Active Ingredient(s): Tocainide
FDA Approved: * November 9, 1984
Pharm Company: * ASTRAZENECA
Category: Irregular Heartbeat (Arrhythmia)

Tocainide (Tonocard) is a class Ib antiarrhythmic agent. It is no longer sold in the United States. Contents 1 Pharmacokinetics 2 Synthesis 3 References 4 Further reading 5 External links Pharmacokinetics Tocainide is a lidocaine analog, that does not have significant 1st pass metabolism. It is found in two enantiomers. The R isomer is 4x as potent as the S. Oral bioavailability is 0.9-1.0. In the blood tocainide is 10-20% protein bound. The Volume of distribution is 2.5-3.5 L/kg. ... [wikipedia]

* May have multiple approval dates, manufacturers, or labelers.