Apotex Vs Pliva Trazodone
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My pharmacy just switched manufacturers of my prescription trazodone 50mg. It used to be made by apotex now it is pliva and I am finding that the new pills are having little to no effect and I am starting to suffer discontinuation syndrome. I talked to my pharmacist and doctor and neither one could tell me what was causing this. I was just wondering if there is anyone out there who could shed some light on the subject.

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103

Is anyone currently able to find 50mg Trazodone from Apotex? If so, what drug store? No luck for me so far. Have been taking it for years.

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102

I have taken both and it works the same for me.

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101

Re: JJ (# 98) Expand Referenced Message

CVS and walgeen have Teva which by the way doesn't work for me. I only get 3-4 hrs of sleep. Iloved qualitest but they are not making it anymore and I'm looking for another manufacturer.

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100

Well im tentially about to have the opposite occur my pharmacy just switched to APO

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99

Re: JJ (# 98) Expand Referenced Message

Hi, I'm in Asheville, NC. I've always used Walgreen's for Trazodone until they switched to Pliva (part of Teva) from Apotex on the 150 mg tablet. I found the Apotex at a small independent pharmacy here. Since then, my pharmacist at Walgreen's suggested taking 3 100 mg tablets and 1 50 mg tablet at night, instead, all made by Apotex (my dose is 350 mg.) I am back to normal. So at this point, they carry both Pliva and Apotex. Most of the other chain pharmacies I checked around here carry Teva. Hope this helps!

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98

Re: Marabelle (# 97) Expand Referenced Message

Where are you located? I have the opposite problem—I cannot tolerate the Apotaex version though Teva works fine. My file at Walgreens is clearly marked “Teva only” but three times the pharmacy has ordered the Apotax version, and has not been able to locate a Teva source. I am in the fourth day of a combination of poisoning and withdrawal. Can you help me find a source?

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97

As an update to my previous post of April 17, 2018, I have now switched back to the Apotex brand of Trazodone 150 mg and my uncomfortable symptoms have stopped. It was tough to find this brand in our pharmacies here, most were using Teva or Pliva (a part of Teva, but with roots in Croatia.) One small local pharmacy still carried the Apotex.

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96

After taking Trazodone 150mg, manufactured by, I believe, Apotex (oval pill) for a few years, my pharmacy last refilled my prescription using the manufacturer Pliva (trapezoid pill). Since then, I've been having uncomfortable tummy issues, some dizziness, and more fatigue than usual, which I thought was some other illness. After researching other sites and here, I'm thinking my symptoms may be a result of the new manufacturer. Will talk to my pharmacist and request the original manufacturer to see if my symptoms go away.

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95

Yes I have the same issue: Walgreens uses Apotex or at least that what I got and they are better that the pills I get from Medco Pliva. Pliva doesn't work I'm going to see if I can change.

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94

Re: Marco (# 77) Expand Referenced Message

I took the Apotex for several nights in a row and it did not work. But I did notice dryness of mouth. I went back to Teva and it working well.

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93

Re: Rob (# 90) Expand Referenced Message

I'm so glad I found this site. I was taking 100mg by Apotex for sleep and kept waking up at the same time no matter what time I went to sleep. I thought it was strange that the 50mg worked better. Fortunately, I had refills left on the 50mg. When I checked the mfr., there was a difference. The 50mg was by TEVA. Needless to say, I'm back to having a good night sleep.

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92

Walgreens will also order it for you; they do it for me, and they have a note in my file that says to only dispense Pliva (Teva).

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91

Hi everyone! My spouse was having that same issue with CVS not able to get Trazodone made by Apotex, but check with your local Rite Aid because they can order it for you & they will transfer your current script! Good luck to you all & hope you can get some good quality sleep!!!

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90

I have had the reverse effect. A lot experience didn't work at all and Pliva did. I use for severe insomnia. Is there anyway to find out the exact amount of ingredients in a drug, since the quoted strength can be off 20%. That's 60 mg per dose for me. No wonder I had problems!!. That's another 1/2 a pill.

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89

My pharmacist switched teva to apo it's supposed to be the same. But it is not apo did nothing for me and I as well have withdrawal symptoms. I was fine and now I'm a mess again.

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88

My Walgreens switched from Pliva to Apotex. I was getting horrible canker sores all over my mouth and couldn't figure out why. Went back to the Pliva & the sores are gone. I'm convinced it was the Apotex. It was a terrible experience, sores all over my mouth & couldn't eat hardly a thing for 4 months. Not sure what's in that stuff, but it was not good for me. Also, the Apotex pills are tiny & I couldn't split them well (I take 1.5).

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87

I agree! Apotex takes longer to kick in and I kept waking up resulting in excessive daytime drowsiness! So Walgreen's put note on my script not to give me that brand! Walgreen's is wonderful!

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86

I too, think the Apotex brand of Trazadone not as potent

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85

I am actually experiencing the opposite effect. My pharmacy switched from PLIVA to APOTEX. The Apotex pills do nothing for my insomnia (even when doubling the dose) and I have instead been getting hot flashes at night.

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84

Hi Dorothy: I've been taking .25 mg of Trazodone for over 10 years to sleep (to fall asleep). I've taken many brands: Watson, Teva, Pliva and now Apotex which would be my least favorite. If you can get to sleep without it, do it as often as possible, or else you will be addicted as I am, despite the low dosage. They don't all have the same effect. Some brands have binders or fillers which don't agree with you as well.

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