Mibefradil
Category: Blood PressureMibefradil (Posicor) was a drug used for the treatment of hypertension and chronic angina pectoris. It is a nonselective calcium channel blocker. It was voluntary pulled from the market 10 months after FDA approval, citing potential serious health hazards shown in post release studies. [1] The mechanism of action of mibefradil is characterized by the selective blockade of transient, low-voltage-activated (T-type) calcium channels over long-lasting, high-voltage-activated (L-t... [wikipedia]