Lumasiran
Category: Genetic DisordersLumasiran, sold under the brand name Oxlumo, is a medication for the treatment of primary hyperoxaluria type 1 (PH1).[4][2][5] The most common side effects include injection site reactions and abdominal pain.[2] Lumasiran is a double-stranded small interfering ribonucleic acid (siRNA) that reduces levels of glycolate oxidase (GO) enzyme by targeting the HAO1 messenger ribonucleic acid (mRNA) in hepatocytes through RNA interferenc... [wikipedia]