Watson Vs Mallinckrodt Norco

I have been prescribed Watson brand Norco for years. Recently I was given this same drug made by a different manufacturer (Mallinckrodt). This formulation gave me headaches, cramps, hives and I'm vomiting. Why?

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Hi Lee,

Whenever you switch manufacturers of the same drug, there's almost always going to be a difference in inert ingredients (binders & fillers) that make up the composition of the pill. Some people are more sensitive (or allergic) than others to these changes and that in itself may be a culprit for possible side effects.

Something else worth noting is that different binding agents can affect bioavailability, which in turn means you get more or less of the actual active ingredient, potentially bringing about an onset of withdrawal symptoms.

Unfortunately, determining which one of these underlying factors is the true culprit may be a guessing game. I think it just comes down to working closely with your doctor/pharmacist through trial and error in order to find out which manufacturer's version of Norco serves you best.

Hope this helps!

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