Bupropion Xl 300 By Lupin (l016) (Page 2) (Top voted first)

Has anyone tried Bupropion XL 300 by Lupin - a round pill marked L016?

Just received these from Walgreen's internet pharmacy and I'm very concerned. I started taking this medication about two years ago, the PAR generic, and everything was great. Then, CVS changed to Cipla and things got bad -- it was only thanks to rxchat that I figured out the problem was caused by the new manufacturer. So, I switched to Walgreens, which had Actavis. It was so much better for me than Cipla but not quite as good as PAR. Quite by accident, I found that when ordering from Walgreen's internet pharmacy I got the med manufactured by PAR.

All's been good for many months... until I just opened my newest prescription and found it's by a newly approved generic by Lupin. Hopefully it will be fine, but I am nervous now.

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Re: Verwon (# 1)

They just switched mine. I was taking the Cipla generic without problems really... picked up my medicine today and I just noticed it looked completely different! How's it going for you? Mine was switched to the lupin version. Makes me nervous since it was just approved this year in April. Anyone have any updated experiences?

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Re: Tina T (# 4)

Tina, I think you're saying that you were switched from one version (likely the PAR) to Cipla? If so, I'm not at all surprised. There are SOO many comments and threads here about the bad reactions people had to the Bupropion XL 300 manufactured by Cipla... so many. Search these forums for Cipla Bupropion and you will see. I myself experienced severe headaches, irritability, depression, high anxiety, etc in the couple months I took the Cipla. The Cipla version is a white oblong pull with I71 on it. If you think you're having a problem with it, start calling to find another pharmacy stocking a different manufacturer. You'll likely notice the difference in less than a week. 0Around here, Harris Teeter currently has the PAR. I think Walgreen's and Rite Aid stores have the Actavis, which I didn't find terrific but still SO much better than the Cipla. Last time I checked, CVS only had Cipla.

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I have been taking Buproprion XL 300 mg for many years for chronic depression. Things had been going fine until last summer when I started having stomach pain and in the evening my legs would develop hives. All would clear by morning and then it would start again. I had a GI workup, almost had my gallbladder out and then after about 3 months it stopped. I have been fine for the last 6 months and the same symptoms restarted. I just realized it was when my Buproprion manufacturer was changed to Lupin with my last refill. I have a severe nickel allergy and wonder if there might be nickel in this generic. Anyone else have these symptoms?

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Re: Peggy (# 21)

thank you for sharing. I'm glad I'm not the only one. It is really messing with me. Do I just ask the pharmacy?

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Re: Avy (# 24)

Thought I was going crazy till I read all these review on the Lupin version of bupropion. Thanks!

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Re: Michelle (# 23)

Yes, tell them to not give you the one manufactured by Lupin.

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Re: mmmm123 (# 13)

I’m wondering, how can the formulations by different manufacturers be so different? Isn’t a generic supposed to closely mimic the formulation of the name brand? Maybe the various manufacturers use lower quality ingredients?

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I'm so glad I found this thread. I've been on Cipla brand 300mg for 4 months. I was feeling great. Got a new Rx filled and the pills were different looking. First day I had a horrible headache. Next couple days I noticed I was very fatigued and my neck and shoulders were so tight and ached. I was falling asleep at 8pm. I'm usually up to 10 or 11pm. Constipated (which never happens). Then I was getting extremely agitated at simple problems encountered at work and at home. I called the pharmacist and explained the switch in manufacturer to Lupin was like I had just stopped taking Bupropion cold turkey. She refilled with Cipla brand and I started to feel better about 6 hrs after taking Cipla again. Thank you all for sharing your experience with the Lupin brand. It's definitely not equivalent to the Cipla brand.

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I have the same problem. Par is the only one that I have found that works for me. I am super discouraged because I just got my prescription from Walgreens and the same thing as you, Lupin. I am going through a break up and I feel very insecure that I don’t have the medication that I know works for me.

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I’ve been having increasing brain zaps and trying to figure out why. I was recently changed over to Lupin. 300. I’m glad to see it could be the issue, though I just got a 90 day supply and have no idea how insurance or the pharmacy will deal. I just dug up some old pills in smaller doses, so I’ll take those tomorrow and see if it helps.

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Re: Bunk Bupropion (# 9)

I agree. There is something wrong with the Lupin version of these pills.

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Trust your gut, is the main message. Lupin causes me dizziness. I’ve been on Bupropion for 10 years and I can tell when I’ve been switched. I’ve never used PAR but Actavis works well for me. It can be hard to get these days. Lupin seems to be everywhere. Let’s all keep complaining to our pharmacist till they stop buying it.

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Re: BJR (# 17)

This thread is about Lupin bupropion, not Cipla or PAR. I'm glad you found a brand that works for you though. PAR seems to have the most positive reviews.

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