Oxycontin Doesn T Work
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Hi, I've been on 30mg of oxycodone a day_-20 mg on waking and 2 sep. doses 5 mg through day. I have a severe neuropathic/nerve pain and an upregulated central nervous system which includes akathisia. The oxycodone had been a life saver. It also stopped the terrible depression and terror I had been feeling since a bad medication reaction brought on this whole syndrome. One more 5 mg a day would have been really needed, but at least I had started to feel I could survive and life was starting to improve. I was really staring to enjoy living again much of the time. Long story, govt. steps in, no more oxycodone. Saw lovely pain specialist, and he's put me on oxycontin 30 mg morning, 15 mg night. This was 6 days ago. Each time I've taken oxycontin, instead of the unagitating, untwisting of my nervous system, it has made it worse, neuro pain in legs, restlessness,agitation, depression and yesterday severe tension in CNS and vomiting bile. Depression has deepened and feeling terror today which I had forgotten about. He gave me a pack of oxycodone for emergencies, and over Easter I used it a number of times to survive the oxycontin side effects. How can this be when both drugs are the same? I know the fillers are different, but I'm scared and bewildered. Thanks for listening.

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HEY THERE.. It sounds like the doc really tried to match the meds near equal when he changed them. Your old dose of 20mg immediate release was substituted with 30 mg of the extend. Release (which sounds correct since he raised it a little to offset the difference between I.R. and E.R..) and then your old 10mg of I.M. was substituted with the higher dose of the extended release for the balance of your day and throughout the night. So this really is the proper way to substitute these. However was this negative reaction of the change that you experienced an on going problem? Or did you try and give it a week or 2 for your system to adjust? It really sounds odd that it's not working well..I speak from years of experimenting myself due to 4 failed spine surgeries over a span of 20 years.. It's sad that this is now happening to you. So im trying to understand if you were forced to change to the oxycontin E.R.? I have found even the generic oxycontin is 3x more expensive than oxycodone I.M. in same mg, and that is just plain stupid. I also know that i share your feelings as far as the oxycontin E.R not working as well as oxycodne I.M. even when my dose was adjusted up slightly. However I did not experience those other bad side effects that you were talking about. If you and your doctor are willing to experiment and try some different medications to try and match the same quality of pain relief that the oxycodone immediate-release was giving you. FYI..There are different meds out there you could try, like Opana and morphine just to name a few. I know it's a timely brutal process and aggravating to experiment but it could be worth it. One more thing I wanted to add, have you tried adding a antidepressant to your daily medication intake? A antidepressant that enhances and stimulates both parts of the brain and not just one part. An example of a anti depressant medication that stimulates both is called Effexor, and an example of an antidepressant medication that only stimulates one part of the brain is Prozac. I found the Effexor works wonders however it can be difficult coming off of it if you ever choose to do so.. Both of these meds and most antidepressants are considered to be safe in conjunction with these narcotic pain medications, but please check with the doc or pharmacist.. I feel your pain and I understand your pain. You're not alone in this battle! I wish you all the best.. If you would like to respond for any reason feel free to do so. {edited for privacy}

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Well, the Oxycontin is time released, so you're not getting the same immediate bolus that you were, when you were taking the regular release formulation.

The regular release is all released and working about 15 to 20 minutes, after you take it. The time released Oxycontin, however, releases small amounts of it, very slowly, over a period of 12 hours. So, it is natural that the effects would be different, even though the active ingredient is the same.

The FDA classifies this medication as a narcotic analgesic, so it has the potential to be habit forming and may cause side effects, such as nausea, dizziness, drowsiness, dry mouth and constipation.

Is it possible that he can still prescribe a small dose of the regular release to help you?

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