Vidarabine

Vidarabine or 9-β-D-arabinofuranosyladenine (ara-A) is an antiviral drug which is active against herpes simplex and varicella zoster viruses. Contents 1 Discovery 2 Mode of action 3 Mode of resistance 4 Synthesis, preparation and isolation 5 Selectivity 6 Clinical indication 7 References Discovery In the 1950s two nucleosides were isolated from the Caribbean sponge Tethya crypta: spongothymidine and spongouridine; which contained D-arabinose rather than D-ribose. These compounds l... [wikipedia]