There Is A Difference Between Generic Brands Of Norco!

I've been taking Norco 10/325 for quite some time and have noticed a MAJOR difference in quality and effectiveness between manufacturers. To me the Mallinckrodt 367 are the most effective all around. Interpharm/Amneal (same company /have merged) IP110 version comes in second for me. Watson seems to be the worst with noticeably much less effectivepain relief and with me seems to act more like a sedative, knocking me out which sucks when you want to be functional/productive. Qualitest is okay but seems to be similar to the Watsons only with less sedation. Personally if the pharmacy doesn't carry Mallinckrodt or Interpharm/Amneal then I won't fill my prescription there. I know this subject has been discussed here many times before but I figure since the recent apparent formula changes in the once preferred brands it'd be good to share with each other our recent experiences

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Thanks for the heads up Johnny. While I agree that there are differences between generic brands of norco, my personal stance on all the different brands/generics hasn't changed much, namely because I realize that no matter which manufacturer's brand/generic works great for one person, it could still very well have a different effect on someone else.

The game of trial and error still has to be played by each individual since their body may respond differently to the various types of binders and fillers that are inconsistent from one tablet to the next.

My understanding is that even though the dosage may be the same, the "so-called" inactive ingredients are what have always been scrutinized for affecting bioavailability / overall efficacy either for better or for worse.

So upon comparing different brands/generics, I think it would be just as important to take these ingredients into consideration in order to know which substances are causing one tablet to provide more relief than another at the same dosage.

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