What Is Zertin Capsule?
Updatedcapsule..with green and yellow colored capsule 300mg
6 Replies
Erdosteine.
Dechant KL, Noble S.
Adis International Limited, Auckland, New Zealand.
Erdosteine is a thiol derivative developed for the treatment of chronic obstructive bronchitis, including acute infective exacerbation of chronic bronchitis. Erdosteine contains 2 blocked sulfhydryl groups which are released following first-pass metabolism. The 3 active metabolites exhibit mucolytic and free radical scavenging activity. Erdosteine modulates mucus production and viscosity and increases mucociliary transport, thereby improving expectoration. It also exhibits inhibitory activity against the effects of free radicals produced by cigarette smoke. Clinical studies in patients with chronic obstructive lung disease have demonstrated the efficacy and tolerability of erdosteine. Erdosteine 300mg twice daily reduced cough (both frequency and severity) and sputum viscosity more quickly and more effectively than placebo and reduced the adhesivity of sputum more effectively than ambroxol 30mg twice daily. Co-administration of erdosteine and amoxicillin in patients with acute infective exacerbation of chronic bronchitis resulted in higher concentrations of the antibiotic in the sputum, leading to earlier and more pronounced amelioration of clinical symptoms compared with placebo. Erdosteine is associated with a low incidence of adverse events, most of which are gastrointestinal and generally mild.
Publication Types:
* Review
PMID: 8957158 [PubMed - indexed for MEDLINE]
GENERIC NAME OF ZERTIN
I used to take zertin for 7 days at two times a day in conjuction with a powerful antibiotic for my excessive phlegm and coughing.
The symptoms disappeared after the 7 days medication but the phlegm remained in my throat for several days more. Anyone can tell me what to do with phlegm in my throat?
Shaira I think you need to take Aleva for your medication requirement
My doctor gave me augmentin 625mgs. 2x day coz i developed fever due to my coughing...d phlegm is infected coz its color is greenish... She prescribed zertin, too, once a day only. I have sticky phlegm...she touched my neck, she said there was lymp nodes. True coz i can feel li'l discomfort in my mouth. Let's see what will happen,,,this is only d first day
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