Which Is Stronger Hydrocodone 10 325 Or Oxycodone 5 325 (Top voted first)

I have been taking Hydrocodone 10/325 for chronic pain, 1 pill every 6 hours. My Dr. just prescribed Oxycodone 5/325 with up to 2 pills every 6 hours. Which is stronger?

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Scott is correct, the Oxycodone is actually stronger than the Hydrocodone.

To equal 10mgs of the Hydrocodone, you only need 6.67mgs of the Oxycodone, so I'd advise caution when you first take them, you probably shouldn't take 2 of them, until you try one and see how well it works for you.


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I had major back surgery back in 2006 and have been taking Hydrocodone 10/325 for 8 yrs and it stopped working for me all of a sudden, I read the label and they changed the manufactor of the hydrocodone to watson so I figured that was it but according to the pharmacy and Doctor it shouldnt have mattered but watson went from a yellow pill that worked for me to a white pill and I started hurting, the pharmacy told me they pulled the yellow pill off the shelf.So the Doctor prescrbed me oxycodone 5/325 and that pill makes me groggy and puts me in a bad mood and aggravated at the world unlike the yellow hydrocodone that I took so whats the advice from anyone about what should I take ????

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Which dosage has less aspirin? 2 oxy 5-325 OR 2 Hydro 10-325
Which dosage has more pain medicine ? 1 oxy 5-325 or 1 Hydro 10-325

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Your pharmacy is lying to you. They still have the yellow 10's you just have to find a pharmacy willing to order them. Mine does.

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Rae's post really ticks me off.I am a chronic pain patient, and NEVER HAD TO USE SOMEONE ELSE'S URINE! It's people like you that have made it harder for REAL patients to get the pain medications they need!

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That Sounds a right, But Just make sure that you dont get hooked.. I had Oxi 10's & 40's I like the 10's better. So just take it easy & God bless

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Can i take hydrocodone 10/325 during the day. Every 6 hours and one 15mg
of oxycodone at bedtime. I work and can not handle the oxycodone during the day. I have spinal stenosis. Terrible back and leg pain.

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Having managed a large psych clinic (also a former BOM and MSO manager for a psych hospital) I have some experience with prescription laws and prescribed medications.

First of all, FAROOQBALUCH1, doctors DO NOT receive a "commission" for prescribing ANY particular medications, whether brand name or their generic version of the same medicine. (This would be patently, without a doubt, illegal). It is true they might receive "special consideration or treatment" for prescribing brand name meds from some manufacturers, but always in the forms of catered lunches for the office staff and other similar types of percs, never in the form of cash or other forms of remuneration. (This happens most often when a brand-name medication is first released on the market.) Did you know that drug manufacturers know exactly which doctors in their assigned zone prescribes which medicines, and how many prescriptions and the strength of those medications? This has a lot to do with the fact that often doctors will stop prescribing old generic medicines (that often work much better and are usually much less expensive) in favor of new, brand-name medications.

Second, the color of generic (or any) medications has nothing to do with the efficacy, quality or strength of any particular pill. Colors are used only for identification purposes, to distinguish that pill from another pill.

Lastly, generic medications are neither stronger nor weaker than their brand-name counterparts. They absolutely must, by law, to contain the exact amount of the ingredients that are listed on the label. Any "perception" that one color is better or worse or stronger or weaker than another color is purely psychological.

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Tell your Dr to write ORIGINAL ONLY NON GENERIC on the script and you'll get the original Vicodin, Norco, Lortab instead of the often weaker generic counterpart. Good luck! Ben

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Work from home.

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Just a note: in preparations such as hydrocodone 10/325 bitartrate the 325 milligrams is acetaminophen-Tylenol. Not asprin. In any case each is not good for you in high doses for different reasons. On another note oxycodone is a little stronger than hydrocodone. The withdrawal from oxycodone is more uncomfortable than hydrocodone. This is because oxycodone works in slightly different ways.

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As a long time pain sufferer, and one who has been on Norco 7.5 for some time the change that occurred when the peach coloring was removed from the formulation also makes me wonder if the binding agents were changed? I too find a difference in pain relief. While the white will work, the pain relief lasts much less in terms of hours, 2-3 hours of relief instead of 5-6. It just seems as if the white is allowing the active medications to hit my system all at once and the peach was releasing slower, possibly because it was more difficult to digest? Again, I am not saying it is weaker, I am just suggesting that something else changed in the inactive ingredients/binders that has caused this change for many patients.

I have heard all the explanations, "they are the exact same thing, they have to be" from numerous sources but I and many many other patients with pain issues have to, respectfully, disagree. I have also heard the same complaints from people who are prescribed the 10mg Norco, when the coloring was removed.

Side note, I'm with Trish! You need to be straight with your doc. Even if you are self medicating in addition to your prescriptions your doc needs to be aware.

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No they can only test the kretin level in the kidneys. That just tells them if u urinate enough to be on a certain medicine.

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i am 57 and have been taking up to 5 hydro codone 10/325 a day for 3 years before that propoxyphene 65mgs in a cap for at about 13 years problems with back left knee right foot i am hooked will i be able stop this on my own i am in a lot of pain when there not in my system . if i hurt how can i find work

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The color has no effect on the medication. It's for distributing purposes only. They are differences in company's quality! I would recommend having the doctor put brand name only!

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I've had chronic pain for some years, migraines and problems with c5- c6 neck disk issues. Hydrocodon (aka: Norco) comes in 3 does 5mg/325; 7.5 mg/325 and 10mg 325.
Oycyodone (aka: Percocet/Endocet/Roxicodone) come in same strenghts.

Supposedly Oxycodone is a little stronger than Hydrocodone. My personal opinion is there are about the same. I do not agree with the charts, showing oxy a little more potent, it's identical as far as I can say. It comes down to which works better for you.

Please bear this in mind. If you have NOT taken much oxycodone before, a dose of 25 mg plus is FATAL.. No Joke. So you start with the lowest does 5 mg/325 acetamiphone (sorry spelling not my strong point) Over time you do build resistance to it. Over 15 years use I can handle 50 -60 mg at one time, bear in mind this will kill you if your not use to it. These drugs are SERIOUS business. Follow your doctors instructions to the letter one these.

The other choices are Morphine. Personally I don't like morphine, it gives me panic attacks after a few days, so no morphine for me. There are two new opiates. Opana is supposedly a strong pain controller with few side effects. Personally more panics attacks for me. There is a second new one Nycenta, I havent tried this one because pharmacist told me if Opana gives me panic attacks Nycenta probably will to.

Your other choices are diulaudid (hydromorphine) I tired it works so-so. There is methadone and it is a good pain drug, but it has the social stigma associated with it, its for drug addicts. If you have dental issues methadone isnt for you.

Since last Ocotber DEA has changed its regulations on all these C-2 narcotics. The pharmacies are having a hard time getting them. What the hell is this about? I have been compl,aining to my US Senator and Congressman about this. Sure we have drug problem in usa, but you dont deal with the probelm by trying to cut supply because people with chronic pain, really do need these.

But these are serious drugs which can kill, like I just said you you have to follow the docotors instructions. Like any generics different brands works good for some and are junk for others. Watson Hydrocodone is pretty good. There oxycodone isn;t so great. Mallickroot is so-so hydro and oxys. Personally I like endo brand, for me it works best, Here you have to try the different brand to see which works best for you bottom line.

The plain oxycodone/roxidone brands are best, but not easy to get since Oct and the fed reg changes. Complain to your congressman about it. You don't get the acetamiphone combo with the narcotic. People with liver issues should not take acetamiphone combos, but the narcotic with acet does work a little better pain control wise.

Bottom line is try different brands and see what works for you. Follow your doctors instructions about doseae unless your sucidial.

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If you want to know if your dr receives anything from a Pharmacutical Company, put Dollars For Doctors in your search bar. This info is public and free to find out.

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Think of it this way 5mg of oxycodone is equal to 6.67 of a 10/325 of the norco so if your taking 2 every 6 yrs is like taking 13.5 of norco also take into consideration that like other posts have stated that the fda gives a leway of up to 20% so norco can be 8/325 or 12/325 but that requires more pain medication do you think they will lean towards the higher does (no) if you can ask your doctor to give you brand name and depending on your insurance they may cover it pharmacist will tell you it doesn't make a difference but I have a cousin that formulate medication and by the company and the fda they choose the lesser he makes medication in Mexico so when I go to visit him I call him in advance and he makes 10 mg and believe me they really last almost 6hrs and when I get back to San Diego and get my script they maybe last 3 yrs. So yes the oxycodone is stronger hope this helps and you get better.

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Neither of these meds contain aspirin. They do, however contain tylenol or acetaminophen. Aspirin and acetaminophen are totally different medications. They do work the same in certain conditions but the risks of taking aspirin are vastly different than those of acetaminophen. The abbreviation for aspirin is ASA. The abbreviation for tylenol is acetaminophen. Aspirin should never be taken when Tylenol is prescribed. I cannot emphasize enough how these two medications are very different medications.
For many years the two medications have been used interchangeably but we need to make ourselves aware of the differences. If you don't understand the differences please discuss the matter with your doctor or pharmacist. As far as I know, aspirin is never used long term where Tylenol can be. With that being said, please know that Tylenol in large doses can be very harmful.

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The same thing happened to me. The yellow very effective; but not the white narco; they still make the yellow but my pharmacy said they contract with the other company now so will only give me the white; I suspect cheaper for them. I told the company the yellow is more effective and they said they will tell management and if enough people say that they will go back to getting the yellow, but that most people don't complain. So if we keep voicing our opinion to Albertsons and Safeway they will change their policy.

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