Fatigue After Amoxicillin Cessation

Hello, and thank you for being there.

My wife had been taking a course of amoxicillin for cystitis but stopped yesterday and today feels terribly weak, with occasional hot flushes and pain below her left shoulder blade.

She is a 73 year old 'Anglo-Saxon' weighing about 110 lbs. She has not lost any weight, but her BMI has been low for years despite all attempts to build it up. Her height is 5'7".

The dosage was 12 x 500mG pills on the first day of the course and one 500mG pill a day for 16 days, total 28 pills. She had nearly finished the course but stopped because her skin was yellowish and her urine was darker than usual although bowel movements were normal in colour.

Her skin is improving in colour ; pink is beginning to replace the yellow ! FWIW she'd had a sore throat for days and speaks weakly today because of this and the tiredness. There do not seem to be any psychological effects.

Is this awful physical weakness a known effect of stopping taking amoxicillin, please, or should she see a doctor in case another physical problem is occurring ? We're located in rural (Old :) England.

Many thanks in advance for your help.

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Yes, she should see a doctor. The yellowing of her skin usually indicates jaundice, which may not be a serious problem, but once in awhile, it can indicate liver damage, liver disease or liver failure. The weakness could also be a sign of that, according to the NIH, so it would be best for her to have herself checked out. The doctor can easily check for any problems via some simple blood work.

Is there anything else I can help with?

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