How Long Does It Take Zoloft 50mg A Day To Start Working

started on 50mg zoloft one wk ago exactly for depression. having a few side effects from it but dont feel any different, how long b4 it starts working?

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Hello, Single08! How are you?

It usually takes about 4 to 6 weeks to reach its full efficacy level in your body, so you can tell whether or not it is working for you. You'll be able to tell, because it will be around the same time that any side effects you experience hit their peak intensity and then start to taper off and slowly go away.

Typical side effects to this medication may include nausea, dizziness, headache, dry mouth and weight changes.

Is there anything else I can help with?

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