Bupropion Xl 300 By Lupin (l016) (Page 2)
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Has anyone tried Bupropion XL 300 by Lupin - a round pill marked L016?

Just received these from Walgreen's internet pharmacy and I'm very concerned. I started taking this medication about two years ago, the PAR generic, and everything was great. Then, CVS changed to Cipla and things got bad -- it was only thanks to rxchat that I figured out the problem was caused by the new manufacturer. So, I switched to Walgreens, which had Actavis. It was so much better for me than Cipla but not quite as good as PAR. Quite by accident, I found that when ordering from Walgreen's internet pharmacy I got the med manufactured by PAR.

All's been good for many months... until I just opened my newest prescription and found it's by a newly approved generic by Lupin. Hopefully it will be fine, but I am nervous now.

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Re: Llemo12 (# 5)

I started with 150mg of Actavis and after a week started taking Cipla 300mg XL. After 3 months of taking the Cipla brand everything was great (seriously, i felt a lot better) but 4 days ago i was given the Lupin pill for my refill and literally since the second day I noticed that it wasn't working as well/something wasn't right. I started feeling depressed and anxious again and started getting headaches. So what I did is I went to my pharmacist and told her the new pills weren't working the same for me and she was very nice about it and just exchanged the pills i had left for Cipla ones. Basically, if you get switched and don't feel great about it (even less than a week into it) there's no need to suffer, just ask to go back to the one you were taking! Everyone will have very different/individual reactions to the different manufacturers' pills, but if you have a feeling that it's not the same (in a bad way), don't wait until the next refill! Hope this helps!

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I have been taking it for 2 months and it’s given me the most brutal headaches and I’ve become very depressed again. I’m convinced this is a placebo. I’m going back to the one I was on before w the letters a101 on the pills.

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Re: Bunk Bupropion (# 9)

I took 300 mg Bupropion XL for years (manufacturer Watson). I stopped it in 2015 with no problems whatsoever. In December 2017 I began taking it again for help dealing with an onset of abundance of additional stress, it seemed to be helping (did not check manufacturer). The first refill was a by generic manufactuer I was not familiar with, Lupin. It was like taking a different medication all together. I had not felt that much depression, suicidal thoughts and personality depersonalization in years, I felt so much worse than before I began taking it! I realized it was likely the Bupropion but still did not equate the difference in effectiveness with the manufacturer. I attempted to stop it cold turkey for only 2 horrible, miserable days. Reluctantly I refilled it planning a doctor visit to manage the withdrawal more effectively. After about 2 days I started to feel like myself again and that's when I realized the manufactuer for month 2 was different. My advice from that experience is to check with pharmacist what brand they currently carry (I will every month now!) before getting your refill and avoid Lupin!!

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Lupin was terrible. I had been taking cipla for a few months and it was helpful but caused some shakiness and kept me up at night. Lupin was really like I stopped. I began all withdrawal symptoms. Including flu like symptoms which disappeared a couple of hours after I retook cipla.

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I have been taking bupropion for a few months now. On my last refill, it was changed from a white oblong pill to the Lupin white round pill. I have been taking the Lupin bupropion 300 mg XL (L016 white round pill) for about three weeks now. It has not worked at all. It might be sugar pills as far as I'm concerned. I've had horrible depression and anxiety. I also started smoking again, which is odd, because bupropion is a smoking cessation drug in addition to an anti-depressant, and the other version of bupropion made me quit smoking entirely. I've placed a complaint with the FDA. Lupin is selling placebo pills!

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Re: J (# 6)

I was able to find a non-Cipla version of Bupropion 300mg XL at Costco (CA). I spoke with the pharmacist about the Cipla and he said other folks had issues as well and had transferred prescriptions over. The pharmacist did confirm that the pharmacy may not carry it long due to the cost of the meds vs. the reimbursement from the insurance. Which makes me think that everyone should file complaints so that they can pull Cipla off the market..one day.

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I’ve been taking the Lupin version of Bupropion XL 150mg and then up to 300mg for a couple of months now... right away I had problems with serious constipation. I did buy a probiotic with 50 million micro-organisms and that has seemed to help a little, but not much at all. Other side effects I have noticed are a nasty medicine taste in my mouth in the mornings when I wake up. I usually brush my teeth AFTER coffee but now I have to brush them before to get rid of that taste so my coffee isn’t disgusting and also again after to prevent staining. The energy aspect didn’t last very long for me on the Lupin brand. I do have a few anxiety attacks here and there, but they’re very mild. It seems like the longer I’m on this pill, the worse I feel... I just feel more “blah” each day. I’m also taking this for chronic fatigue as well as depression... so I really need the energy effect. So am switching to the Mylan version tomorrow... hopefully this one will be better for me!! Does anyone have any experience with Mylan?

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Re: Tina T (# 4)

Tina, I think you're saying that you were switched from one version (likely the PAR) to Cipla? If so, I'm not at all surprised. There are SOO many comments and threads here about the bad reactions people had to the Bupropion XL 300 manufactured by Cipla... so many. Search these forums for Cipla Bupropion and you will see. I myself experienced severe headaches, irritability, depression, high anxiety, etc in the couple months I took the Cipla. The Cipla version is a white oblong pull with I71 on it. If you think you're having a problem with it, start calling to find another pharmacy stocking a different manufacturer. You'll likely notice the difference in less than a week. 0Around here, Harris Teeter currently has the PAR. I think Walgreen's and Rite Aid stores have the Actavis, which I didn't find terrific but still SO much better than the Cipla. Last time I checked, CVS only had Cipla.

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Re: Verwon (# 1)

They just switched mine. I was taking the Cipla generic without problems really... picked up my medicine today and I just noticed it looked completely different! How's it going for you? Mine was switched to the lupin version. Makes me nervous since it was just approved this year in April. Anyone have any updated experiences?

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Re: J (# 3)

I am wondering about your experience with the Lipla brand. I was on a circle pill (maybe the one you are describing, not sure searching my home for the old pill bottles) about a month ago or so they started filling the script with the Lipla brand (oblong pill) and I hadn't thought much of it until I started having bouts of lows and most recently have been unable to pull myself out of the funk or I tend to fall into it far deeper than I have since I've been on meds. I take Biupropion 300xl. Thanks for your feedback.

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Update: I've been taking this Bupropion XL 300 by Lupin for slightly over two weeks. I have experienced some mild to moderate afternoon headaches and I just don't feel quite the same as when I was taking the generic manufactured by Par.
The Lupin version, for me, has not been nearly as bad as the Cipla version was. IMO the Lupin version seems comparable, to me, to the Actavis version. That being said, I called around and found Harris Teeter pharmacy fills with Par currently. Therefore, I have once again switched pharmacies.

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Re: Verwon (# 1)

I've only been taking this for a week now. I'm not sure what I think. I have been experiencing some dizziness and odd afternoon headaches... but I've also had a cold so I can't yet be certain these things have anything to do with this medication. At this time, I am still very much on the fence about Lupin Buproprion.

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How has it been working for you? Does anyone else have experience taking this medication manufactured by Lupin?

The FDA lists its typical side effects as possibly including nausea, dizziness, headache, mood swings, nervousness, and insomnia.

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