Opana 40mg Vs Oxycontin Op 80mg (Page 2) (Top voted first)

my Dr prescribed Opana 40mg as alternative to Oxy 80 mg 2 twice a day which I would insufflate - I didn't tell him this of course. he claimed them to be just as good if not stronger can any one share about opana 40mg

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I'd like to start by saying that i am honestly astonished at how many of you either have NO idea what drugs you are taking, whats in them, how they work ect, or are just grossly misinformed by other on this forum. First of id like to just clear up basic misunderstanding and ignorance of basic opiate painkiller.
Natural Opiates= Codeine, Morphine; these are drugs that are found in small percentages naturally in the opium poppy.
Morphine comes in many different forms. MS Contin is Morphine Sulfate Contin, the contin simply means that it is a sustained release medication that will release the medication slowly throughout the day. Other forms are just plain morphine that is released immediately. Names like Kadian, and Avenzia are just the names of pharm companies and different fomulations of the same morphine.
Hydrocodone: Vicodin, Vicoprofen, Norco. is roughly 1/2 the strength of oral morphine with 17mg being equivalent to 10mg oral morphine.
This is the most commonly prescribed narcotic painkiller. Comes in a variety of combinations with Tylenol (paracetamol) and Ibuprofen, from 5mg/325mg-7.5/750mg. When the dosage of actual hydrocodone is 10mg the pills are called Norcos instead of Vicodin.

Hydromorphone: Dilaudid, Palladone, ect. Semi-Synthetic opiate, roughly 5x the potency of Morphine, with 2mg being equivalent to 10mg of oral morphine. Although its potency if markedly stronger than morphine it has the draw back of very poor bioavailability when taken orally, about 30-35%. This improves with other routes of administration, intranasal administration (snorting) improves bioavailability to about 45-60%. If anyone has ever had the pleasure of IV hydromorphone in the hospital (or otherwise) will know that this by far the BEST route of administration, the rush is so intense some find it uncomfortable, very novel opiate. The 1,2,4, and 8mg IR pills are novel among opiate painkillers in that they contain the least amount of binder/filler in proportion to the actual amount of Hydromorphone making them well suited for illicit injection.

Oxycodone: Oxycontin, Roxicet, Roxicontin, Percocet, Percodan. Synthetic Opiate roughly 1.5-2x the potency of morphine with 5-6.5mg being equivalent to 10mg of oral morphine. Comes in a variety of formulations, when combined with aspirin it is called Percodan, when combined with Tylenol it is called Percocet. It also comes in the Instant Release formula containing only Oxycodone and as the Contin formula which is SUPPOSED to provide 12 hour pain relief. Oxycodone has one of the best bioavailabilities when taken orally with upwards of 87% of it available orally. Whether or not the new OP's work for you is an individual thing, some will find no difference in the new formulation while others can not or more likely WILL NOT tolerate it for a variety of reasons.

Oxymorphone: Opana; Synthetic opiate. *NOT A COMBINATION of OXYCONTIN AND MORPHINE* just because the name sounds like that does not mean thats hows its made, anyone who said or believes that is just plain ignorant and poorly informed. Roughly 7x the potency of morphine with just 1.4mg being equivalent to 10mg oral morphine. However while it may being exceptionally potent it has one of the lowest bioavailabilities amongst opiates, just 10-30% is absorbed when taken orally, which answers some of your question as to why people want to snort, inject or rectally administer this medication. Snorting increases both how much of the medicine and how quickly is absorbed into the bloodstream, while more dangerous it does offer the full spectrum of benefits offered by this medicine. The ER formulation of Opana contains what is known as the TIMERx system, which is the mechanism that traps the oxymorphone within the binder/filler making it nearly impossible to inject. Little known fact was kind of the OxyContin of the 70's amongst pill junkies; they were called blues and were highly sought after because of how easily they were crushed, dissolved and injected, much in the way that can/is done with Diluadid pills.

Fentanyl: Sublimaze, Actiq, Duragesic; Synthetic opiate roughly 50-100x the potency of morphine with just .1mg-.2mg being equivalent to 10mg morphine. Fentanyl is an ultra-short acting opiate lasting on average 1.5-2hrs, which is why it is most commonly delivered transdermally (via contact with skin) over the period of 2-3 days with a continuously worn patch as oral doses would be very small and require constant re-dosing. Many find that the slow absorption thru the skin doesnt allow them to fully feel the effects of this medicine while others find it overpowering by the 2nd day and take it off prematurely. And when referring to Fentanyl it is important to note that you are talking MICROgrams and not Milligrams. A 75mcgrm patch for instance has 7.5mg that is released over the period of 72 hours. Roughly 100micrograms per hour.

*Important Reminders*
Its important to remember that while Opana (oxymorphone) is well over 2x the potency of OxyContin(oxycodone) their bioavailabilties vary greatly. While with Oxycodone you can expect to get about 90% of the medicine with oral administration, when taking Opana remember that only 10-30% will be absorbed when taken orally. This means that if you take 80mgs 2x daily for 160mg, you will have gotten upwards of 144mg of the drug.
On the other hand if your taking 40mg Opana 2x daily for a total of 80mg and you got at best 30% oral bioavailability you will realistically only have gotten about 24-25mg of the drug. And since opana is a little over 2x the potency of oxycontin you will have ingested roughly less than half the painkilling ability of the OxyContin.

This is a helpful chart when you and your doctor are considering changing medication, so you stay properly medicated.

I really hope this helped some and help to clear up some confusion. I openly welcome anyone to challenge my details and findings and i will be more than willing to make adjustments to my info as needed, but i put this up in response to some blatantly misinformed people so i hope you reconsider your assumptions (oxymorphone being morphine and oxycodone) and try to lend better advice in the future.


*Added note*
This has nothing to do with drugs, but Christianity DOES NOT comprise 80% of the worlds religion, as someone else previously showed you with a source, Christians comprise roughly 2.2 billion or just a little under 1/3 of the worlds population. So your information is grossly inaccurate.

PLEASE PEOPLE LETS STRIVE FOR ACCURATE INFORMATION! KNOWLEDGE is POWER!

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I totally agree with what you said. My entire back is nearly plated, and my hip is due to be replaced in 3 weeks. My pain management center stopped prescribing my OxyContin due to fear from FDA citations from ppl snorting it and abusing it, Ppl with sever chronic pain are made to suffer from stupid addicts and test are done one people with little or no tolerance. One of the main concerns I agree with is nothing lasts 12 hrs. 6 at most. ER's tend to spike up and down and you have no control over when. (So for example... Taking a walk with your grandchild . Then BOOM. SEVERE PAIN. 30 minutes later. You can resume. )

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Yes my suggestion to you is stop abusing the drugs that ppl like me and a lot of other ppl actually need just to get through the day. If you want to be a junkie just go get H and blast it in your arm and I hope its bad cause its ppl like you that ruin it for ppl like me that actually need the meds and take them as prescribed. P.S. I hope to god you get caught thrown out of clinic you go to and or get caught misusing them and do not pass go,do not collect another script ever again and go directly to jail and have to detoxify cold turkey. Maybe that will open you're eyes so you can see the err of you're ways and see how you and ppl like you have ruined what little relief I did use to get but don't any more because of the anti abuse agents they are putting in everything now nullify the pain relief of the originals. Thanks a lot loser junkie.

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I HAVE BEEN ON OCY 80 FOR TWO YEARS AND THE NEW ON MAKE ME ITCH SHOULD I TELL HIM THAT SHOULD I ASK FOR OPANA 40

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Bohica, I find that standard hydromorphone (Dilaudid) works great. It is pretty cheap and quick acting. Maybe try MS Contin (morphine sulfate ER) and the hydromorphone. I hated the patches and suckers (fentanyl), got sleepy and pain relief was not very good plus ruined my teeth. Might also try increasing the OP's. They still work for me, but are about 20-30% less effective. Most people want to abuse them and are really pissed. I hope your doc. works with you, if not change. I know that is easier said than done. I pray you find stable relief.

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This is not a forum for Narcotics Anonymous, so please stop preaching about what you SHOULD do and SHOULDN'T DO!

The new Oxycontin is DEFINITELY less bioavailable (medicine getting into your system) than the original medication. I have seen people who are on two 30 MG Oxycontin per day, for over a year. Then, as soon as they picked up their prescription (Oxycontin OP), with the new formulation, they are NOT getting nearly the same relief they had with the original Oxycontin. You must write Pharma-Purdue and the FDA to tell them how this new formulation is not working for you.

I have tried changing to Opana, but the patient's response isn't as good as it was with the equivalent (15 MG) dosage. So, what has worked for me is, upping the dosage by 10 MG for those who continue on the new formulation of Oxycontin (OP). This has worked for all of the people I have recorded to experience poor effectiveness (bioavailability) of the previous (original) formulation od Oxycontin.

Again, if you want to convert people who are "abusing" drugs, go to a different site! At least this is an open forum for those who are able to discuss, honestly, what they do with their own bodies and you should keep it as safe as possible for them. Instead of posting your conservative, self-righteous opinions here, go to church, or work at a community drug abuse program. Put your actions where your mouth is.

I am not in any way advocating people to misuse any prescriptions, but if they choose to do so, this forum should be open, accepting and helpful to those who choose that path. If you shut them down, their lives are in more danger.

To summarize, I have changed people to Opana, however, they are not getting the same results as with the original formulation of the Oxycontin they used to take. If you fall into this category, then ask your physician to up your dosage of Oxycontin (if possible), or prescribe other medication for breakthrough pain.

It is a FACT that the new Oxycontin is NOT as effective as the original formulation and the manufacturer will have to address this problem. Thank you for not making those people who abuse any medication, feel bad about themselves. Just try to make it as safe as possible and allow them to be open and honest.

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@vikinpainC, don't be offended when the Dr. says you are addicted. I think dependent is probably a better fit. Your body does require a certain level of narcotics after it's been ingesting some for such a long time. 'Addicts', from my opinion, are people that are using narcotics for recreational use. But regardless of which word you use, your body was/is reliant of your meds to keep from having w/d's.

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Stop it, there is no propoxyphene in the new OP's. I've heard it all now!!!

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Please go to another Doctor that listens to you. I have finally found one that listened to me and took almost an hour with me. Go on the internet and research your nearby pain management doctors, go to the office and look what kind of patients are waiting in the waiting room and you can get a feel if the Dr is in it for the money or for the passion. I'm from Florida where people come here for the pills and then sells them. If you don't like you Dr, find another and keep at it until you are happy. Don't let them bully you around because they are afraid of losing there license.

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Oh I know, I was in Kentucky last year for a few months on business. They call I-75 the Oxy highway! Sux's that the abusers make it more difficult for the real people like me in horrible pain each day to make it more stressfull to obtain our meds just to keep plugging along. It will get to a point that they will have picture ID's to obtain meds which isn't a bad idea to begin with.

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Can you tell me the name of the pain mgmt dr you are seeing? I would really apprciate it! My dr has had me on 90 mg morphine daily and now she is freaking out because of people that abuse it! Those people really make me mad because I finally felt like I finally had gotten my meds straight after 2 yrs and now all my meds are being messed with. sincerely,

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a 40mg opana pill put my 20 year old son to sleep and he never woke up. please be careful out there. he was taking it for recreation, he was healthy and not in any pain. i am so devestated and confused. they said if he obviously had no tolerance for opiates. how devestating

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Blondi
I feel compelled to post this. So you want to die "high". How very sad. You are missing something deep in your soul and that is a relationship with Jesus Christ. Oh, I'll get hammered for this, that's O.K. We all have pain and problems, but a personal relationship with Christ will give you a peace that is beyond measure. There is a wonderful freedom in confessing your sins, coming before our Lord with a broken and contrite heart. In that you will find peace, grace and salvation and joy.

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MANY who have no "junkie" issues, developed addiction problems only after taking MEDS for legitimate injuries! & anyone who takes a narcotic pain med(s) will be addicted, that is just a fact ! But for a DR. to say ur addict, is correct ! I've never abused my MEDS, & my body is dependant on the RX, & my mind has been affected in the same sort of manor, so, I could be considered or tabled a "junkie" ! Be informed, be understanding, be compassionate, understanding now that Ive given u some food for thought, ok ! don't be so quick to judge, as u can't hold a man down, without staying down with him ! Use ur knowledge & experience to assist/help others, not "BLAST" THEM, CUZ IF UR ON NARCOTICS, ESPECIALLY FOR AT LEAST A FEW MONTHS, THEN U URSELF COULD BE CONSIDERED A "JUNKIE" ! PEACE BE TO U "BROTHER" !

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I have taken Large doses of Oxycontin for 10 years now, Recently i was not able to get any more Oxycontin OC brand the OP Oxys made me very sic, Thats another story stay away from them. Anyway the day came this month and i had no choice but to try a new medication and thank god i have one of the best pain Doctor that truly cares and works with the person, The Opana is a wonderful medication as soon as i started taking it there was no problems,if you take 80mg Oxycontin people and the pharmacys claim that Opana 40mg is the same as Oxycontin 80mg, Wrong its about the same as a 60mg Oxy, Two 40mg Opanas will work As good if not better than one 80mg Oxy and no side effects or withdrawal, Its been a week now and my days are better and i know what to expect from the Opanas, every person is different so each has to try the meds to see what will work best, Opana wwill not last 12 hours because of my pain and Oxycontin never did, I get about 5-6 hours and need another dose to maintain a low pain level,and also use breakthru meds in between and im more happy with the Opanas then i was with Oxycontin, As long as people dont try abusing this medication alot of people in severe pain will have better days.

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Suboxone is an opiate blocker. I dont understand how morphine would help at all if the suboxone is blocking your opiate receptors

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NICK, I'm allergic to MORPHINE, So when I could tolerate OPANA'S, I naturally assumed they contained NO MORPHIN, & if Iam wrong, then I was misinformed! I'm not too big that I can't admit if so ! Being wrong is not a big deal ! NICK, info assimilated, thank u for ur input !

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GUNNEY:

It's nice that other posters in this forum can cut and paste from Wikipedia, but the answer you are looking for is, Oxymorphone IS NOT Morphine, or made from Morphine. This is why you are able to tolerate Oxymorphone and not Morphine. They are two, totally, different medications (chemical compound).

Oxymorphone is approximately 10 times more potent an analgesic on a weight basis when compared to morphine. It has less antitussive activity than does morphine. Don't let other people tell you what you are taking. Just research it on the Internet and you can learn the facts for yourself. I guess some people just like to hear (see) themselves write!

Don't bother with people who are not educated on the chemical make-up of the medications you take. Opana is Oxymorphone, which has absolutely NO Morphine in it. Again, if you are taking Opana, you are not ingesting any Morphine at all.

Good luck and I am sure nobody minds all capital letters.... Seems pretty petty on this forum.

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I am a 28 year old male that has been suffering from a fairly rare condition called Chiari malformation type 1. It is essentially a herniation of the cerebellum into the spinal canal. I've had 2 brain surgeries one in 2007 at the Mayo Clinic in Minnesota and one in 2010 at the University of Minnesota.

I was diagnosed with the condition in 2005 after having an MRI of my cervical spine/head. I met with a few neurologists and neurosurgeons after being diagnosed, after the meeting with doctors I didn't follow up much for over a year. I started to exhibit more and more symptoms as time went on and they became more severe.

In 2007 I was referred to the Mayo Clinic to see doctors that specialize in my condition; the city I lived in at the time had limited to no experience medically with my condition (i.e, how to treat, care for, help, etc.). Meeting with doctors that specialized in my condition was extremely helpful and informative. A month after my initial appointments I was scheduled to have surgery, the surgery was hopefully suppose to alleviate a good portion of the symptoms and excruciating pain.

Let me give you a small background about me, I was very active as a young man in sports, hockey and soccer. I was active in hockey for more than 14 years, traveled around the country and played in Canada for 3 of those years. Needless to say I've broken a few bones and have had a few surgeries so I got familiar with a few different narcotic pain medicines. Vicodin, Lortab, Norco, Lorcet (those are all Hydrocodone with acetaminophen varieties) and Percocet (Oxycodone with acetaminophen). Although all of the Hydrocodone varieties are made of the same FDA approved medicine I noticed each would effect me differently.

I had decompression surgery for Chiari malformation type 1, they removed portions of the back of my skull to create room for the tonsils of the cerebellum that had herniated out of the foramen magnum. This is when I was first introduced to Oxycontin and Oxycodone IR (immediate release). When I was in the hospital for surgeries, as well as this one, I received morphine, dilaudid, fentanyl and other similar short acting strong narcotic pain medicines through an IV. Anyway, everyone is different and reacts differently to medication. Although, it does seem for most people that Oxycontin works great for long term around the clock pain control for just about most people; before the reformulation to OP of course.

Since having surgeries to help my condition I've been on just about every type of narcotic pain medicine, long acting and short. Fentanyl transdermal patches along with an immediate release pain medicine (usually, Oxycodone IR 15mg) for break through pain works the best. I've tried dilaudid 8mg (highest dosage) but oddly enough they do absolutely nothing, like taking a placebo, literally no effect which sucks. I've tried different dosages of morphine (MS Contin and generics) with no success even on really high doses.

Recently my pain doctor suggested that in my case a lot of his Chiari patients use Opana along with a break through medicine and Topamax with great results. Currently I am taking Oxycontin 80mg OP 2x a day I switched down from 3x a day not because it works better (actually is by far less effective in the reformulation) but because I wanted to try taking less along with Oxycodone IR 15mg 4x a day (taking less of this as well). It works not effectively but I am making it through, for the most part, but I've been reading on here that Opana seems to be a pretty good fit for a lot of people so I'm a little excited to give it a try.

I would go back on the Fentanyl patches but I really don't want to go down that road again they were quite difficult to get off of. Right before my second brain surgery I was on a ridiculous amount, 100 mcg/h transdermal patches and 50 mcg/h transdermal patches with break through pain medicine AND a dilaudid pain pump that was delivering 1-4mg every hour that I could change. Pretty much lucky I didn't kill myself I actually did pretty well with it all. After surgery I was on 80mg OC Oxycontin 3x a day, Oxycodone 15mg IR 6-10x a day AND the dilaudid pain pump giving me an infusion of 1-4mg an hour but I changed the settings a lot an would some times give myself 2-4mg infusions when I was feeling squirrely, hehe.

You may be wondering what I'm talking about when I refer to the pain pump. I had a picc line that went into the side of my left arm on the side of my bicep and i had 100 mg bags of dilaudid (hydromorphone) delivering infusions/intravenous doses of the medicine. The hospital released me with it a few different times before and after brain surgery because of my situation. I was in bad shape, weighing only 120lbs, throwing up constantly, lot of time I couldn't take my oral meds an I contracted pseudomonas in my blood, needless to say that's about as sick as you can get pretty much.

I got off in a lot of different directions but keep posting the Opana information, I like to hear how other people are doing on it and how it works for them. Thanks for all the info and help!

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Hello everyone, I suffer from a compression fracture, many compression deformities, scheuermanns disease schmorl nodes kyphoscoliosis, I am 30 years old, I was originaly on oxycontin 40 mg 3 times a day, it was ok for the pain. My PM doctor switched me to opana er 15 mg 2wice a day , wow this medication works so good for pain I can actually enjoy my day. My pain levels are 1-3. on 120 mg of oxy my pain was between 5 and 8. I highly recommend switching from oxy to opana it has changed my life for the better. Peace

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