Nucynta Er

Tapentadol

Tapentadol, brand names Nucynta among others, is a centrally acting opioid analgesic of the benzenoid class with a dual mode of action as an agonist of the μ-opioid receptor and as a norepinephrine reuptake inhibitor (NRI).[1] Analgesia occurs within 32 minutes of oral administration, and lasts for 4–6 hours.[3] It is similar to tramadol in its dual mechanism of action; namely, its ability to activate the mu opioid receptor and inhibit the reuptake ...

I am a doctor who treats and "enjoys" a chronic pain problem. My PCP suggested nucynta. We tried it for several months, and I tried it on some of my patients. From my experience in both realms I feel confident in stating that nucynta ER is complete crap! It neither helped me, nor anyone I prescribed it for. I am quite sure that tha pharmaceutical company, however, is pleased with the profits. ## Hello, Tbone! How are you? I'm very sorry about the problem you and your patients had with the Nucynta. It seems to have worked well for some, but to be quite honest, I've read many more complaints about it. Did you report the issues to the FDA? ## Yes, Nuycenta ER is a useless pain medication. I have been using a pain management clinic for over 10 years. I've been on fentany...

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What's Nucynta ER comparable to as far as a pain reliever goes? ## According to the study linked below from NIH.gov, "Tapentadol IR (the active ingredient in Nucynta) has comparable analgesic efficacy and overall safety to that of Oxycodone IR for the relief of moderate to severe, acute lower back pain as well as leg pain" Ref: ncbi.nlm.nih.gov/pubmed/23703422 Another clinical study also compared 50mg and 75 mg dosages of Tapentadol IR to Oxycodone HCl IR 10 mg and reported similar efficacy, at: ncbi.nlm.nih.gov/pubmed/19302899 I understand that this is referring to immediate release and not extended release, but perhaps this information will at least give you an idea of its potency/capabilities and what level of relief you might come to expect. Hope this helps! ## I underst...

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My doctor put me on nucynta er 150 mg x2 daily for chronic pain and I'm not getting any pain relief. Does it take time to work? I've been on it for 3 weeks. ## Hello, Kurtfen! How are you? No, it is an opiate and should have some effect within about 15 to 20 minutes of taking it. However, it could be that it's just not the right medication to help you. The FDA classifies it as a narcotic analgesic, so it has the potential to be habit forming and may cause side effects, such as nausea, dizziness, drowsiness, dry mouth and constipation. Have you informed your doctor of the issue? You may need to try a different medication.

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I have been on morphine er 30 and ir 15 for breath rough pain for 3 years I went to pain management dr today and she switched me to the nucynta 100er, and nucenta 50 for breakthough..does anyone know if this will help my back..I have 3 bulging discs and degenerating disks..I work full time and do alot of lifting and bendin..the morphine had worked great just didn't know if I got use to it. I was reading about nucynta and it says same class as tramadol and that does nothing for me do I need positive feedback that this will work and will I have withdraw from morphine? ## Hello, Renae! How are you? What you have to understand is that all the medications you've mentioned are in the same category, Tramadol is just a very mild opioid in comparison to the others. Nucynta contains the a...

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I take these drugs and I am always sleepy. I also have MS, but I am tired about 3 hours after getting up. Why? Is this a possible side effect? ## It could be due to the medications, since they are all listed as causing drowsiness, dizziness, and sedation as side effects, according to FDA reports. However, according to the NIH symptoms list, it could also be due to your MS. Additionally, it might be a combination of all of the medications, as well as the MS. How are you doing, now? Has there been any change?

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I’ve been using Nucynta ER for several years and doing well with it. My doctor’s office informed me it might become unavailable because of the hurricanes in Puerto Rico, which is where it is manufactured. When I went to refill at the end of January, sure enough, Not Available. How long before it will be available again, and how can I get on a list to be notified of availability? ## In order to find out about current product availability, my thoughts are to get in touch with the manufacturer directly and/or the local pharmacy that generally fills your prescriptions. Do you happen to know who the manufacturer of your previously filled Rx of Nucynta ER is? Most manufacturers have a website with their contact information easily accessible, so this is what I would recommend first...

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I am using Fentanyl 25mg patch for chronic back pain. Is it ok to use nucynta ER 50mg for breakthrough pain? ## Has your doctor prescribed them both? It is unusual to prescribe 2 time released medications, together. That's not usually the way breakthrough pain is handled, usually there is one time released medication and one instant release, or regular release medication, because they help with pain much faster than a time released medication.

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I was having issue finding my Dilaudid Rx. I ran out and the pain was unbearable. (I used my Rx for Tramadol 50mg x 4-6 daily to alleviate any withdrawals. It doesn't do much for the pain.) My doc switched me to a new time released med Nucynta ER or Tapentadol. It works great. It comes in 50mg - 250mg. Equivalent for my Dilaudid 4mg x 4 was Nucynta ER 150 mg, 1 q 12 hr. but we had to work up to that dosage through titration. It says not to cut the pill and I have not tried. If you have true pain and a legal doc, try this. It is readily available at CVS, usually the 24 hour stores. I don't wake up in knots and crying in pain. I am very relieved not to have to drive to 15 different drug stores and be looked upon as a junkie/criminal to get my meds. This works for now and I'm n...

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What are the best times to take Nucynta ER? I take it in the morning but it wears off in the afternoon and I don't feel well. ## There are really no best times to take it, it depends on what works for you. If it's wearing off fast, you may need a dosage adjustment, or you might need to try a different medication. The FDA warns that Nucynta carries the risk of being habit forming and may cause side effects, such as nausea, dizziness, headache, constipation, and dry mouth. Is this the only medication you are currently taking? ## Nucynta is a time released pill so this is why it doesn't work well. nowadays with the war on opiates chances are you won't be giving a narcotic that works well for pain it's very sad for people like me who suffer daily with chronic pain thanks...

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I've been on the OxyContin 40mg 1 tab 3x day for about 15 yrs. 3 years ago my insurance took it off their Formulary list. 1st Year my doctor got the insurance to approve it. Last year I was put on the Opana which made me sick, throwing up every time I took it. The insurance approved me again to the OxyContin. This year it was denied so I am on the Nucynta ER 200mg 2x's a day. I have had 2 Cervical Fusions leaving me with a plate & 15 screws in my neck. I've had a Reverse Right Shoulder Replacement. I have also had 14 Lumbar Surgeries. I know they put a cage in & fusions. The last surgery the doctor cut my whole back open. I have been back to his office 1 time after falling 2 days after coming home. I saw his PA not the doctor who did this surgery. I've not been b...

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Hi there, New to this forum, and appreciate any replies/feedback. My PM doc (who has changed my meds each visit x3) Rx'ed Nucynta 50mg 3x day, a change from Percocet 10/325mg 3x day for BTP. Also switched to Oxycontin 10mg every 12 hours (from Opana ER) Stated he wished to "lighten any burden on my lungs" given my medical status: pulmonary nodules which are increasing in size, both lungs, biopsy next month; severe asthma, residual COPD S/P bilateral PE's 10 years ago. Using Symbicort inhaler. I am uncertain how Nucynta would lighten the burden on my lungs, given the warning about lung conditions/impairment, and specifically asthma--of course, respiratory depression can occur with many pain meds. I also have hypothyroidism & seizures, which are both listed in precauti...

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I've been on 75mcg fentanyl patches for about a year. I started having some issues with my blood sugar and sweating that I thought were from the patch. Then this month I found out my wife had been using them so I spoke to my doctor about changing. On 3/4 he switched me to 50mg nucynta er twice per day. Told me to discontinue the patches immediately. I did and had the left overs destroyed or whatever they do with them. I was fine for about a day and a half. Then started feeling very anxious and nervous. I would note the first night I did have hives on my arm but they went away quickly and I associated them with someone's body spray. Now it's been 5 days and I haven slept in 3. I have hydrocodone but I'm only supposed to take no more than 4 per day but my doctor hasaid tol...

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My sister was taking Nucynta and Prednisone for her Rheumatoid Arthritis and it weakened her immune system. She had only been taking these 2 medications about a year. One day she got strep and it killed her. Within a couple of days of feeling sick, she was rushed the ER and passed away. She died of septic shock. I blame the drugs. ## Hello, Diana! How are you doing? I am so very sorry for your loss. Prednisone is a steroid class medication that can cause suppression of the immune system, so yes, it could have contributed to the problem. It can also headache, fluid retention and weight gain. However, not being a doctor, I can't say with certainty that it did. Have they attributed her death to anything? What do they say was the cause?

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I have been on this new EXPENSIVE drug EXALGO 16mg, The doctor's around here do not want to prescribe what I can take ( I am allergic to so much) and this stuff makes me sick and I break out in Hives worse then any other medication I have been on! Not only did my insurance have to make a fuss over covering this $750.00 medication for 30 a month but now that they are it is not helping me as well as my Nucynta's did and he wont put me back on them or NO DOCTOR in my area will give me the Rodxycodone due to the addicts, I don't want to be on a Schedule 2 drug but they claim I am seeking if I want something no as strong. What is wrong with these physicians these days, the ones that are not addcits can't get squat but send a addcit into the office and they come out with 2 or ...

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My sister was taking Prednisone and Nucynta for her Rheumatoid Arthritis and it weakened her immune system. She had only been taking these 2 medications about a year. One day she got strep and it killed her. Within a couple of days of feeling sick, she was rushed the ER and passed away. She died of septic shock. I blame the drugs. ## Hello, Diana! How are you? I am so very sorry for your loss. Steroid class medications, such as Prednisone, can cause suppression of the immune system, along with other side effects, such as weight gain, acne, dizziness and fluid retention. So, there is a chance that it might have contributed, but I'm not a doctor, so I can't say with certainty. How are you taking it? Are you okay? ## Hi, yes thank you. I'm ok. This was two, almost three years a...

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I suffer from chronic pain/neuropathy. I am medically disabled due to the neuropathy and chronic pain. Currently I am taking A total of 400 mg of Nucynta ER daily and a total of 200 mg of the center I are daily. Initially I was taking 200 mg ER in the morning 200 mg at night and 50 mg of IR in the morning and 50 at night. However, after several months, I found out that my pain was more controlled by taking 400 mg of your center in the morning and 100 mg of BIR in the morning also for total of 500 mg this work much better for me and my pain generally was controlled from 8 to 12 hours depending on activity and other issues The problem is that after about 6 PM every evening I am in severe pain again with no medications left . After checking the physicians desk reference PDR, I found out th...

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about the size of pencil era. .flat,round,sorta squre edges. one side 75,the other o-m. ## This is a 75mg Nucynta tablet, that contains the active ingredient Tapentadol, which is a narcotic analgesic. Side effects may include: nausea, headache, dizziness and constipation. Learn more: Is there anything else I can help with?

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Hi, all, I just moved to Covington, KY from. Brooklyn, NY. I am taking Nucynta ER 150 mg/3 x a day, lyrica, celexa, Xanax 2 mg/3 x a day and a muscle relaxant. The main issues are the Nucynta and Xanax. I have had doctor after doctor laugh in my face when asking for this prescription. I started Xanax five years ago and Nucynta about a year ago. No one wants to prescribe Nucynta, either. I have tried Vicodin, oxy--everything. But finally found that Nucynta (a drug I paid $1500 for WITH insurance in NY) works for me. (I am a full time children's book author who spends 12 hours a day on the computer.) I am not an addict and will willingly comply to all drug panels. Can anyone recommend a psychiatrist in or near Cincinnati as well as a pain management doctor or clinic? Thank you, all, i...

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I have severe joint pain throughout my body. It has been extremely severe these past few months. Unable to drive on bad days. Barely able to walk. Milder attacks allow me to drive and walk w/ a cane due to herniated and broken lower disks. My PM doc has put me on 200mg Nucynta ER 2x daily and 100 mg Nucynta for break through pain. Most recently they put me on 30mg Morphine ER which did not seem any better than Nucynta. Does anyone have any idea why every joint in my body would become so painful as to immobilize me? On bad attacks the Nucynta 200mg ER, 100mg for break through pain and 150mg Lyrica barely make a dent in the pain. Besides weight gain, I now have diabetes as I have been taking Nucynta, Lyrica for over 6 years but the 200mg ER was recently added and I was removed from the Nu...

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