Endocet Vs Oxycodone (Top voted first)

I HAVE BEEN ON OXYCODONE FOR OVER 2 YEARS AND MY DRUG STORE RAN OUT AND GAVE ME ENDOCET? SAID IT WAS THE SAME THING BUT MY BODY TELLS ME THAT IT'S NOT THE SAME. HAS ANYONE ELSE HAD ANY PROBLEMS WITH THIS CHANGE?

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Dowhatucan2stop! Even if you buy brand name percocet it will say oxycodone HCL 10mg=8.9637, this is because of the salt you know the HCL is a complex salt. So even with the brand name your are not getting a pure 10mg of oxycodone. This is with any narcotic that contains a complex salt. The salt helps in the absorbtion process in the body and metabolites. You are assuming because on the endocet bottle it says 10mg of oxycodone=8.9637 of oxycodone you are getting shorted on the opioid, this is your junkie mind spinning its wheels. Percocet and endocet are the same, you are getting the same ammount of the oxy, however the grade and quality may slightly differ, thus making you feel like you are not as high, or getting the same relief, YOU ARE STILL GETTIN THE SAME AMMOUNT OF OXYCODONE. Good try on being professor of the year award, but not enough to convince anyone with a little bit of sense.

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Well, I am not sure what you were on previously, since you just say Oxycodone, but Endocet is a combination drug containing both Acetaminophen and Oxycodone.

The reason you may be having a problem, however, is due to the fact that generic meds ARE allowed, by law, to differ from name brands by as much as PLUS OR MINUS 20%. They also DO NOT HAVE TO BE EXACTLY IDENTICAL.

I know the doctors, pharmacists and FDA will tell you that they are, but this is just not true.

They only have to be biologically equivelent. Which means the active ingredients can be different, as long as they act in the body in the same way and provide the same therapeutic effects as the name brand drug did.

I am sure by reading this, you can guess how with some drugs this can cause a problem as your body is used to once substance and suddenly you might be getting another.

The inactive ingredients can also have an effect on how the medication works for some people.

You might want to speak to your doctor about having them write on your prescription that you have to have the pills that you had before. (Brand medically necessary and have them put the company name on there, for instance Watson if that was who made them!)

In addition if one pharmacy is out of the stuff you usually take, you are not obligated to get the prescription filled there. You can tell them that you are sorry, but the current brand they have does not work for you and ask them to return your prescription so you can get it filled elsewhere.

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1) I've been on both ends: as a registered nurse and also a 'chronic' pain patient. Meaning my pain is not daily but recurring monthly for up to 10 - 12 days per month. I've never had a drug addiction problem but my body does respond to this 'back & forth-ness.' I write everything down for my own recording - because if I'm not careful I will sometimes experience physical symptoms of withdrawal for up to 4 days. Even if I taper down correctly......2) Verwon is right: Inactive ingredients will not always but **can** affect how a patient experiences medication. Factors vary but they can indeed get in the way of effectiveness. And generics are **not** all equal. Trust me when I say Big Pharma, the FDA, pharmacists, nurses & doctors are not all on the same page. They're not gods, only human and this means not perfect. Some pharmacists (our best resource for drug information actually - they know more about what should be happening, the ideal and also detailed drug information more than MD's) -- but some do know about this difference. Others are in denial or just brainwashed in a way, for lack of a better term. Just like other health professionals (including nurses)..... 3) I've experienced a few different brands of generic oxycodone/APAP & also brand name Percocet. Tolerance build ups notwithstanding, there is **definitely** a difference between brand & generic as well as generics themselves - re effectiveness and sometimes side effects. Again, factors vary. People who rarely take this kind of an Rx tend to be more sensitive and less likely to notice any such differences in terms of effectiveness. Percocet 2.5 can hit 'infrequent-flyers' like a big stone on the head. Vs. someone like me, 2.5 would not touch my pain at all (even my regular physician was horrified when I returned from a vacation once many years ago. Because I I'd had a very messy emergency and the clinician at the walk-in facility prescribed 2.5's after treating me. My doctor back home was actually very upset, almost called her. And I digress).....Anyway, this is based on my experience with med-surg in-patients reporting to me as well as my own personal feedback.....4) Since my Rx schedule is fairly regular and again, I'm aware of the tolerance factor, I believe I can tell the difference (subjective, of course) between the generics.....Last time I went to the pharmacy I was given Mallinckrodt oxy/apap 5/325 (4.48 mg oxycodone hydrochloride/325 mg Acetaminophen) and a few other times, too. I always go to the same pharmacy for this when in my current home city and they will also use other generic brands. Long way around to saying that in my experience Mallinckrodt is not as effective as others..... 5) There is no way any of us can know what goes on during manufacturing outside of inspection times. I still believe most people are good but all pharmaceutical companies are businesses and they want to make money, profits (we're talking billion$$ in the double digits + for them), same as most of us need to. Only they are not always 100% honest about what goes into pills & capsules, side effects, true effectiveness, etc. Google it, there have been lawsuits.....6) Re what Woodstock 2009 Says and only to clarify: Hydrocodone combination products are not as strong as oxycodone. Typically it is that 15 mg of hydrocodone mixed product (example: as in when blended with acetaminophen) is about the same as 10 mg of oxycodone. Less oxycodone blended product (per mg) is needed to get the same relief **if** they both would work at some dosage for a person's pain. Last I checked oxycodone + it's blended products are Schedule 2, 'plain' hydrocodone is also schedule 2. Hydrocodone blended products are Schedule 3. And if anyone is wondering, something like heroin is considered a Schedule 1 drug......7) Best to have your MD write a prescription so that you have a free & clear choice between brand name or generic.....8) It's kind of crazy sometimes from my perspective - because I'm trained to recognize drug seeking behavior so I'm always of 2 minds. To be honest (& so very human!) it's hard not to get a smidgen paranoid when I have to advocate for myself. When I once needed to ask a pharmacist about something related I could see the red flags in his eyes. He was polite but I could see & feel what he was thinking. Then twice in the last 3 years I had to go to the ER at a local hospital at night. I told the hospital physicians about my regular Rx (which I was in between) and comfortably it seemed, both times, they went on and prescribed pain meds. This was appropriate. But when I next saw my doc & told him it was very stressful. He was not thrilled but was really okay about it in the end.....At another much later time, after seriously delaying the reporting of feeling under-medicated: suffering motivated me to finally get honest and advocate for myself. We had a long discussion about the tolerance - dependency- potential addiction aspects and he said was not worried. But, naturally, he was now aware of this change Which is what should happen if a doctor is diligent & true. He did increase the number of tablets of my prescription. But I never want to experience that again.....10) In my 'world' there is a cure for all adverse medical conditions. They just have to be uncovered. This is my sincere belief. I've also been trained in the use of a short list of holistic treatments and make use of those for myself as well. combining methods can sometimes help. My doctors never mind this as long as I am not being harmed. I consider an integrated, holisistic approach to my health care since there is no legitimate need for modalities to be at war. Any MD or NP who is trained and experienced in additional therapies knows this.....I intend to be well - so to not need narcotic medication for the rest of my life. Incidentally, I do think that these kinds of strong, narcotic Rx's will be a thing of the past sometime within the next 100 to 150 years. That new discoveries & understandings will naturally allow for this. Until that time (and after, too): making use of our resources (including experienced, smartly educated professionals) & **self-education**, self-advocacy -- and no one being alone in this -- these things are key. The medical model will be very different in the next century and that will be a blessing for everyone.

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Listen I don't know what you guys are talking about but I take percocet and endocet 10/325 and its the same pill and gives the same affect. If you get a prescription bottle for each from the manufactor endo pham. Makes both products the only difference is what is printed on one side of the pill. Percocet says 10/325 on one side and percocet on the other, and endocet has 10/325 and E712 on the other. Its all in people minds that they think its not the same because there difference names but in reality they are two alike.

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Was on Watson 10/325 oxy. Made the mistake of taking script to different pharmacy. They filled the script with endocet. I realize it's the same drug, but the generic Watson seemed to be much stronger. Just my opinion. Thanks for all you're interesting posts.

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All of you are incorrect, to an extent...even those of you who claim the amount of oxycodone in generic is allowed to be up to 20% off from the name brand manufacturer. I have in my hands, my latest prescription for Endocet 10/325. They DO in fact differ from Percocet not only in strength of pain relief, but also in PRICE. You will make a grave mistake if you have you Dr. write either medically necessary or name brand only on your scrip, because the cost per pill for brand name Percocet without the best insurance available, which I guarantee the vast majority of you do not have, is roughly $6.00 per pill. If you are fortunate enough to have very very good insurance, you will pay 50% of the cash price for the script....that is just simply the way these pharmacies work. So, on an order of 120 count 10/325 that your Dr. has written the above words, you will have a minimum charge of roughly $360.00, which is 50% of the cash price because Percocet is NOT considered a preferred drug....whereas several hundred other drugs are considered preferred and you would simply pay the $30.00 for the name brand. Trust me, crappy experience once you get to the pharmacy and find this out. Even worse is the fact that now, unless you find a wonderfully understanding pharmacist and they are willing to actually bend the law...your script is WORTHLESS. The pharmacist HAS to fill it as it is written. So-on to the generic strength vs. the name brand. My bottle of Endocet, which by the way is DIRECTLY from the manufacturer, clearly states the ingredients...read and weep=Each tablet contains Oxycodone/Hydrochloride, USP.....10mg* and Acetaminophen, USP.....325mg. Notice the * next to the Oxy dosage. Follow the bottle down to the very bottom and in VERY fine print, the * represents something else-Quote*10mg oxycodone HCI is equivalent to 8.9637 mg of oxycodone. Bottom line, PERCOCET is a full 10mg of oxycodone. THERE IS A DIFFERENCE.

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in reply to jim, i have to agree, i have been taking oxycodone for a while now, and got a new script for endocet, and it does not do anywhere near as much as the last prescription did...

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To Zgglof: I called & talked to the company that makes the endocet for Endo pharmaceuticals ( Vintage Pharma.) & they have listed in their side effects not listed on paper you get from the pharmacy, THAT IT CAUSES GASTRO INTESTINAL ISSUES. so NO, unfortunately your not wrong. All you people on here talk like endocet is a pure form of oxycodone & it amazes me how DUMB all you junkies are, or either none of you even understand your own complaints, I mean read your posts again your comparing pure oxycodone to Percoset or it's generic. Stay off pills unless you need them. I'm going to have to pay & suffer from chronic degenerative pain while you all are getting your drugs off the street. Cant you just smoke a joint or something? Please don't ruin it for us patients that really need it. Peace

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I have been taking percocet 5 mg pills for a month and was ungraded to 10 mg 325 for pain. The pharmacist gave me endocet and let me tell you it does not work the same as regular percocet. When filling your script make sure you ask for brand name percocet and don't get stuck with endocet, its sucks. I had to take 3-4 times as much to feel the same as normal percocet. Everyones body is different but alot of other people have agreed with me, I wish I would have known this from the get go. Hope this helps

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You are right, my mother has degenerative disc disease as well as polymyalgia, and even if she could get a script for the meds she needs, the insurance companies won't fill them. So, as a result, on those days when she can't walk, can't sit, can't lay down, she SUFFERS (and those days have now gotten to be the majority of her days as her condition continues to deteriorate). It has gotten to a point that now EVERYONE who uses an opioid pain medications is basically classified as a drug addict, and that many who suffer from debilitating, chronic pain can no longer find adequate relief for quality of life (and note, I did NOT say "pain-free" quality of life since most who suffer the worst don't even expect to be pain free....they just want to be able to FUNCTION!) ALL we EVER hear through media is about the overdose cases, and they are TRAGIC, no doubt, but they are THE MINORITY of opioid pain med users, and we NEVER hear about the thousands and thousands of chronic pain sufferers, like my mother, who can no longer get relief, who has been sentenced to an inhumane existence for whatever time she has left on this earth because someone has decided that she can't have the medication she needs, that she isn't responsible enough, that because someone's son, daughter, parent, husband, wife, sibling, friend overdosed, so will she, and if 3 pills a day aren't enough, TOO BAD, SUFFER! Somehow, the other side of this story has to get out there, has to be as prevelent as the stories of tragic overdose are. We, as a society, MUST put as much value on the ppl still living on this earth, trying to deal with terrible chronic pain, as we do the lives of those who, for whatever reason, could not handle their use of opioid pain medications. To make those still here, still suffering, pay for the mistakes of those who overdosed (though that is tragic) is UNFORGIVABLE!

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I began taking oxycodone 10/325 for extensive dental work. I had 3 scrips filled... First was the long white oxycodone, second was the round circle oxycodone, and third was the Endocet. The round oxycodone worked the best for me and had the fastest and most consistent results. The long white oxycodone hit me like a ton of bricks the very first time (not much of a pill taker), but never got that feeling again with them... maybe if I didn't eat... The Endocet takes over 2 hours to start working and makes me itch like crazy. I am now on percocet 10/325 due to extensive nerve and spine damage... I ONLY take one pill per night before bed to help function during the week, and nothing on the weekends. I intend to stay on this system for as long as possible (I went 11 months without any insurance and no help w/ pain and didn't realize how much pain I was in until the dentist prescribed them to me). Anyways, I rarely take medication, in no way abuse these pills and I notice a difference in them. The Endocets irritate me enough that I will be ensuring that I do not end up with them again, but the oxycodone... I will take the long ones one an empty stomach with a cup of milk... and the round ones are great, so either/or, I'll make it work.

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Endocet doesn't make you itch because it is not the same as the Oxycodone. The insurance companies tell you they are equivalent - but they aren't. I didn't have any of the usual side effects with Endocet that I had with Oxycodone. But I didn't have any of the pain relief, either.

My pain management doctor told me that he frequently hears from his patients that Endocet doesn't work for them. He also said that generics can be up to 25% weaker than the original drug, and still be called "equivalent." He destroyed my Endocet and gave me a new prescription for a better brand of Oxycodone. Problem solved for me.

And as for the people on this thread who want to lecture others about taking these drugs - don't comment on what you don't understand. Not everyone who uses these drugs is doing so recreationally, and not everyone who uses them legitimately becomes addicted. I am a terminal cancer patient and I need this medication. I have been on the same dosage for 2 years and have never needed or taken more. Stop judging others when you don't know their stories.

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Very well said. I had cervical spinal surgery. Surgeon perscibed percocet. Pharmacy filled it with endocet. I got absolutely no relief. Endocet sucks. I paid full price for percocet (non generic) Changed pharmacies with subsequent script. New pharmacy said they don't use endocet and filled with oxycodone.
Finally got relief. The medical system is screwed up.

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I'm sorry for your loss. I can't imagine how losing a child must feel. But, I am currently being treated at a pain clinic. I take my medication as prescribed. If I wasn't ever able to get my meds for pain I would definitely commit suicide. I wouldn't be able to function or have any quality of life. So, you saying these clinics should be closed down would be catastrophic for a lot of people.

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Dowhatucan2stop here is the dosing information from the official website, I think you will enjoy this

PERCOCET®
(oxycodone and acetaminophen) Tablets, USP

DRUG DESCRIPTION
Oxycodone, 14-hydroxydihydrocodeinone, is a semisynthetic opioid analgesic which occurs as a white, odorless, crystalline powder having a saline, bitter taste. The molecular formula for oxycodone hydrochloride is C18H21NO4•HCl and the molecular weight 351.83. It is derived from the opium alkaloid thebaine, and may be represented by the following structural formula:




Acetaminophen, 4'-hydroxyacetanilide, is a non-opiate, non-salicylate analgesic and antipyretic which occurs as a white, odorless, crystalline powder, possessing a slightly bitter taste. The molecular formula for acetaminophen is C8H9NO2 and the molecular weight is 151.17. It may be represented by the following structural formula:





Each tablet, for oral administration, contains oxycodone hydrochloride and acetaminophen in the following strengths:

Oxycodone Hydrochloride, USP 2.5 mg*
Acetaminophen, USP 325mg
*2.5 mg oxycodone HCl is equivalent to 2.2409 mg of oxycodone.
Oxycodone Hydrochloride, USP 5mg*
Acetaminophen, USP 325 mg
*5 mg oxycodone HCl is equivalent to 4.4815 mg of oxycodone.
Oxycodone Hydrochloride, USP 7.5 mg*
Acetaminophen, USP 325 mg
*7.5 mg oxycodone HCl is equivalent to 6.7228 mg of oxycodone.
Oxycodone Hydrochloride, USP 7.5 mg*
Acetaminophen, USP 500 mg
*7.5 mg oxycodone HCl is equivalent to 6.7228 mg of oxycodone.

Oxycodone Hydrochloride, USP 10 mg*
Acetaminophen, USP 325 mg
*10 mg oxycodone HCl is equivalent to 8.9637 mg of oxycodone.
Oxycodone Hydrochloride, USP 10 mg*
Acetaminophen, USP 650 mg
*10 mg oxycodone HCl is equivalent to 8.9637 mg of oxycodone. THIS ONE IS WHAT YOU SHOULD SEE, THIS IS THE SAME AS ENDOCET, OR ANY GENERIC OR BRAND NAME 10/325 OXYCODONE/Acetaminophen
bEFORE YOU TRY TO BE SMART AND GIVE PEOPLE FALSE INFORMATION CHECK YOUR RESOURCES.


All strengths of PERCOCET also contain the following inactive ingredients: Colloidal silicon dioxide, croscarmellose sodium, crospovidone, microcrystalline cellulose, povidone, pregelatinized cornstarch, and stearic acid. In addition, the 2.5 mg/325 mg strength contains FD&C Red No. 40 Aluminum Lake and the 5 mg/325 mg strength contains FD&C Blue No. 1 Aluminum Lake. The 7.5 mg/325 mg and the 7.5 mg/500 mg strengths contain FD&C Yellow No. 6 Aluminum Lake. The 10 mg/325 mg and 10 mg/650 mg strengths contain D&C Yellow No. 10 Aluminum Lake.

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Lamagonzo, I st your bubble but the RPh on your lable stands for the registered pharmacist who filled your RX. It is not a brand but where the pharmacist is suppose to put their initals for fill the that bottle.

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You don't have to explain yourself. I broke my hip and my pelvis in Iraq and have a very intelligent pain management Doctor, as well as the common sense to use my Meds for pain relief, not to get high. The problem is, for every 1 person who takes narcotic pain relievers for real injuries in a responsible way, there are 20 junky opiate addicts and the country has begin to look at anyone who has to take opiates regularly under a microscope. The people that have doubts were probably addicts themselves at one point or know somebody with a drug problem. That is not us and we don't have to explain ourselves.

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This is not true, YOU ARE WRONG! Please look at the small writing on the bottle of endocet that you have ( theirs a little astric & or * " it says they it has only 8.9637 equivalent of Oxycodone. I'm very disappointed & was my pharmacist when he read that, " saying this number can be up to 20% below the 8.9637 Mg. All generics say this on them only brand name & Watson take claim to having 10mg, in a 10/325 Mg. Percoset. Must be why they are so more expensive than any other generic. This is not to come across as rude, it's a damn shame actually that these greedy PHARMACEUTICAL companies can suck up to the FDA & get away w/ this. It's not right & I will be showing the doctor this. Having been switched from Lortab 10's to these, I was dropped some saying it was stronger & wouldn't need as much, but do the math. The doctor thinks I'm getting X amount of Mg.'s if medication & I'm just not, know one is.

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To:@ Jojo
Not all genetics have the same in active ingredients my friend, this part of you message was the only incorrect part. Endo pharmacuticals actually has the least amount of fillers & inactive ingredients than any other brands, being I'm likely going above most of all of you peoples education level here, I will simply use the example " name brand percoset as opposed to generic Watson brand percoset, their is no dye's in those & also WATSON is no longer, I would still be on Norcos from Watson if they were, yes they still say Watson, but anneal bought them out & as of this last early winter if 2013, they took out the dye only, but us chronic pain patients know better, & being one whom suffers from bad chronic pain the difference was night & day & that month was a very long & painful month. Actavis bought out Watson & also moved to Ireland to avoid paying taxes in the US. I got in touch w/ them during my month of taking the new Actavis made ones & even their pharmacist said the likely didn't study the formula long enough before it's release. This is a big topic online & as well on the same site ( check Watson Morgan formula change ) very sad as I never wanted to go up to oxycodone, feels more like a synthetic drug, being it's actually only a partial agonist, as opposed to hydrocodone, due to it's metabolization by the liver into hydromorphone. This is my first month on Percoset & I get whatever generic is available, & mg. Per mg., it's a better overall pain medicine & doesn't make you all spaced out. So next time your thinking your getting Watson product(s) be sure to think again. Stay away from them, as any company that will move out of the US to skip on paying taxes will certainly skip us on our meds., but they also said that they were told by the FDA & DEA to make the change, if something works & has for years you don't change it, again if it were only the dye the millions that know what I'm speaking of would not be complaining. You see the war on drugs has failed, I believe it never was suppose to have been a winner, just a way to control our bodies & minds, now the new war is on the people whom suffer from chronic pain & also those of us whom love our country & the constitution that made us the great nation we are, but if we continue to let them poison our foods, plan false flag operations to create wars, & to continue to destroy our rights, we will soon be Obamas puppets & all live in FEMA camps. We need to take this country back just like we did w/ the Europeans & by this government shut down BS, it's only to try & make us feel & no " JUST HOW MUCH WE NEED THEM" & if the shut hits the fan, their evil plan will be to take all our freedoms from us. I cannot for the like of me understand shutting down our National Parks, which on average bring in a DAILY 75 million dollars, now that's enough money alone to start paying this so called debt back that was printed of mere paper, it's just paper people. Sorry to get off the subject, but expect lots more changes to come & remember this country was founded by great men that believed in the fact that government should not control the people but better yet we should control the government. Fear is the name of the game. I mean mandated medical care or face punishment & yes even jail. I don't believe that unless we make a change & stop being a nation of obese, & lazy people, than it's off to the FEMA camps & martial law & to those who think I'm just some conspiracy thinker, you will be the first to fall. I LOVE THIS COUNTRY, not one of either sides of my families have not fought the many false wars since WWll. God Bless America & to all those whom suffer from chronic pain I wish the best to you all. Good Luck to you all, Shirley.

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I don't appreciate your comment but in a way understand. I do have cancer and you act if we should be locked away in a hospital to die. I'm sorry for what happened to your son but you don't have the right to say if you're on a fentanyl patch you need locked away . I am on the 25s and have been for over a year. Blame it on the poor judgement of the Dr and don't be biased against us who are actually ill.

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