Hydrocodone Ip 115 (Page 4)
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My pharmacy just switched to the Avkare brand of Norco 7.5. The imprint on it is IP 115. I feel like these do not work at all for me. I would like to know if anyone else that are on these or ever have been on them can let me know how it works/worked for them.

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Re: Chad K (# 9)

Holy crap, who are they helping doing this? I can tell from taking pain meds for a few yrs due to back problems that the hydrocodone doesn't work as well as it used to and something has changed with the meds.

I've been told it's because the body builds tolerance, bla, bla, bla.....But this info proves it's the meds that have changed for the worse.

What can us that take these meds for relief do about it and stop these pharmacy companies and the dea or whomever is letting this happen?

It's us the ones who go to the dr and play by the rules who are getting screwed. All because the street dope heads.... it makes me sick and disgusted.

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Re: Chad K (# 9)

I'm very interested in your work on this subject and would like to see and read more, if possible.

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Doesn't seem to kill the pain as good as the ones before but the search says the potency is the same.

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I too just got my script and it had lp 115. Yes, they don't work! I had to Google to see what l was taking even though my script said Hydrocodone / Acetaminophen 7.5-325. Wondering if the hospital pharmacy can change them?

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You are definitely not imagining this nor are you "growing tolerant" of your med. The problem you have, like almost everyone on pain meds has had in the last year or two, is the DEA / FDA letting them sneak in unstudied clinical trials on these "anti-abuse" additives, and laws that govern quality all at the same time. I will briefly explain; I am a masters level chemical engineer with a minor in biochemistry and polymers so this is all factual information based on over a year of personal research and lab tests. If you would like sources, or to see some of the pictures/results of my tests on these pills please ask; I think people need to know the real problem.

First off, generics are now allowed to vary by 20% coming in with the schedule-II change, it was more readily taken advantage of by the greedy pharma companies like norco. They bought out many smaller companies, a study done by a team at Vanderbilt in 2016 found on average the norco 10mg pills contained only 8.4 mg of hydro (within 20% being above 8). Does anyone else feel ripped off yet? Isn't a 20% tolerance extreme when it governs a medication? Why only pain meds? A 20% deviation in BP med or insulin could be deadly, why not deviate above as well? If you only take approx 8 in a 10, every 4 pills made the savings, makes a 5th for free. Scale this up to nationwide sales, that's millions more for them at our expense. If you get 60 pills, in reality you're only getting roughly 48 10mg equivalents; you were just shorted 18% of your prescription.

Next: hydro is salted with bitartrate, where 98% of other meds are simple hydrochloride salts. This matters because HCl is very little weight added, where bitartrate is a 4 carbon, di-carbonyl-di-hydroxyl sugar acid. In simple terms, the hcl is less than 35 g, but the sugar acid with its 6 oxygens and large structure weighs in at 149 g. This is a THIRD of the hydro weight, so saying 10 mg of hydrocodone bitartrate is actually saying 3.4g bitar and 6.6g hydro. Now apply this to the already lessened generic of 8.4, we're now at 5.6 mg hydrocodone in a "10" mg pill....now do you feel shorted? That's almost half!

Last and most important is the new anti-abuse additives. It used to be just hydrocodone, acetaminophen, and a bit of necessary but harmless fillers like silicon dioxide, possibly a touch of starch (starch is a complex sugar such as in potatoes) which is digestible. Now, up to 8 man-made polymers are added to prevent "abuse". That's great... In a way...laws cant outlaw people from making bad decisions. For the ones still at it, these new water-soluble plastics are completely unable to be broken down by our bodies and will prove MUCH more fatal in the blood than the act alone prior to this act to "save the abusers". PEO is in many pills now, PE (polyethylene) is the plastic coke bottles are made of. Povidone and crospovidone are in most and will be in all by 2019 if no one objects. These are pretty, shortened names for some nasty synthetic polymers designed specifically not to release the med into a water solution preventing inj... They dont tell you this also means that it prevents proper absorption, not to mention "cross-linked polyvinylpyrrolodone" (the real name of crospovidone doesnt sound as harmless) is a rubberized form of povidone (polyvinylpyrrolidone) and is present along with the water-soluble un-rubberized form, along with modified cellulose (hypermellose), stearic acid (nice way of saying soap), and several others.

I've already written much too much, but I separated, purified, and analyzed most of these polymers myself. The results were horrifying. Piles of goo resembling elmer's glue, sticky slimy substances that would be extremely difficult to pass through the gut, unsoluble crospov. ball of slimy rubber, glassy-brittle plastic crystals of PEO, ALL of which are completely unable to be processed by our bodies and block absorption. I have pictures and great in-depth detail of this matter if anyone cares to learn more. If just one person hears the truth, all my dedicated time was worth it. I hope this clarified some of your concern. Bottom line, this control has gotten out of hand when our meds are cut and health patients are actually put at risk for some companies to make a little extra money.

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Hi Julie, I believe that if u ask the pharmacist before they fill it they can get a different generic but it depends on the pharmacy and the script. Ask ahead of time. I know the type of Rx is different but for my stop smoking patches they were able to give me a different generic bc this first patch irritated my arm. It's kind of the same thing if they aren't effective for you then they should be able to give u a different generic.

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Thanks. Best of luck to you to. Hope you find something that works.

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I will definitely do the same. Thank you for your opinion, I know now that it's not just my imagination. Thanks, best of luck to you.

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At my pharmacy they said it's what their supplier has that they can get in. I might see if my doctor can write on my next script "no Amneal/AvKare".

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So it's the pharmacy and not the doctor that decided on this medicine? I guess I'm stuck with this crap for at least the next month right? Ugh they do not work for me and I feel so tired all the time.

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I told the pharmacy tech that I hated these ones and she said she hears that from people a lot. They still don't work for me so if my pharmacy can't get a different brand then I will go elsewhere

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Hi Maria, I was also taking the same madication as you and was given the IP 115 this time around. I agree that it just doesn't seem to work as good on the pain, not sure what the difference is since the bottle reads the same dosage as my last prescription. I kind of thought it was a mind over matter thing for me since it's a different looking pill then I read your statement, just wondering how you are doing now with them since it's been a while.?

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Hello, Maria! How are you? Has there been any change?

As permitted by the Hatch-Waxman Act of 1984, there can be fluctuations in generic medications. They are allowed to differ in the amount of the active ingredients by as much as plus or minus 20% of what's in the name brand, additionally, they do not have to measure against each other, only against the name brand.

Thus it is possible that this one is a little lower than the prior one you were taking. However, since the differences are slight, most people adjust within a week, or so.

The FDA warns that this medication carries the risk of being habit forming and may cause side effects, such as nausea, dizziness, headache, dry mouth, and constipation.

I haven't had any problems with their products, but I can only speak for myself, and it's been years since I took their Norco.

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