Cytochrome Pathways Hydrocodone

what is it? - cytochrome pathway cp-450; etc

REPLY

REPORT

1 Reply

Hello, David! How are you?

They are a superfamily of proteins which contain a heme cofactor, so they are hemoproteins. They use various large and small molecules in substrates of enzymatic reactions.

Human CYPs are primarily membrane associated proteins that are located in the inner membrane of mitochondria or in the endoplasmic reticulum.

They are the major enzymes involved in drug metabolism, they actually account for about 75% of it. Most drugs undergo deactivation from CYPs, either directly or through excretion from the body. Some drugs can increase or decrease their activity. This could cause you not to absorb enough of any given medication or to absorb too much of it.

A good example to use is the antiseizure medication Phenytoin, since it uses some of the same substrates, if taken with other medications, like Amiodarone or Carbamazepine, it could increase them to toxic levels or reduce them to a level of inefficacy.

Hydrocodone is metabolized via the CYP enzymes.

The FDA lists this medication as being a narcotic analgesic, so it has the potential to be habit forming and may cause side effects, such as nausea, dizziness, drowsiness, dry mouth and constipation.

Do you have any other questions or information to add?

REPLY

Was this helpful? 0

My pharmacy changed my meds from the yellow 10-325 v 3601 norco to the 10-325 white m367 mallinckrodt. I've been tak...

190 REPLIES

Has anyone seen a hydrocodone pill that has u03 on it? ## There actually are white oval-shaped pills marked with U03 tha...

104 REPLIES

Hey, i got these pills today from walgreens and i have taken 3 so far and still no affect on my pain. Has anyone else ha...

95 REPLIES

I am currently on an oxycodone m/r script, and find that it certainly does not last for the claimed twelve hours per tab...

77 REPLIES

My pharmacy just switched to the Avkare brand of Norco 7.5. The imprint on it is IP 115. I feel like these do not work a...

74 REPLIES

I have a prescription for the yellow norco 10 325. I've taken these for years and now I can't get them. The whit...

68 REPLIES

I was put on Hydrocodone for 3 years due to a stroke I had. My pain is coming from the brain. The PM'S started me of...

45 REPLIES

I'm recovering from my third back surgery. I can take hydrocodone/acetaminophen 10-325 mg tab with no stomach proble...

28 REPLIES

Male 210lbs - takes whatever whenever, but is taking over a dozen hydrocodone-apap 10mg/325mg pills in 24 hours. Is that...

26 REPLIES

yellow watson v other side ## I believe you meant to say V 3601, instead of 09 at the end. The yellow pill which you are...

25 REPLIES