What's The Difference Between Norco Mfg Tris Vs. Mfg Actavis?

I have been on Norco 10-325 for chronic pain and normally have no issues. My last prescription appeared to be more oblong and was manufactured by MFG TRIS and I’ve noticed that I’m nauseous quite often. Why do these make me sick but the ones by MFG ACTAVIS don’t?

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Hi Kaylee,

Sorry to hear about your situation. To my understanding, the only difference should be the list of inactive ingredients (binders/fillers) that help make up the composition of the pill. In some cases, an individual may be allergic or hypersensitive to certain fillers which can be an underlying cause of side effects.

Something fishy about Tris Pharma compared to other manufacturers is that they don't share their list of inactive ingredients so we have no way of knowing what fillers or how many fillers are truly in these tablets.

Norco by Tris Pharma
Description: A capsule-shaped white tablet imprinted with G037
NDC: 27808-037
Size (mm): 16

[1] trispharma.com/generics
[2] dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d4caec6d
[3] dailymed.nlm.nih.gov/dailymed/medguide.cfm?setid=d4caec6d

Three different reputable sources and no mention of what fillers are used is a red flag to me... However, you can try contacting Tris Pharma directly via their Customer Concerns and Product Issues hotline at:

Phone: (732) 940-0358
Fax: (732) 940-0374
[email protected]

On the other hand, Norco 10/325 by Actavis (Watson) seems to be more transparent...
Description: A capsule-shaped white tablet imprinted with NORCO;539
NDC: 52544-161
Size (mm): 14

Inactive Ingredients:
-Croscarmellose Sodium
-Crospovidone
-Magnesium Stearate
-Cellulose, Microcrystalline
-Povidones
-Starch, Corn
-Stearic Acid

Please post back if you find out any more details!

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Re: David (# 1)

I have since changed to a different pharmacy that does not use Tris and have not had any problems. It is definitely whatever the manufacture uses that made me sick.

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