Autonomic System

I have been on Flecainide for 15 years. I have read that there have been studies saying that it can cause peripheral neuorpathy, but does does anyone know if it can cause the more insidious infiltration into the autonomic nervous system (ex- nerves that communicate with the heart thus causing cardiovagal failure or nerves that communicate with the bladder causing urinary inconinence...)? I just got back from Mayo Clinic where my sweat test and autonomic tilt table test were severely abnormal. The doctor said that it is not just sudomotor failure/peripheral neuropathy, but that the nerves that communicate with the organs are also damaged. I also have developed orthostatic hypotension so that I seem dizzy all the time and especially when I change positions. The ringing in my ears is so ba...

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As soon as I was put on Bisoprolol, I complained of breathlessness and feeling as if my lungs no longer worked automatically. I complained that I felt like a drunk zombie, that Bisoprolol had turned me into an old man overnight. Thing is, I stopped taking any beta blockers eight months ago, but all the symptoms that started from the day I took Bisoprolol remain to this day, I an so exhausted that I can only get out of bed every other day, my lung oxygen content has gone down to 85% when asleep, my heart rate is variable for no reason. But nobody in the medical profession will acknowledge that Beta Blockers have residual side effects and so say I have anxiety, which I certainly am unaware of. In view of the fact that Beta Blockers effect receptors of the Autonomic Nervous System, and all...

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Drug Category

Migraine is a chronic neurological disorder characterized by recurrent moderate to severe headaches often in association with a number of autonomic nervous system symptoms. The word derives from the Greek μικρανα (hemikrania), "pain on one side of the head",[1] from μι- (hemi-), "half", and κρανον (kranion), "skull".[2] Typically the headache is unilateral (affecting one half of the head) and pulsating in nature, lasti...

Caffeine

Caffeine is a central nervous system (CNS) stimulant of the methylxanthine class.[11] There are several known mechanisms of action to explain the effects of caffeine. The most prominent is that it reversibly blocks the action of adenosine on its receptors and consequently prevents the onset of drowsiness induced by adenosine. Caffeine also stimulates certain portions of the autonomic nervous system. It is also used as a cognitive enhancer which increases alertness and attenti...

Caffeine

Caffeine is a central nervous system (CNS) stimulant of the methylxanthine class.[11] There are several known mechanisms of action to explain the effects of caffeine. The most prominent is that it reversibly blocks the action of adenosine on its receptors and consequently prevents the onset of drowsiness induced by adenosine. Caffeine also stimulates certain portions of the autonomic nervous system. It is also used as a cognitive enhancer which increases alertness and attenti...

Caffeine

Caffeine is a central nervous system (CNS) stimulant of the methylxanthine class.[11] There are several known mechanisms of action to explain the effects of caffeine. The most prominent is that it reversibly blocks the action of adenosine on its receptors and consequently prevents the onset of drowsiness induced by adenosine. Caffeine also stimulates certain portions of the autonomic nervous system. It is also used as a cognitive enhancer which increases alertness and attenti...

Drug Index

Caffeine is a central nervous system (CNS) stimulant of the methylxanthine class.[11] There are several known mechanisms of action to explain the effects of caffeine. The most prominent is that it reversibly blocks the action of adenosine on its receptors and consequently prevents the onset of drowsiness induced by adenosine. Caffeine also stimulates certain portions of the autonomic nervous system. It is also used as a cognitive enhancer which increases alertness and attenti...

Caffeine

Caffeine is a central nervous system (CNS) stimulant of the methylxanthine class.[11] There are several known mechanisms of action to explain the effects of caffeine. The most prominent is that it reversibly blocks the action of adenosine on its receptors and consequently prevents the onset of drowsiness induced by adenosine. Caffeine also stimulates certain portions of the autonomic nervous system. It is also used as a cognitive enhancer which increases alertness and attenti...

Caffeine

Caffeine is a central nervous system (CNS) stimulant of the methylxanthine class.[11] There are several known mechanisms of action to explain the effects of caffeine. The most prominent is that it reversibly blocks the action of adenosine on its receptors and consequently prevents the onset of drowsiness induced by adenosine. Caffeine also stimulates certain portions of the autonomic nervous system. It is also used as a cognitive enhancer which increases alertness and attenti...

Caffeine

Caffeine is a central nervous system (CNS) stimulant of the methylxanthine class.[11] There are several known mechanisms of action to explain the effects of caffeine. The most prominent is that it reversibly blocks the action of adenosine on its receptors and consequently prevents the onset of drowsiness induced by adenosine. Caffeine also stimulates certain portions of the autonomic nervous system. It is also used as a cognitive enhancer which increases alertness and attenti...

Hi I am wondering if others who are on the maximum dosage of 40mg still experience on-going depression for a few hours afterwards. I take my meds in the morning but it takes several hours for me to feel ok. I have small fibre neuropathy of the autonomic nervous system and have been on citalopram for 3 1/2 years. Recently I ave put on weight. I haven't always felt this on-going depression. It seems to be getting worse. Has anyone had ths experience when after a reasonable time on the drug it seems not to be working as effectively? ## Hi Chris, The reason why the medication seems to be not working as effectively over time, is generally due to the tolerance or physical addiction of the drug itself. As for Citalopram, it's not addictive, but you can build up a physical tolerance - m...

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Drug Index

Acetylcholinesterase inhibitors (AChEIs) also often called cholinesterase inhibitors,[1] inhibit the enzyme acetylcholinesterase from breaking down the neurotransmitter acetylcholine into choline and acetate,[2] thereby increasing both the level and duration of action of acetylcholine in the central nervous system, autonomic ganglia and neuromuscular junctions, which are rich in acetylcholine receptors.[2] Acetylcholinesterase inhibitors are one...

Inotersen Sodium

Polyneuropathy (poly- + neuro- + -pathy) is damage or disease affecting peripheral nerves (peripheral neuropathy) in roughly the same areas on both sides of the body, featuring weakness, numbness, and burning pain.[1] It usually begins in the hands and feet and may progress to the arms and legs and sometimes to other parts of the body where it may affect the autonomic nervous system. It may be acute or chronic. A number of different disorders may cause polyneuropathy, includin...

Drug Index

Polyneuropathy (poly- + neuro- + -pathy) is damage or disease affecting peripheral nerves (peripheral neuropathy) in roughly the same areas on both sides of the body, featuring weakness, numbness, and burning pain.[1] It usually begins in the hands and feet and may progress to the arms and legs and sometimes to other parts of the body where it may affect the autonomic nervous system. It may be acute or chronic. A number of different disorders may cause polyneuropathy, includin...