Started Keppra And Experiencing Severe Pain On Skin Of Feet

My son, 37, had a massive stroke caused by sepsis 19 months ago. He had neuropathy in both feet, got a strp infection in his feet which went septic and then had the stroke. He then had charcot foot bilaterally, very severely, which has been corrected as much as possible over last year thru surgery. He suffered a seizure 10 months ago from being put on Ultram. Now 3 days ago, he suffered another seizure blamed just on having a lowered seizure threshhold. He was put on 500mg Keppra every 12 hours. This morning, he started having extremely severe pain in his feet on the skin and the pain is moving around on the bottoms and tops of his feet. He has endured extreme amounts of pain in the past, but this is SO sharp and burning that he cries out every time it hits him... which is every few moments. Should he be changed to a different anti-seizure med? We called his doctor, and the attending for the day would not change it, although I spoke to a friend who is a physician in another state and she was sure the meds would and should be changed. My son is afraid to have another seizure, but also cannot endure this pain.

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Hello, Anci! How is your son doing? I am so very sorry about what he's been going through.

Yes, as reported by the U.S. FDA, this medication is actually commonly known to cause pain in various areas of the body. It can also cause mood swings, headaches, personality changes and weight gain.

You need to speak to his regular doctor about this problem.

When my husband tried this medication, he experienced a severe personality change and had to be taken off it. He's doing well with the next one they tried, which is Oxcarbazepine. So you may want to ask his doctor about trying it.

Is there anything else I can help with?

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