Incomplete Dissolve And Absorbtion Of Medication
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I started Nifedipine XR 30 mg last Friday, June 10,2016. I realize the tablet shells do not dissolve but I think the entire pill with the undissolved and unabsorbed medication is passing through my system. My blood pressure has not gone down since I started it 6 days ago. I happened to swallow a dental crown the same day I started the medication and have, unfortunately, been trying to retrieve my $900 crown so that I will not have to buy another. In this effort I have found 4 pills, each time thinking it was my crown, and upon inspection found the yellow medicine still inside each pill. My doc says I have absorbed the medicine but told me to double the dosage to 60 mg/day and was insulted when I mentioned the pharmacist told me to ask for a different medication. I have before and after pill photos if that helps answer this question. Thanks for any help in solving this.

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I have had my 90 mg pill not dissolve over the past 2 days. I actually saw it the first time in my stool, and the one the next day (yesterday) didn't dissolve. I absolutely know this because I have taken this drug for years for Raynaud's Syndrome and my fingers are white again today. I don't think I have drank much water the past few days and wondered if that could be the problem. In all the years I've taken it, this is the first time it's been an issue. I know how my fingers and toes react when I forget to take it, so I know positively that it didn't dissolve these past two days. Any advise on what to do (eat or drink?) to help it dissolve? Thanks.

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Thank you so much for your answer. You are the only person, from doctor, nurses, pharmacists, who has been able to give a detailed explanation. I will continue taking and hope it works.

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The substance that you are seeing inside the shell of the pill is actually part of the time released mechanism, so it not meant to dissolve. Basically, it slowly absorbs some stomach acid, or beverages you drink, to force small quantities of the medication out of the shell over time.

As to not having any change in your blood pressure, yet, it takes about 4 to 5 weeks for such a medication to reach its full level of efficacy in your body to see how well it will work for you.

The FDA lists its typical side effects as possibly including nausea, dizziness, headache, increased urination and hypotension.

Is there anything else I can help with?

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