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How Long For Iv Morphine To Wear Off

Updated May 16, 2015
Jen Says:
Fri, May 15, 2015

They gave my mom 4mg of morphine in her iv. How long do the effects last,

1 Reply

1
David Says:
Sat, May 16, 2015

Hi jen,

According to nhtsa.gov, morphine is said to have a short half-life of 1.5 to 7 hours. They go on to note that close to ninety percent of a single morphine dose is excreted through urine within 72 hours.

However, on the contrary, a different report coming from nih.gov states that morphine has a "plasma" (blood) half-life of 2.5 to 3.0 hours. So when it comes to IV administration, this is probably the half-life I'd refer to for a more accurate estimate.

Though this is mostly speculative, it's been thought that after 3 half-life's, a medication like this is typically out of your body / no longer working to relieve pain.

There are also other important factors that can determine how long a medication remains in the body (such as weight, age, metabolism, diet, other medical conditions, etc). So this is just something else to keep in mind as well, considering that the figures above are only intended to be rough estimates. But my theory is that the pain relieving effects probably wouldn't last more than half a day, if that.

I hope this helps!

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