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Hydrocodone And Divalproex Sodium Safe To Tske Compazine

Updated February 28, 2012
Mika Says:
Wed, December 21, 2011

I'm currently taking 500mg hydrocodone/apap every six hours for pain plus 250mg divalproex sodium twice daily. Is it alright to also take 10mg compazine for nausea or are there any side effects I should be aware of?

1 Reply

1
Verwon Says:
Tue, February 28, 2012

What has your doctor advised?

Generally, it is listed that the Compazine should be avoided with both of the other two medications.

https:/­/­rxchat.com/­wiki/­Compazine/­

When combined with the Divalproex, it increases the risk of depression of the central nervous system.

https:/­/­rxchat.com/­wiki/­Valproate_semisodium/­

And with the Hydrocodone, it can increase the chances of that, plus it can cause severe constipation issues due to paralyzed bowel.

https:/­/­rxchat.com/­wiki/­Hydrocodone/­

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