Bupropion Xl 300 By Lupin (l016) (Top voted first)

Has anyone tried Bupropion XL 300 by Lupin - a round pill marked L016?

Just received these from Walgreen's internet pharmacy and I'm very concerned. I started taking this medication about two years ago, the PAR generic, and everything was great. Then, CVS changed to Cipla and things got bad -- it was only thanks to rxchat that I figured out the problem was caused by the new manufacturer. So, I switched to Walgreens, which had Actavis. It was so much better for me than Cipla but not quite as good as PAR. Quite by accident, I found that when ordering from Walgreen's internet pharmacy I got the med manufactured by PAR.

All's been good for many months... until I just opened my newest prescription and found it's by a newly approved generic by Lupin. Hopefully it will be fine, but I am nervous now.

REPLY

REPORT

I have been taking bupropion for a few months now. On my last refill, it was changed from a white oblong pill to the Lupin white round pill. I have been taking the Lupin bupropion 300 mg XL (L016 white round pill) for about three weeks now. It has not worked at all. It might be sugar pills as far as I'm concerned. I've had horrible depression and anxiety. I also started smoking again, which is odd, because bupropion is a smoking cessation drug in addition to an anti-depressant, and the other version of bupropion made me quit smoking entirely. I've placed a complaint with the FDA. Lupin is selling placebo pills!

REPLY

Was this helpful? 6

Lupin was terrible. I had been taking cipla for a few months and it was helpful but caused some shakiness and kept me up at night. Lupin was really like I stopped. I began all withdrawal symptoms. Including flu like symptoms which disappeared a couple of hours after I retook cipla.

REPLY

Was this helpful? 3

Re: Bunk Bupropion (# 9)

I took 300 mg Bupropion XL for years (manufacturer Watson). I stopped it in 2015 with no problems whatsoever. In December 2017 I began taking it again for help dealing with an onset of abundance of additional stress, it seemed to be helping (did not check manufacturer). The first refill was a by generic manufactuer I was not familiar with, Lupin. It was like taking a different medication all together. I had not felt that much depression, suicidal thoughts and personality depersonalization in years, I felt so much worse than before I began taking it! I realized it was likely the Bupropion but still did not equate the difference in effectiveness with the manufacturer. I attempted to stop it cold turkey for only 2 horrible, miserable days. Reluctantly I refilled it planning a doctor visit to manage the withdrawal more effectively. After about 2 days I started to feel like myself again and that's when I realized the manufactuer for month 2 was different. My advice from that experience is to check with pharmacist what brand they currently carry (I will every month now!) before getting your refill and avoid Lupin!!

REPLY

Was this helpful? 3

I just started my buporion 150 hcl xl (extended release) from lupin, and I am not happy. I have been feeling very irritable, and my sugar cravings have come back! I'm fine in the morning, but mid to late afternoon, I feel like I can snap at the littlest things. It doesn't feel like extended release to me at all. It's like I get a little "high" in the morning because it's too strong at first, and then in the afternoon I feel like I'm withdrawing or something.

I was taking buporion hcl xl 150 mg(extended release) from global/impax pharmaceuticals, and I felt it was truly extended release. It made me feel the best I've felt in a long time. I'm so disappointed, I'm going to talk to my dr.

REPLY

Was this helpful? 3

How has it been working for you? Does anyone else have experience taking this medication manufactured by Lupin?

The FDA lists its typical side effects as possibly including nausea, dizziness, headache, mood swings, nervousness, and insomnia.

REPLY

Was this helpful? 2

I’ve been taking the Lupin version of Bupropion XL 150mg and then up to 300mg for a couple of months now... right away I had problems with serious constipation. I did buy a probiotic with 50 million micro-organisms and that has seemed to help a little, but not much at all. Other side effects I have noticed are a nasty medicine taste in my mouth in the mornings when I wake up. I usually brush my teeth AFTER coffee but now I have to brush them before to get rid of that taste so my coffee isn’t disgusting and also again after to prevent staining. The energy aspect didn’t last very long for me on the Lupin brand. I do have a few anxiety attacks here and there, but they’re very mild. It seems like the longer I’m on this pill, the worse I feel... I just feel more “blah” each day. I’m also taking this for chronic fatigue as well as depression... so I really need the energy effect. So am switching to the Mylan version tomorrow... hopefully this one will be better for me!! Does anyone have any experience with Mylan?

REPLY

Was this helpful? 2

Re: J (# 6)

I was able to find a non-Cipla version of Bupropion 300mg XL at Costco (CA). I spoke with the pharmacist about the Cipla and he said other folks had issues as well and had transferred prescriptions over. The pharmacist did confirm that the pharmacy may not carry it long due to the cost of the meds vs. the reimbursement from the insurance. Which makes me think that everyone should file complaints so that they can pull Cipla off the market..one day.

REPLY

Was this helpful? 2

Re: Verwon (# 1)

I just found out I was taking Lupin and it did not work. Not feeling well, super anxious and insomnia.

REPLY

Was this helpful? 2

I was taking Global for four months and I was fine. Kroger switched to Lupin and I feel like dog poop. I went to the doc two days ago and he said EOD. The first day I did not take it I felt great. I took one this morning and I feel like I have been hit by a truck. I called and he said just stop. The FDA needs to look into this medication ASAP. Dizzy, nausea, disoriented, faint, terrible.

REPLY

Was this helpful? 2

Re: Michelle (# 20)

Wow- has cut back on PAR generic 150 xl for months, ready to go natural and stressful events made me refill the scrip. For last two months felt spiral downward, experiencing the worst of panic and depression and couldn’t figure out why this was so different- even added CBD to take the edge off. Xmas holidays had to get back to therapy- learned my generic was switched to LUPIN — same as PP, sudden rush then end of day short tempered- also nauseous and anxious all the time. Switched back to PAR, within days back to normal. Seems many probs with Lupin - something is poisonous in their formula.

REPLY

Was this helpful? 2

Re: Verwon (# 1)

I've only been taking this for a week now. I'm not sure what I think. I have been experiencing some dizziness and odd afternoon headaches... but I've also had a cold so I can't yet be certain these things have anything to do with this medication. At this time, I am still very much on the fence about Lupin Buproprion.

REPLY

Was this helpful? 1

I have been taking it for 2 months and it’s given me the most brutal headaches and I’ve become very depressed again. I’m convinced this is a placebo. I’m going back to the one I was on before w the letters a101 on the pills.

REPLY

Was this helpful? 1

Re: Llemo12 (# 5)

I started with 150mg of Actavis and after a week started taking Cipla 300mg XL. After 3 months of taking the Cipla brand everything was great (seriously, i felt a lot better) but 4 days ago i was given the Lupin pill for my refill and literally since the second day I noticed that it wasn't working as well/something wasn't right. I started feeling depressed and anxious again and started getting headaches. So what I did is I went to my pharmacist and told her the new pills weren't working the same for me and she was very nice about it and just exchanged the pills i had left for Cipla ones. Basically, if you get switched and don't feel great about it (even less than a week into it) there's no need to suffer, just ask to go back to the one you were taking! Everyone will have very different/individual reactions to the different manufacturers' pills, but if you have a feeling that it's not the same (in a bad way), don't wait until the next refill! Hope this helps!

REPLY

Was this helpful? 2

Re: Ellen (# 15)

Lupin has a published list of their ingredients. Nickel does not seem to be an ingredient.

Inactive ingredients: ammonium hydroxide, colloidal silicon dioxide, dibutyl sebacate, ethylcellulose, glyceryl behenate, hydrophobic colloidal silica, hydroxypropyl cellulose, iron oxide black, L-cysteine hydrochloride monohydrate, methacrylic acid copolymer dispersion, polyvinyl alcohol, povidone, propylene glycol, shellac and triethyl citrate. The tablets are printed with edible black ink

lupinpharmaceuticals.com/pdf/17/06/bupropion-XL-tabs-mg-10-2016.pdf

REPLY

Was this helpful? 1

Re: mmmm123 (# 13)

At my pharmacy once you walk away no matter what side effects may come they do not return or exchange pills. It has been like this at every longs and cvs I've tried before at so I would say everyone check your prescriptions at the counter! I went through a horrible experience with cipla where I was extremely irritable. Almost psychotic & I just felt like I was losing it which was way worse than the loss of motivation I was taking it for!

Finally got par today and after a couple hours my anger subsided & I felt like a completely different person. So yea idk everyone is different and I'm usually a paradox. On cipla and bupropion in general in the beginning it would knock me out into deep sleep and make me calm and out of it. I feel wide Awake on the par pill. I think cipla is dumping the drug because I had a similar calming effect on addedal before.

REPLY

Was this helpful? 1

Also, I wanted to add I found par at Walmart & when I told them about my reaction and why I was transferring the pharmacist put a note on my file right away to make sure I only got par in the future. So maybe try Walmart if you are looking.

REPLY

Was this helpful? 1

Re: Michelle (# 20)

Have them change the generic to the one made by Pharma. If they don't have it, check other pharmacies.

I've been on Wellbutrin many years. Recently the pharmacy changed to Lupin. All hell broke loose! For 2 months I didn't realize it was the pill. Basically I went cold turkey!

Spread the word!

REPLY

Was this helpful? 2

Re: Peggy (# 21)

Sorry to hear about your experience. Mine was much the same. The reason it feels good in the morning and not in the afternoon is because the XR (extended release) mechanisms are poorly made in Lupin pills.

Ask your pharmacy to switch back to the old generic because Lupin does not work for you. You could also discuss with your doctor switching to bupropion SR twice a day. Switching to SR helped me.

I've also had problems with Lupin quetiapine (Seroquel). I'm almost convinced Lupin is making completely counterfeit drugs. So many pharmacies are switching to Lupin because they're cheap. Placing complaints with the FDA gets absolutely nowhere, because the FDA is full of pharmaceutical executives who are there to purposefully block taking action against pharmaceutical companies.

REPLY

Was this helpful? 1

Update: I've been taking this Bupropion XL 300 by Lupin for slightly over two weeks. I have experienced some mild to moderate afternoon headaches and I just don't feel quite the same as when I was taking the generic manufactured by Par.
The Lupin version, for me, has not been nearly as bad as the Cipla version was. IMO the Lupin version seems comparable, to me, to the Actavis version. That being said, I called around and found Harris Teeter pharmacy fills with Par currently. Therefore, I have once again switched pharmacies.

REPLY

Was this helpful? 0

Re: J (# 3)

I am wondering about your experience with the Lipla brand. I was on a circle pill (maybe the one you are describing, not sure searching my home for the old pill bottles) about a month ago or so they started filling the script with the Lipla brand (oblong pill) and I hadn't thought much of it until I started having bouts of lows and most recently have been unable to pull myself out of the funk or I tend to fall into it far deeper than I have since I've been on meds. I take Biupropion 300xl. Thanks for your feedback.

REPLY

Was this helpful? 0

I haven't found any information on the XL versions of Bupropion by Sandoz. Can anyone share their experience with th...

3 REPLIES

it is ayellow color oblong and it is made by teva i am looking for the ingredients active and non active ## My bupropion...

2 REPLIES

Any reported trouble with the 300XL or 150 XL not digesting? ## Hello, Pat! How are you? This subject has been mentioned...

2 REPLIES

WPI 3332 ## Just to clarify, the pill in description is Bupropion hydrochloride XL (300 mg) To view information about th...

1 REPLY

round off white with WPI 3332 ## It doesn't seem to have the same effect as wellbuterin xl 300. Headaches.... ## And...

3 REPLIES

I've been taking the generic brand PAR of Buproion LX 300MG for over 2 years and haven't run into any problems. ...

33 REPLIES

Hey there, I started taking the dose at night (10 pm)to prevent night sweats and insomnia, which has been working. But I...

1 REPLY

Needing to know if i could take both my meds bupropion xl 300mg and diclofen pot 300mg ## I take Bupropion 300XL, (gener...

2 REPLIES

My pharmacy gave me Bupropion XL 300 mg by Par. I thought I'd managed to take every generic Bupropion out there, but...

2 REPLIES

I’ve been taking bupropion xl 150mg for a couple months now and recently switching to taking 300mg. I had some lef...

1 REPLY