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Carb/levo 25-100 Mg For Parkinsons

Updated January 20, 2015
DrPerry Rosen Says:
Wed, July 16, 2014

Are there any generic versions of this tablet either er or direct version which contain different coloring ingredients than the original sinmet product?

1 Reply

1
David Says:
Tue, January 20, 2015

@Dr. Perry,

From what I could gather, Sinemet (Carbidopa + Levodopa) by Merck Pharma reportedly contains the following inactive ingredients:

hydroxypropyl cellulose + pregelatinized starch + crospovidone + microcrystalline cellulose + magnesium stearate.

NOTE: FD&C Blue #2 are also present in the 10mg/100mg and 25mg/250mg dosage forms; whereas D&C Yellow #10 Lake is used in the 25mg/100mg dosage form.

As far as an alternative goes, I did notice that Sandoz makes a generic Carbidopa + Levodopa (w/ the addition of Entacapone) marketed for treating similar conditions, but does have a different list of inactive ingredients:

corn starch + croscarmellose sodium + glycerol 85% + hypromellose + magnesium stearate + mannitol + polysorbate80 + povidone + sucrose + red iron oxide + titanium dioxide. (NOTE: Some versions also contain yellow iron oxide)

Any chance this could be of help?

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