Subutex 460 Vs 54 411 (Top voted first)

Does the Buprenorphine 8mg 460 work as well as 54 411's? I'm curious as I've seen other imprints, just not 460. Please let me know if they are better or worse.

REPLY

REPORT

I just got my prescription today seems like the whole of the North east will be switching because CVS is now giving out the 460 ones since they got a better deal or something. I do not like the 460 as they feel like they are burning my mouth when they dissolve. how do others feel thanks.

REPLY

Was this helpful? 40

Among other influential factors, some people may respond better or worse to the different binders/fillers upon switching from one tablet to the next. That said, the only true way to compare efficacy is to go through trial and error with both versions yourself and not solely based off someone else's feedback.

Inactive ingredients in the 460 pill are:
Lactose Monohydrate, Mannitol, Povidones, Anhydrous Citric Acid, Sodium Citrate, Butylated Hydroxyanisole, Magnesium Stearate, Corn Starch

Inactive ingredients in the 54 411 pill are:
Anhydrous Citric Acid, Corn Starch, Crospovidone, Lactose Monohydrate, Magnesium Stearate, Mannitol, Povidone, Sodium Citrate

NOTE: Even though 'most' of what's listed is similar, the order in which they are listed is different, which from my understanding means they are probably present in varying quantities relative to one another. We may never know if a patient is more or less sensitive to a specific inert substance, but hopefully this will help others on here determine why their system might prefer one over the other...

National Drug Codes for reference of inactive ingredients: 62756-460 / 00054-0177

REPLY

Was this helpful? 21

No, the 460's do not help me or anyone I know. They have a funky taste and make my stomach upset.

REPLY

Was this helpful? 22

I followed the exact actions / instructions above in the thread and called cvs customer relations to complain about the new sun pharma 460 8mg subutex tablets. All I want is my regular Roxane version I have been successfully on for almost a year with no issues. The sun brand has caused a burning sensation under my tongue leaving red irritated burn areas and ulcers. It has also caused constipation, upset stomach, lack of appetite, and issues I never had on the Roxane brand. And I also find it wears off much sooner, where my normal dose could get me through a 12 hour work day just fine. I found myself having cravings partway through the day feeling the need to take larger doses or more frequent smaller doses to make it through the day. They have had my stomach in ruins. This is no placebo affect, I have been on them for 2 months and the pharmacist said I would adjust in "7 days" to the new brand. They are hazardous and harming the health of my mouth dramatically and causing cravings for the first time in 10 months. I called customer helpline at cvs, and they did take my concerns very seriously. And are currently elevating it to the district customer manager. They said all cvs will be switching to this new brand (at least on the east coast). Everyone should being calling cvs' customer helpline. If we don't band together and do something about it we will be stuck with the cheaper (more profits per pill for cvs each time they switch) and inferior brand that does not do what it's intended purpose is, and causes harmful side effects.

If enough people call, based on the conversation I had with cvs corporate customer service helpline, and complain of the mouth acidicness, sores, and stomach issues I do believe cvs would have no choice but to switch back to the good o'll 54-411 Roxane west labs brand they carried for years. Or a substitute of equal quality. I personally believe these are harmful and should be taken off the shelves. And after 2 months on them I can guarantee you the potency is not the same (or absorption is not) if I did not have some extra 54-411's around from previous scripts I wouldn't have been able to make it through either month without running out of my meds just to get the normal day to day feeling I had from my original brand. Have also noticed a severe lack of energy due to this new brand. So I encourage anyone who uses cvs to call the customer helpline (1-800-746-7287) and complain about this brand. So we can get a safer, better brand that works, or the best brand back they sold for years. We have to form a community on these things. Cvs said they had no idea this new medicine had any side effects the Roxane brand didn't. If no one calls to let them know they won't know to do anything about it. Until then I am boycotting cvs (normally my favorite and go to pharm) until I can get a medication that works for me without the bad side effects and less potency. Hope this info helps someone else caught in my situation. The district manager is supposed to call me tomorrow, and hopefully figure out a store they can order my normal brand from. A polite conversation on the phone can make them aware it's inferior (and unsafe in my opinion for oral health) and make them take action.

REPLY

Was this helpful? 17

UPDATE: Sun Pharmaceuticals manufactures buprenorphine as a white pill with a 460 imprint on one side. CVS normally dispenses buprenorphine manufactured by Mylan (a white pill with 54 411 imprint on one side). I called CVS Customer Relations regarding Sun Pharmaceuticals product. I reported terrible burning sensation as the pill dissolves and subsequent upset stomach. They explained that Mylan itself was out of stock. However CVS escalated my complaint to the District Pharmaceuticals Supervisor. She was extremely accommodating. She did a search of other CVS stores in my area and found one that still had the Mylan product. She arranged for a driver to deliver the appropriate number of pills to my residence and exchange them for the Sun Pharmaceuticals 460s. I'm very grateful to CVS for their amazing customer service.

REPLY

Was this helpful? 15

I feel like they burn my mouth as well and I've been freaking out and I called my pharmacist and they basically thought I was crazy for saying it burned my mouth.

REPLY

Was this helpful? 9

Shawn spice, you most definitely need to do some looking online cuz you don't know anything!!! Any NORMAL person would know suboxone is buprenorphine and naloxone (naloxone is a blocker so you "can't" use other drugs with it, it will do nothing). SUBUTEX is straight buprenorphine with no blocker. Which is commonly prescribed to pregnant women or breastfeeding moms.. some have an allergic reaction to suboxone and have to be prescribed subutex. Anyways before you come In here looking like mr. know-it-all, you might want to make sure your "facts" are even true... now you just look like a ****** who doesn't know anything about the medication... Have a great day!

REPLY

Was this helpful? 8

I'm so glad I'm not the only one. I've been on the 460s for a week now as opposed to my 54411 and I feel awful! Terrible cravings! I haven't felt this way the entire time I've been on subs. It's causing me to have panic attacks because I want to use. I hate it so much I don't know what to do!

REPLY

Was this helpful? 10

Please don't get the 460 buprenorphine. They're are making thousands sick and I highly advise you don't go to CVS because they're the ones carrying them. I advise anyone who has had this brand prescribed to call the CVS Helpline and report any adverse side effects.

REPLY

Was this helpful? 6

Try going to rite aid or walgreens walgreens has little tiny ones with an 8 imprinted on them rite aid did too but rite aid was kind enough to order me my normal 54 411 so glad cvs was out of them in my town. I have been on buprenorphine for a little over 11 years now i am on it for pain management

REPLY

Was this helpful? 5

Regarding CVS's switch to Sun Labs 460 buprenorphine: I got a very quick and genuinely concerned response as a result of calling the Pharmaceuticals Supervisor for the Northeast Region. Her name is {edited for privacy} and I believe she works out of Providence. Prior to speaking with her, I had called CVS Customer Relations at 844-239-6923. The folks there ultimately hooked me up with the Supervisor. It might be best to start by calling Customer Relations since their's is a publicly available number.

REPLY

Was this helpful? 6

It's Westward brand that makes the 54 411 bup. I think we all need to call CVS and complain before we all RELAPSE

REPLY

Was this helpful? 6

Your very welcome. I encourage also that we STOP BUYING THE WORTHLESS 460 SUBS FROM CVS. Maybe, just maybe, if we collectively stop buying them Wentworth/Sun. will begin to notice. Stocks will drop. "We need a sub revolution..'Its very serious I know. I've tried all the subs being on them this long. Now they are equivalent to Actavis; wear off / weak. Hi Tech being the worst. It's at the point I'm ready to say f it and get on the suboxone strips. I posted all their info. I filed complaints against them. CVS has no control, they give us what their warehouse sends. So I am so weary from all this. I'm sick. I'm so concerned about all the rest of us out there suffering. God forbid relapsing. Anyway God bless us all.

REPLY

Was this helpful? 5

WOULD ANYONE BE INTERESTED IN STARTING A PETITION TO PROVE THAT THESE BIG CHAIN PHARMACIES (CVS, WALMART, RITE AID, WALGREENS ETC) TREAT US UNFAIRLY BECAUSE OF THE PRESCRIPTION WE GET, REFUSE TO ORDER OUR PREFERRED MEDICATION WHEN THEY VERY WELL COULD EASILY DO SO, AND REFUSE TO FILL OUR PRESCRIPTIONS FOR REASONS LIKE THEY'RE NOT ACCEPTING NEW PATIENTS (BUT ONLY FOR THAT MEDICATION), OR BECAUSE OF WHERE WE LIVE OR WHERE OUR DOCTOR'S OFFICE IS, OR ONLY IF WE PAY WITH CASH -- IT'S NOT RIGHT! IT'S DISCRIMINATION! AND ONLY OUR SPEAKING UP WILL CHANGE THAT BECAUSE THE ONLY THING THEY CARE ABOUT IS PROTECTING THEIR REPUTATION! REPLY WITH MY NAME IN THE COMMENT TO LET ME KNOW WHAT YOU THINK! THANKS!.

REPLY

Was this helpful? 5

Re: shawn spice (# 60)
you're completely wrong. Subutex and suboxone are 2 different medications. They both have bupernorphine but suboxone has nalaxone and subutex does not. Don't speak on things you don't know about. It makes you look uneducated and stupid.

REPLY

Was this helpful? 5

If you are in New England as I am maybe try going to walgreens or rite aid walgreens has little ones with an 8 imprinted on one side they seem to work just as well. When I went to fill my subutex this month cvs was out of them thank God and I went to rite aid they only had a few but they said that they would order them for me they had the little ones too which can make me nauseous so I asked if they could order my regular 54 411 for Me they were very helpful and accommodating. So maybe you can try this next time. I have been on then for over a decade for pain management and these work great I hate when pharmacies do this crap all to make more money. Well best of luck

REPLY

Was this helpful? 5

These burn under my toungue as well. I thought something was wrong with me because the 54 411 never did that. It seems there's no way to resolve it either. I live on the KY/OH border and KY pharmacies will not fill for my Ohio Dr due to laws pertaining to KY that do not apply in Ohio. I am a pain management patient for several years now with no troubles til now. There is a rite aid in KY but not one around here in Ohio.

REPLY

Was this helpful? 5

I just took the 460 version of buprenorphine for the first time. It has a terrible taste and elicits a really unpleasant burning sensation as it's dissolving. Worst of all is the awful upset stomach to which others refer. I was planning to have dinner shortly. Guess I'll just wait a while.

REPLY

Was this helpful? 6

My mistake... Mylan's buprenorphine carries an imprint of M 924. CVS has previously carried Mylan, as well as Roxanne which has an imprint of 54 411. Both are acceptable generics.

REPLY

Was this helpful? 4

Yes seems cvs is fazing out the Westward/Roxanne brand for this Sun Pharma 460. Had the 460's this past month. Awful taste, burns mouth, more headaches & felt bupe less then Roxanne brand which I've taken for 6+ years. The pharmacist said they would "try" to order for me. Looks like I may be shopping mom & pop pharms if cvs won't budge. They're going to lose lots of customers that are sub takers.

REPLY

Was this helpful? 5

I'm trying to stop using H and I have the 54 411, round, white, subutex pills. Do I have to wait 24 hours from my la...

4 REPLIES

I have run out of options with "pain pills" have been inquiring about subutex as a pain reliever for chronic pai...

2 REPLIES

A friend of mine told me her pharmacy told her they were going to be only getting the small round generic subutex tablet...

5 REPLIES

I cannot take the teva brand subutex it stops my period for 5 to 7 months I cannot take suboxone with naloxone it stops ...

5 REPLIES

I have an 8mg subutex.ive been on suboxone for ten months and now im out of meds. Will this subutex replace the suboxone...

1 REPLY

Has anyone ever taken or hear about a peach/orange covered, oval subutex with the inscription 54 411 on it? .. I can'...

3 REPLIES

I get 60 of the 54 411 subutex a month. Need to save. What is the best discount card to use and what pharmacy do I use i...

2 REPLIES

How soon can I take subutex after taking hydrocodone? ## Hello, Becky! How are you? You have to be in full withdrawal, b...

12 REPLIES

Does meijer pharmacy carry 54-411 subutex or M 9-24? Walmart was out of 54-411 and I cant take the M 9-24 version. The p...

16 REPLIES

I found Subutex in my daughter's room with a needle. Do people really IV this? Why do people take it that dont need ...

347 REPLIES