Smz Tmp Contraindications

What is the contraindication for SMZ-TMP?

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Sulfamethoxazole and Trimethoprim is contraindicated in patients with a known hypersensitivity to trimethoprim or sulfonamides and in patients with documented megaloblastic anemia due to folate deficiency.

Sulfamethoxazole and Trimethoprim is also contraindicated in pregnant patients and nursing mothers, because sulfonamides pass the placenta and are excreted in the milk and may cause kernicterus.

Sulfamethoxazole and Trimethoprim is contraindicated in pediatric patients less than 2 months of age.

Sulfamethoxazole and Trimethoprim is also contraindicated in patients with marked hepatic damage or with severe renal insufficiency when renal function status cannot be monitored.

Sulfamethoxazole and Trimethoprim should be given with caution to patients with impaired renal or hepatic function, to those with possible folate deficiency (e.g., the elderly, chronic alcoholics, patients receiving anticonvulsant therapy, patients with malabsorption syndrome, and patients in malnutrition states) and to those with severe allergies or bronchial asthma.

Furthermore, you can view a detailed description of the drug by clicking on the link below...
https:/­/­rxchat.com/­wiki/­Sulfamethoxazole+%2B+Trimethoprim%2C+SMX%2DTMP/­

The patient's doctor will prescribe this medication based on the condition, contradictions/precautions listed above, the patient's medical history, current health, age, weight, and other determinants used for verification. As with any medication it is best to have your doctor explain any precautionary rules before taking it.

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