Topamax And Muscle Spasms In Left Knee (Top voted first)

I was put on Wellbutrin 150 XL..and for awhile did really well on that. Then started feeling somewhat depressed again and she increased it to 300 XL once a day. That's when I noticed muscle tics in my lower legs right before I went to sleep or upon waking up. Then started having twitches in stomach, buttocks, then under lips, inside cheeks, then under left eye. I went to my pharmacist and he said he hears alot of complaints about Topamax which I have been on for 8 months. 25mg in morning..50 mg at night. Talked to Psychiatrist who said I do not need to worry about Arrive Dyskensia..and she kept me on Topamax and put me on Wellbutrin SR 200 once a day..and told me to get my electrolyte levels checked. Went to Doctor, he said they did blood work 4 months ago, and I was not deficient in anything. He said maybe get Magnesium Oxide over the counter..which is not helping, nor Potassium supplements..or prescribed Muscle relaxers. Now about 2 days ago, the under eye twitching went away, but I m having rapid jerking constant muscle non-stop muscle spasms by my left knee cap..all day and all night. I'm at my wits end. No one will help me, and I don't know what to do. Will probably go to ER..is anyone else having this?

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It is March 8th..taking Potassium supplements now. Went to a Family Doctor who said that when my blood was drawn 4 months ago..I was not deficient in anything. Then he got cocky and said "it just means you are alive" and started laughing. He is getting ready to retire soon and I am glad, as I don't feel he has my best interests at heart. My left knee is still twitching. I'm very worried. I guess I will call Neurologists, but I probably need a referral. Definitely going to look for a new Doctor. If anyone is having a similar issue, please reply. I really don't want to have to go off Topamax.

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Muscle spasms can be a side effect of Topamax, and Wellbutrin, but they are more commonly experienced from Topamax, according to FDA reports, occurring in anywhere from 1% to 10% of people that take it. Other side effects may include nausea, dizziness, anorexia, and blurred vision.

Ref: Topamax Information

Ref: Wellbutrin Information

Since they both can cause it, it might even be that the combination is too much for your body.

As to your doctor, he should know that blood work from 4 months ago may not be relevant, now, things can change fast, when there is a medical issue, and he should have checked, again, anyway. Have you considered trying a different doctor?

Are you on any other medications?

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