Active Ingredient(s): Dirithromycin
FDA Approved: * June 19, 1995
Pharm Company: * LILLY RES LABS
Category: Antibiotics

Dirithromycin is a macrolide glycopeptide antibiotic.[1] Dirithromycin (Dynabac) is a more lipid-soluble prodrug derivative of 9S-erythromycyclamine prepared by condensation of the latter with 2-(2-methoxyethoxy)acetaldehyde. The 9N, 11O-oxazine ring thus formed is a hemi-aminal that is unstable under both acidic and alkaline aqueous conditions and undergoes spontaneous hydrolysis to form erythromycyclamine. Erythromycyclamine is a semisynthetic derivative of erythromycin in w... [wikipedia]

* May have multiple approval dates, manufacturers, or labelers.