Xtampza & Oxycodone Drug Interactions
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Can Oxycodone be given with Xtampza ER for break-thru pain?

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Yes u can I take 18 mg twice daily and I also take two 10 mg of oxycodone daily

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Re: Roy (# 1)

I take extended release oxycontin which is time-released which one of the active ingredients is oxycodone I also take oxycodone for immediate pain

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Yes, you can mix the 2 drugs! I'm taking Oxycontin and then Roxicodone for breakthrough pain aka Oxycodone. You're just adding instant release oxycodone to your extended released oxycodone. Millions of people do this everyday! Note: your version of extended-release oxycodone has the antagonist naloxone in it as an abuse-deterrent.

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Hi Red - Well, Xtampza is an extended release form of Oxycodone, so I think that technically what you are asking is if you can take both an immediate release and extended release Oxycodone in conjunction with one another? Unfortunately I'm not qualified to answer that without knowing your specific case, but I have read other comments on this site where someone is given one medication for breakthrough pain and another which is extended release. Your doctor or pharmacist should be able to provide some insight, or perhaps your doctor can even give you a proper prescription for a breakthrough pain medication. I hope this helps!

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