Alprazolam Differences Bs (Top voted first)

I write blogs about drugs (mostly pills). I do not take any illegally obtained pills, but am prescribed two pain killers and two benzos. I have read about the "+ or - 20%" difference between brand and generic. Don't know about that. I'm going to check with an actual Dr. of Pharmacology instead of online references because 20% is HUGE. A 20% boost in Fentanyl or oxymorphone COULD lay you out. I'm thinking 2% is probably more to the truth. After all, the first time I heard this was an odd-duck doctor I had who would always write BRAND ONLY!! on his scripts. When I asked him, he said generic pills "weren't mixed properly, and that you could get one pill with ALL drug, no filler even, and another with all filler, or anything in between. That is not how drug production equipment works. You can look that up if you know the brand of dry ingredient mixer for sterile powder they use, which you can obtain usually by calling the company and asking to speak to engineering at their production facility. Weird? Not really. Sales people call on these departments all the time. Anyway, that false info came from a DOCTOR...so if the doc can misread or misunderstand, so can a patient. Having said all this: the "green bar-shaped Xanax" I've seen questions about are 2mg pills that (in Florida) are called "Green Bombs". They are preferred over all other 2mg Xanax, even the name brand ones. The $ is 1-3$ MORE, sometimes as much as 4$ more than standard white or pale yellow bars. Conversely, the 2mg Xanax that are NOT "bar-shaped" are 1-3$ LESS.

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There is a big difference between generics and brand. FDA allows more than 20% less efficacy. The compounds may be the same, but released at different rates. EVERY med of mine, including blood pressure med, has been doubled in dose, because they don't work.
Trust me. I am a nurse, and see the in effectiveness of the meds everyday.

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If you want to read about the 20% allowable difference for yourself to see the proof, you can Google the Hatch-Waxman Act of 1984, it's all in there.

However, wha you need to remember is that 20% isn't a huge difference, when you're talking about milligrams or fractions of milligrams.

Yes, that could mean that a 100mg pill actually contains anywhere from 80mgs to 120mgs, but if you're dealing with fractions, like some that only 0.25mcgs, then it's minuscule.

The FDA considers an acceptable therapeutic window.

Additionally, that doesn't mean that all generics differ by that much from their name brand counterparts. Some may differ by barely a fraction of a percent and some may not differ, at all.

Are there any questions or concerns?

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