Diltiazem 180 Er /diltiazem 24 Er 180 Mg

Are these difference medicines or are they the same?

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From what you've listed, they are the same, the second one just includes the 24 to designate that it's to be taken once daily.

The FDA lists the typical side effects of this medication as possibly including nausea, dizziness, headache, increased urination and hypotension.

Is there anything else I can help with?

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