Apotex Vs Pliva Trazodone (Page 3)

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My pharmacy just switched manufacturers of my prescription trazodone 50mg. It used to be made by apotex now it is pliva and I am finding that the new pills are having little to no effect and I am starting to suffer discontinuation syndrome. I talked to my pharmacist and doctor and neither one could tell me what was causing this. I was just wondering if there is anyone out there who could shed some light on the subject.

103 Replies (6 Pages)

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41

Get rid of the Pliva now,Pharmacys always try to pull this.Plva Is cheaper and full of bad fillers ,the pill Is bigger Isnt It . They will say Its The Same But You know Its Not.. So switch Drug Stores If you have to Apotex Is Made By a Canadion Pharmacy And Is Cleaner!! Don't Take any Lip..

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42

I just want to add that I am having a terrible reaction to the current Pliva formulation. I have no idea what I was taking before this last month, I was in ignorance about the difference in generics until this happened and I started searching on the web - apparently it was from TEVA but may not have been Pliva. Not only can I not sleep, but it has thrown me into a bad depression. CVS says they can't get a brand name product, and Apotex is back ordered for months. They're still looking around for me....

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43

Yes!! Pliva by Teva does not work!! Thank you!! The pharmacists I've spoken to just shake their heads. Until you've experienced the difference, you don't know.

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44

I am in Colorado and I cannot find Apotex anywhere. Pliva which is being sold under the name Teva does not work for me at all. I don't know what to do.

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45

Get On the phone and start calling Drug stores ,You will find one that will get It for you ,..Im getting mine from Thrifty white drug think Its 18.00.But Its worth it Was getting from wallmart but I think they have to comply with government regulations and sell It for 4.00 So If you find It Pay for It .

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46

The Teva version of trazodone is not working for me, either. In fact, I wake up every 2 hours with it, I used to get the Apotex version, which worked well, when I had difference insurance. I have even DOUBLED the Teva dose in desperation, but no luck. RightSource, the mail order pharmacy I need to get it from now says they can't get it, that I would have to get it locally. I have called every pharmacy locally, and no one has it. I've even called distributors to find out where I can get it, but they couldn't give me the info I needed. I've filed a complaint with the FDA about the Teva medication and have spoken with people at Teva, who had me send them a pill. I am FURIOUS about all this. I NEED TO SLEEP.

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47

Read comment #45 You can also find the drug Co. hotline # They will tell you who In your state has It. No one Is going to help you !!

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48

Hello. I came here to learn the difference between Trazodone "Pliva" and "APO". Now I know, and thank you. I saw the Apotex tablets for the first time today. I'm supposed to split the 50mg tabs in half, but boy they look small compared to Pliva. I'll try a 50mg tab and see if I'm loopy tomorrow. I take them for depression, along with Citalopram. Thanks again.

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49

Walmart switched from Apotex to Teva/Pliva a few months or so ago. Teva gives me horrible nightmares and little sleep. Switched to Target for Qualitest which was not as bad...but, now they, too, have joined the Teva band wagon. They tried to order Qualitest for me yesterday, but no luck. I've tried all of the major drugstores with no luck. Apotex was the best, but would have to go to Canada, I believe, to get it. Any updates on Apotex?

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50

We have had a similar problem with our son. Only two manufacturers, Apotex and Mylan, are effective for him. He is very sensitive to the bases in medications and looking at the two pills (Apotex and Pliva/TEVA) will tell you that they are NOT the same. The Pliva/TEVA pill is much thicker, leading us to believe that there is a difference in the base of the pill.

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51

Melissa -- where did you find the Apotex generic Trazodone??

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52

Previously, we have been able to order from Canada, but it is no longer available there. Ask your pharmacist to source it. After I posted yesterday, I did some checking, but was not able to see if it was backordered/discontinued again.

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53

My mail-order pharmacy (Express Scripts) just switched from Apotex to Pliva and I find that the Pliva is very problematic. If I take the normal dose, I wake up feeling drugged, and if I split it in half I'm awake most of the night. Also, the pill is just about identical to another medication I take. I called the pharmacy today, and they said to ask my psychopharmacologist to FAX them a new prescription with "Apotex manufacturer only - no substitutions" on it, and they will order the Apotex for me.

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54

I have already submitted to Express Scripts from my doctor to send only Apotex to me as well. It wont happen. Express Scripts only has the one by Teva and has no plans on getting the older brand. They gave me Apotex's number and the manufacturer also said they were no currently making any.

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55

Update on all Apotex/Trazodone issues. I talked the the manufacturer today and was told they will be distributing the 100mg tablets to pharmacies by mid July. I was told that was the only strength they are going to be making. Whether that changes or not at least there is hope.

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56

Thanks for the update. Hope that actually happens! I'll start calling all the pharmacies in a month.

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57

The only brand of trazodone that works for me Apotex. I am going to call the FDA Compliance Department to report Pliva and Teva as ineffective. I think we should all do that.

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58

With a new rx and a new drug prescription insurance company, I find Trazodone is not working and I can't sleep as well. I believe the new rx manufacturer is not making the drug the same. Dr. believes Apotex (former supplier) is the brand that worked.

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59

This happened in June of 14 as well. I waited 4 months for it to come into stock and then I was able to fill my prescription twice.(2 90day scripts) I called Apotex again today and found out that they are out of stock and their "guesstimate" would be mid May. I was told that same thing before and each time I called they gave me a new date.

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60

Yes I totally agree with you. I recently received a refill of trazodone manufactured by Pliva/Teva. Didn't think much at first but after a while I noticed the med was no longer working. I was only able to get few hrs sleep with Pliva, I then went back to Trazodone by Qualitestand, voila, meds working again!!!

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