrin because of the cost and my insurance would not pay for brand or my copay was too much.

When I could no longer work because of my Multiple Sclerosis and another incurable gene mutation condition I eventually received Medicare. I continued to take generic bupropion XL because I had no choice. Various generics of this medication have been dispensed to me for a number of years. The generics have never been a good as the brand Wellbutrin. For those of you that may not be aware a study was done that proved there was a difference between the brand and the generic. The main factor is that generic Wellbutrin XL rises quickly in your bloodstream then drops. The brand Wellbutrin rises up in your blood stream then goes down over a number of hours.

Perhaps for some people the generic form of Wellbutrin works okay for them. In generic medications different fillers are used and the percentage of the main ingredient can be less or higher on either side of the main ingredient. I know a pharmacist that explained this to me that confirmed my suspicions. I take other medications that are generic that seem to do okay. Nevertheless, I firmly believe that certain medications such as antidepressants, seizure medications to include some others should not be propped up as being a bioequivalent.

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41

Re: AnnieMae (# 40) Expand Referenced Message

It's definitely worth investigating. You could also switch pharmacies

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42

Y'all, somehow this kind is really good for me. I take my meds at night, as I can sleep perfectly. However, the past two nights (when I got my refill via Publix) I've been staying up kind of almost all night . But it's more to do with wanting to instead of literally unable to falll asleep.
I will
Seriously hate the never ending switching up super random times. It's ridiculous! Most the time the seitch up has negative effects - SOLCO bupropion 200 SR IS THE WORST SHT EVER. it's actually makers is impossible to pronounce long Chinese name, although the main issue is the TWO different WARNING LETTER S from the FDA about major issues in them faking the testing and using the same exact data and just changing the date ,I mean just all kinds of crazy things . It's available to read if nyone is interested in seeing a very detailed set of warning letters and SOLCO responses (the actual name is like zhuedang zou or something of that nature .

Anyway, I was stuck with the garbage and ended up asking my doctor If he couod prescribe a different form of bupropion so I could get actual medication that worked. I currently take the 300 mg xl . I have not had any issues with these so far.

Just wanted to share !

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43

Re: LOVE (# 10) Expand Referenced Message

How long did you stay on cipla? Because I tried 150 XL and 300 and found myself sinking into what you describe as withdrawals.

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44

Re: BioEquivlaneceMyArse (# 3) Expand Referenced Message

Did your bad side effects from Cipla ever go away? I could swear cipla helped lower my anxiety but messed my cognitive thinking and also eyesight up. Insane issues w processing information and reading

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45

Re: IMGT (# 4) Expand Referenced Message

Did they go away? Does anyone know why we have these side effects.

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46

Re: Eforest (# 28) Expand Referenced Message

How positive are you the Cipla versions of bupropion XL are responsible for withdrawal feelings and awful side effects we all agree with and it isn’t withdrawal from changing generic manufactures ?

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47

I have had problems each time my Buproprion Rx has been filled with Cipla. This last time, it had been years so I had completely forgotten to check which manufacturer the pharmacy had used. Within days I was feeling suicidal and getting ready to blow up my life because of the depression. Then I realized the symptoms started with my new bottle of pills and looked, sure enough it was Cipla. Whatever it is about their version, it severely amplifies my depression instead of resolving it.

I've been taking this prescription for years and have only had issues when using the Cipla generic. All other generics have worked as expected.

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