Subutex Question For Someone That Really Really Really Knows! (Page 3) (Top voted first)
UpdatedLooooong read. I warn you now :)
Ok. PLEASE don't explain how it works or what it does. Save yourself the time. I am extremely familiar with how it works and what it does.
But I have a question that's been on my mind for many moons, forever actually (10 plus years) and I can't seem to get a straight answer to it no matter how many times I ask it and where I ask it. I am asking it here for the first time.
Just always get the usual, familiar rhetoric explaining to me how it works and where it binds and what it does, blah blah blah, but no one ever can explain the "why" behind all this wonderful science!
And at the end have one first hand case PROVING what I'm questioning to be true.
Ok so follow. So if buprenorphine is stronger than and has a higher affinity than let's say Oxycodone as a real life example, and will kick off that opioid from the receptor, this meaning it "replaces" it and fills it, then WHY bother waiting to take it?
Immediately or 24 hours later, either way, it's going to sit in that same receptor and do the exact same job!!!
I'm so tired of reading about this precipitated withdrawal crap. Now, tired of reading about it does NOT equate to not believing it. You would be an ***** not to believe it because there are just too many cases of it to be ignored so it's a real thing. I just don't understand WHY it's a real thing?
Because I cannot POSSIBLY imagine why having the opiate kicked off the receptor immediately, or having the remains of it kicked off 24 hours later, can produce such drastic night and day results?
Heck, I've know addicts that were given Narcan to reverse overdoses who didn't go through such pain as you read about some people trying to come off with Subutex or suboxone too soon and not waiting long enough!
24 stinking hours? Seriously? I mean I just don't understand WHY it would be ANY more painful OR horrible OR agonizing to just take the Subutex at anytime you want whether it's during opiate intake, an hour after Intake, or 24 hours after opiate intake, either way, no matter WHEN it is done, it is going to perform the exact same function. It's going to kick it off and replace anything that's in its way!
So why if you took it too soon would you go into agonizing withdrawal? You should NOT be going into ANY withdrawal whatsoever even if you take it immediately, because it immediately fills the receptor and prevents withdrawal.
I mean that's the entire purpose of this drug is to prevent withdrawal. That's what it is designed to do. That's what it's made to do. Whether you take it immediately or 24-36 hours later?
I mean if it took a couple weeks after you stopped taking opioids to go into withdrawal and then you could use Subutex maybe I could understand why it would matter if you did it immediately but 24 hours? That's absurd to my brain!
Now for the proof I was speaking of. After enduring watching my wife going on and off Suboxone a dozen plus times, each and every time having to watch her in agony as she detoxed off Percocets for 24 hours first. (Heavily researched this drug before I tried to put her on it for the first time and had that SAME question THEN 10 years ago)
Sitting back and watching her do something that I had ALWAYS considered to be useless, what I ALWAYS considered to be needless and what I ALWAYS considered to be nothing more than a ploy the doctors PURPOSEFULLY do as well as the manufacturer, that is to put the patient into DEEP detox so they can become their NEW PIMP, and heroes and rescuers, I ran across a small psychiatrist in Texas..
Giving up on explaining my theory to him as I had already convinced myself there was no need to detox first, was only being done to hook the patients on a very expensive product, the psychiatrist started laughing when I asked him about the usual 24 hour detox.
He became my white knight in shining armor when he said "no that's ridiculous, Suboxone will immediately replace the opiates and there's no advantage one way or the other to doing a detox first"
Smiling from ear to ear but refraining from telling him I have always thought that, for the first time after dozens of times I gave it to my wife WITHOUT waiting and guess what?
Yep that's right, she immediately responded, felt great, and took up right where she left off after just doing a couple Percocets a couple hours before, thus proving that she NEVER needed to do that 24 hours first as I have always thought.
But my question remains, I have seen far too many documented stories of precipitated withdrawal as well as read tons of agonizing stories that were NOT precipitated but just more or less people who went through living hell by doing it too soon... when there's absolutely no medical or scientific reason why they should have???
What gives???
Re: Winston Dr (# 30)
Stand corrected didn’t see prior post as you made two! Wrote long reply but under review and may take few days to show.
Re: Winston Dr (# 30)
You have no idea what you're talking about. You'll get the same effect from either, -utex or 'xone. The Naloxone is in it ONLY TO PREVENT INTRAVENOUS USE. Further more, telling people it's so people don't abuse bups is also wrong. Bupes have a 32mg ceiling effect, taking more does nothing. As far as PW is concerned...I waited 36 hours. Way too many of my junkie acquaintances claim PW, I wasn't going to chance it. I was on methadone 27 years. Not a few silly percs...
That’s a bunch of bs! I’ve never ever heard of anybody have withdraws from dissing too soon.
ANS AS FAR AS BEING STUPID YOUR THE BIG DUMMY THAT JUMPED FROM THE FRYING PAN AND INTO THE FIRE! “ or your wife- both?) I had a lil ol percet problem you could kick in a week and ( u or she ) started takeing subs? NOW THATS SO STUPID!!!! U JUST “THINK” u had withdraws! GO 3-4 DAYS WITHOUT YOUR SUBS!!! AND TELL ME HOW THATS WORKIN FOR U!!!! Hahaha! U could’ve kicked a Lil ol stupid pain pill crap in a week! Now you’re a lifer on subs! Unless u can go sick as crap for about a month!
Now.... WHOS THE STUPID ASS? Yeah,
Re: Kim (# 44)
If that someone is YOU, with the memory and intellect of a dead animal, I think it’s very possible. But for most individuals with a decent amount of intellect it won’t be hard to follow... as made note by the dozens and dozens and dozens of replies, except yours, which means u don’t understand the question because it’s over your head, so you attack it! LOL
Re: Kim (# 43)
People just “think” they have withdrawals??? MY GOD WOMAN. You really are stupendously stupid. Why are you here posting with such an ignorant understanding of opiates?
Re: RustedOne (# 47)
Says the guy who disagrees with a DOCTOR that specializes in this area! Let’s see, who shall I believe...
Re: Kim (# 51)
LMAO!!! Read like the first sentence and stopped. It’s all useless babble. You are seriously a disturbed individual. You DO know that right??? You need help. And you probably won’t find it here. Bye :)
Re: Master Plumber (# 46)
PLEASE! I’ve been on sub for probably longer than you've been alive! I understand it just fine. What I can’t understand is, WHAT BUSINESS IS IT OF YOURS? Or you're so freaking bored u find time to call names online?
Re: Master Plumber (# 52)
I didn’t come for help! U did! And it doesn’t look like anyone’s going to answer a question that’s somewhere in a 1000000000 word question!
Re: Master Plumber (# 50)
I wasn’t making trouble! I was being as polite as I could be!! TILL I WAS CALLED NAMES! IT IS ME THAT'S STARTING TROUBLE!!!! It takes a big man to mistreat a 140 lb women online!
Re: Master Plumber (# 45)
And men that attack a women or nothing but animals! And if u were within driving distance my husband would show you what a dead animal is u ah! Big Man U r u r
RustedOne (# 54) --
Are you still here? Must have a pretty worthless life to get your excitement off of a thread!!!!!!
Re: Kim (# 53)
Blah blah blah blah... You and your newfound cohort that up until this point was an excellent thread and had dozens of fine replies was great till you and Mr. ***** came along making fun of me and the doctors who replied and attacking the thread is a sure fire example of how you are mentally unstable as well as your other friend Rusty (rusted in the head). Just the fact that you’re wasting your time on such a thread is nothing more than a clear example of how useless your life must be. Going to have your husband kick my butt??? My God go away!!! LMAO
Re: Master Plumber (# 46)
Idk!youre such a smart ass you know all of everything! You ask and answer your own questions . If you’re a real plumber I wish you’d plug up that big as hole in your head that u use to talk with!
I hope u get your fat a;:- stuck under a house! I And have to crawl in raw sewer! U turd! While your in detox would be FANTASTIC! ! I doubt nobody would look for you!
Re: Kim (# 60)
I changed my mind. You’re not stupid and mentally unstable. You’re evidently 12-years-old after that last post!
How’s everyone doing!? Subutex is only a partial opioid. There are 3 different receptors that I know of. Buponorphine only has an affinity for one as full opiates bind to all the receptors. Taking subutex is stronger when binding to the specific receptor kicking in off the weaker oxy ect... throwing the body into a chemical imbalance hence precipitated withdrawals can incur
Re: Matty b (# 62)
Thank God, we are back to normal replies before those last half-dozen or so!!!
Hello Marty :) I guess my question would be that let’s assume all of that is correct and it sounds correct to me. The question still remains as regardless of what transpires when you take it, the exact same thing is going to take place 24 hours later as well. The question I am trying to ask is what is the difference between now are 24 hours from now? That’s what it all comes down to.
So what you’re really saying is that the sub is only going to knock the oxy off one receptor which means the other two receptors will stay full which is all the MORE reason to believe that there’s no need to wait 24 hours.
In theory waiting 24 hours will actually be worse because then you’re going to have two extra receptors that are empty and only one when you take it where as doing it immediately all three are full. So again something is still not right :)
In my experience it seemed methadone was the med that would send u into withdrawals if mixed within 72hrs. I lied to the Dr. about my time frame and I paid dearly for it! It had only been about 26hrs! The Dr. could have “slipped me a micky” knowing I’d get sick. And like u say, the next day he comes they like a hero with the super drug! But it’s always methadomes to Suboxe not Suboxe to methadones. Being on domes first so it’s actually in ur system for some time.
If you get the white pop out under the tongue that you slide out with, read the how, what, when and why... It will answer all your questions.
I don’t remember waiting to take suboxone when I switched over.
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