Can These Medicines Be Combine With My Daily Meds. Tramadol 50mg Tablet, And Hydrocodone/acetaminophen 5-500 Tablet. (Top voted first)

Hi; I am taking highblood pressure medicine, Lisnopril-htcz 20/25mg tab and amlodipine Besylate 5mg table. I am taking a blood-thinner called Clopidogrel bisulfate (Plavix oral) 75mg, I also have a vitamin d deficiency so I am taking vit d 50,000 iu d2 (ergo) caps (RX). Can these medicine be taken with Tramadol, and Hydrocodone/acetaminophen 5-500 mg tablet. I am also a predibetic.

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Hi Victoria,

It looks like you posted your question twice within the same paragraph. However from what I could gather, there are a couple serious drug interactions that you should be aware of. The first being between the Hydrocodone and Tramadol combination. Using these two drugs together may increase your risk of seizures, breathing problems, as well as other dangerous side effects.

The other interaction lies between Hydrochlorothiazide and Vitamin D2; which can cause elevated blood calcium levels - relating to side effects such as dizziness, drowsiness, weakness, lethargy, headache, nausea, vomiting, or seizures.

In either interaction, it is very important to talk to your doctor if you think you might be experiencing any complications at all with these medications. You may just end up requiring a simple dosing adjustment to significantly lessen your risk of such symptoms.

I hope this info helps!

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does tramadol 50mg. tablets increase ur blood pressure? Will it or, can it?

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I found over 600 possible drug interactions, 50 of them severe!

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I am diagnosed with Ankylosing Spondylitis. Over two years progressively prescribed Tramadol 300 ER, Lyrica 150mg twice daily, and Vicodin (Hydrocodone 10mg/Tylenol 325mg, two tablets four times daily. Also with BP meds of Lisinopril and Metoprolol Tartrate and Wellbutrin. Over a two week period, episodes of being awake and pre-syncope (semi-conscious) twice daily. On a single day three episodes of presyncope that were pronounced without fully losing consciousness, but alarmingly incoherrent speech and behavioral changes such as eyes and facial expressions that were not lucid but confused. My wife took me to the ER as she spoke with Rheumatologist. Diagnosed as such at a neurological department of urban hospital. Wellbutrin reduced daily over four days until discontinuance. Tramadol immediately ceased. Self reduced Vicodin to one tablet every four hours, with Lyrica every six hours. Condition has disappeared. Some drowziness on Lyrica, but pain is not managed well at these levels and will likely need more of something but will not increase for sixty days. The doctors are calling these seizures. In TX cannot drive for thirty days.

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